The Alopecia Areata Consensus of Experts (ACE) study: Results of an international expert opinion on treatments for alopecia areata.
💡 한 문장 핵심
원형탈모증 전문가 합의(ACE) 연구: 원형탈모증 치료에 관한 국제 전문가 의견 결과.
메타분석
5/5 보강
TL;DR
Despite divergent opinions amongst experts, consensus was achieved on a number of pertinent questions and the concluding statement highlights areas where expert consensus is lacking and where an international patient registry could enable further research.
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연도별 인용 (2012–2026) · 합계 197
OpenAlex 토픽 ·
Hair Growth and Disorders
Acne and Rosacea Treatments and Effects
Facial Rejuvenation and Surgery Techniques
🇰🇷 한글 요약 🌐 Abstract
【연구 목적】
원형 탈모증(alopecia areata, AA) 치료에 대한 고품질 무작위 대조 연구 근거가 부족한 상황에서, 다양한 치료법의 사용과 유용성에 관한 국제 전문가 합의문을 도출하고자 함.
【방법】
5개 대륙의 모발 전문가 50명을 대상으로 3라운드 델파이(Delphi) 기법을 시행하였으며, 66% 이상의 동의율을 합의로 정의함. 3라운드에서는 대면 회의를 진행함.
【주요 결과】
총 423개 질문 중 1라운드에서는 5%(22개)만 합의에 도달하였고, 최종적으로 33%(130개) 치료 관련 질문에서 합의가 이루어짐. 병변내 주사(intralesional) 치료가 68%로 가장 높은 합의율을 보였고, 국소(topical) 치료 43%, 전신(systemic) 치료 36% 순이었으며, 광선치료(phototherapy)와 비처방 치료는 합의율이 가장 낮았음.
【임상적 시사점 (성형외과 의사 관점)】
모발이식 또는 두피 시술 전후 원형 탈모증 환자 관리 시, 병변내 스테로이드 주사(intralesional corticosteroid injection)가 전문가 합의도가 가장 높은 1차 치료 옵션으로 활용 가능함. 다만 전신 치료와 광선치료는 전문가 간 의견 차가 크므로 단독 결정보다는 피부과 협진을 통해 결정하는 것이 안전하며, 시술 전 활동성 AA 환자에서는 안정화 후 시술을 고려해야 함.
[BACKGROUND] A systematic review failed to identify any systemic therapy used in alopecia areata (AA) where use is supported by robust evidence from high-quality randomized controlled trials.
[OBJECTIVE] To produce an international consensus statement on the use and utility of various treatments for AA.
[METHODS] Fifty hair experts from 5 continents were invited to participate in a 3-round Delphi process. Agreement of 66% or greater was considered consensus.
[RESULTS] In the first round, consensus was achieved in 22 of 423 (5%) questions. After a face-to-face meeting in round 3, overall, consensus was achieved for only 130 (33%) treatment-specific questions. There was greater consensus for intralesional treatment of AA (19 [68%]) followed by topical treatment (25 [43%]). Consensus was achieved in 45 (36%) questions pertaining to systemic therapies in AA. The categories with the least consensus were phototherapy and nonprescription therapies.
[LIMITATIONS] The study included a comprehensive list of systemic treatments for AA but not all treatments used.
[CONCLUSION] Despite divergent opinions among experts, consensus was achieved on a number of pertinent questions. The concluding statement also highlights areas where expert consensus is lacking and where an international patient registry could enable further research.
[OBJECTIVE] To produce an international consensus statement on the use and utility of various treatments for AA.
[METHODS] Fifty hair experts from 5 continents were invited to participate in a 3-round Delphi process. Agreement of 66% or greater was considered consensus.
[RESULTS] In the first round, consensus was achieved in 22 of 423 (5%) questions. After a face-to-face meeting in round 3, overall, consensus was achieved for only 130 (33%) treatment-specific questions. There was greater consensus for intralesional treatment of AA (19 [68%]) followed by topical treatment (25 [43%]). Consensus was achieved in 45 (36%) questions pertaining to systemic therapies in AA. The categories with the least consensus were phototherapy and nonprescription therapies.
[LIMITATIONS] The study included a comprehensive list of systemic treatments for AA but not all treatments used.
[CONCLUSION] Despite divergent opinions among experts, consensus was achieved on a number of pertinent questions. The concluding statement also highlights areas where expert consensus is lacking and where an international patient registry could enable further research.
- 연구 설계 systematic review
【연구 목적】 원형 탈모증(alopecia areata, AA) 치료에 대한 고품질 무작위 대조 연구 근거가 부족한 상황에서, 다양한 치료법의 사용과 유용성에 관한 국제 전문가 합의문을 도출하고자 함.
APA 7
Meah, N., Wall, D., York, K., Bhoyrul, B., Bokhari, L., Sigall, D. A., Bergfeld, W. F., Betz, R. C., Blume-Peytavi, U., Callender, V., Chitreddy, V., Combalia, A., Cotsarelis, G., Craiglow, B., Donovan, J., Eisman, S., Farrant, P., Green, J., Grimalt, R., Harries, M., & ... (2020). The alopecia areata consensus of experts (ace) study: Results of an international expert opinion on treatments for alopecia areata.. Journal of the American Academy of Dermatology, 83(1), 123-130. https://doi.org/10.1016/j.jaad.2020.03.004
Vancouver
Meah N, Wall D, York K, Bhoyrul B, Bokhari L, Sigall DA, et al. The Alopecia Areata Consensus of Experts (ACE) study: Results of an international expert opinion on treatments for alopecia areata. Jour. Amer. Acad. Derm.. 2020;83(1):123-130. doi:10.1016/j.jaad.2020.03.004
AMA 11
Meah N, Wall D, York K, Bhoyrul B, Bokhari L, Sigall DA, et al. The Alopecia Areata Consensus of Experts (ACE) study: Results of an international expert opinion on treatments for alopecia areata. Jour. Amer. Acad. Derm.. 2020;83(1):123-130. doi:10.1016/j.jaad.2020.03.004
Chicago
Meah, N., Wall, D., York, K., Bhoyrul, B., Bokhari, L., Sigall, D. A., Bergfeld, W. F., Betz, R. C., Blume-Peytavi, U., Callender, V., and .... 2020. "The Alopecia Areata Consensus of Experts (ACE) study: Results of an international expert opinion on treatments for alopecia areata." Journal of the American Academy of Dermatology 83 (1): 123-130. https://doi.org/10.1016/j.jaad.2020.03.004
MLA 9
Meah, N., et al. "The Alopecia Areata Consensus of Experts (ACE) study: Results of an international expert opinion on treatments for alopecia areata." Journal of the American Academy of Dermatology, vol. 83, no. 1, 2020, pp. 123-130. doi:10.1016/j.jaad.2020.03.004.
PMID
32165196 ↗
추출된 의학 개체 (NER)
전체 NER 표 보기
| 유형 | 영어 표현 | 한국어 / 풀이 | UMLS CUI | 출처 | 등장 |
|---|---|---|---|---|---|
| 질환 | alopecia areata
|
원형 탈모증 | dict | 3 |
🏷️ 키워드 / MeSH 📖 같은 키워드 OA만
인용 관계
그래프 OA 노드: 7/8 (88%)
· 참조 0편 · 후속 7편
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