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Human Pancreatic Cancer Organoids.

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Cell proliferation 📖 저널 OA 95.8% 2023: 1/1 OA 2024: 2/2 OA 2025: 7/8 OA 2026: 12/12 OA 2023~2026 2026 p. e70210 OA Cancer Cells and Metastasis
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PubMed DOI OpenAlex 마지막 보강 2026-04-29
OpenAlex 토픽 · Cancer Cells and Metastasis Pancreatic and Hepatic Oncology Research Cancer, Stress, Anesthesia, and Immune Response

He A, Lin X, Qian X, Mu J, Tao Z, Gu J, Wang Y, Han T, Zhao H, Wang Y, Zhang J, Zhou Z, Xing L, Zhou C, Zhu D, Liu Z, Chen G, Zhou Q, Wang X, Zhao S, Liu X, Cao D, Yu B, Liu Z, Wang J, Niu G, Wei G, Chen M, Wang W, Kang X, Zhou J, Gong S, Xie Y, Zhang J, Kong X, Dong C, Zou Y, Tang L, Ma A, Xiong H, Liu X, Zhao T, Hao J, Xiao X, Xiang D

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This guideline establishes a comprehensive framework for the application of patient-derived pancreatic cancer organoids.

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APA Aina He, X L Lin, et al. (2026). Human Pancreatic Cancer Organoids.. Cell proliferation, e70210. https://doi.org/10.1111/cpr.70210
MLA Aina He, et al.. "Human Pancreatic Cancer Organoids.." Cell proliferation, 2026, pp. e70210.
PMID 42026891 ↗
DOI 10.1111/cpr.70210

Abstract

This guideline establishes a comprehensive framework for the application of patient-derived pancreatic cancer organoids. It outlines the stringent technical requirements and testing methods necessary to ensure high fidelity to the original tumor tissue, including morphological assessment, pathological biomarker expression (e.g., CK19, CK7), and genetic concordance (e.g., NRG1, KRAS). By standardizing protocols for in vitro culture, microbiological safety, and STR authentication, this consensus aims to ensure the reproducibility, safety, and stability of organoid models, thereby accelerating their integration into basic research, drug discovery, and precision medicine.

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