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27건 · 최신순-
An injectable photo-crosslinking silk hydrogel system with biphasic release of BTXA and 5-Fu promotes scarless wound healing.
Hypertrophic scarring is characterized by excessive dermal fibrosis and irregular collagen metabolism, mediated by fibroblasts derived from keloids. This condition typically arises from improper wound healing after deep burns, trauma, or su…
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Clinical evaluation of orthoplastic limb salvage protocol using anterolateral femoral free flap and kickstand fixation: A retrospective case-control study.
[PURPOSE] To evaluate the clinical outcome of orthoplastic limb salvage approach for the management of diabetic foot ulcers (DFUs). [METHODS] Patients with DFUs who received treatment at the Peking University Shenzhen Hospital between Janu…
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Management of Venous Thromboembolism (VTE) Complication Following Limb Replantation: A Report of Two Cases and Literature Review.
Venous thromboembolism (VTE) frequently occurs as a perioperative complication following major soft tissue reconstruction. Deep vein thrombosis (DVT) and pulmonary embolism (PE) represent the prevalent forms of VTE. Most of the symptoms man…
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Comparative effectiveness of 24-MHz high-frequency ultrasound versus ICG for preoperative lymphatic mapping in secondary lower limb lymphedema: A retrospective study.
[BACKGROUND] Preoperative lymphatic vessel mapping is essential for lymphaticovenous anastomosis (LVA). This study compared high-frequency ultrasound (HFUS) and indocyanine green (ICG) fluorescent lymphography in preoperative localization f…
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Three-dimensional facial soft-tissue changes after L-shaped reduction malarplasty: A pilot retrospective study.
[PURPOSE] Reduction malarplasty (RM) is a common facial contouring aesthetic procedure in East Asia. However, there is a lack of data on the postoperative changes in soft tissue and patient-reported outcomes. This retrospective study aimed …
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The impact of perceived stigma on appearance anxiety in postoperative rhinoplasty patients: A variable-centered and person-centered perspective.
Previous studies have highlighted that patients undergoing otolaryngological surgery often experience negative psychological outcomes, such as anxiety, depression, and social avoidance. However, little research has explored the relationship…
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Supramastoid Fascia as an Autologous Donor Site Alternative for Moderate Dorsal Augmentation: A Multicenter Prospective Study.
[BACKGROUND] Autologous fascia has been widely applied in rhinoplasty, yet prospective data on the supramastoid donor site remain scarce. This region provides a dense, pliable fascial layer with concealed scarring, potentially suitable for …
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Replantation of multiple fingertip amputations using super microsurgery: A case report and literature review.
[BACKGROUND] The fingertip amputation is an amputation type of the finger beyond the proximal nail fold. There is no vein available for anastomoses on the dorsal side of the finger, and the palmar vein of the finger is small and tightly att…
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Role of microsurgical techniques combined with Ilizarov techniques in limb salvage and functional reconstruction of thermal‑crush injuries of the hand: A case report.
The Ilizarov technology was proposed by Former Soviet orthopedic physician Ilizarov. It is a medical method to reconstruct missing tissues. Ilizarov technology combined with soft tissue stretching technology is of great significance in the …
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Study on botulinum toxin in dermatology from 2000 to 2023: A CiteSpace-based bibliometric analyses.
[OBJECTIVE] Using bibliometric methods, this study analyzed and summarized the current situation and development of the global application of botulinum toxin in dermatology. [METHODS] Literature published in the Web of Science Core Collect…
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Itaconic acid induces angiogenesis and suppresses apoptosis via Nrf2/autophagy to prolong the survival of multi-territory perforator flaps.
[BACKGROUND] Perforator flaps are widely used in hand microsurgery to reconstruct and repair soft tissue injuries. However, ischemia and subsequent ischemia-reperfusion injury may cause distal necrosis of the flap. Itaconic acid (IA) is a m…
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Ectopic multiple digit replantation salvage of hand torsion injury following anterolateral thigh perforator flap coverage.
Retrieval of four finger injury at proximal stump amputation with segmental injury along with soft tissue defect and impending compartment syndrome continues to be challenge for the surgeon. Immediate transplant considering temporary ectopi…
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The Comparative Effectiveness of Botulinum Toxin-A Injection Therapy Versus Augmentation Uretero-Enterocystoplasty for the Treatment of Lower Urinary Tract Dysfunction.
[PURPOSE] We investigated the effectiveness of intravesical botulinum toxin-A (BTX-A) injection therapy in patients with lower urinary tract dysfunction (LUTD) and upper urinary tract (UUT) deterioration and evaluated whether BTX-A injectio…
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Augmentation Uretero-enterocystoplasty Is an Effective Procedure in Protecting the Upper Urinary Tract Without Accelerating Deterioration of Renal Function.
[BACKGROUND] Augmentation uretero-enterocystoplasty (AUEC) provides a low-pressure urinary storage capsule that can preserve renal function in patients with lower urinary tract dysfunction for whom conservative treatments have failed. [OBJ…
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Glycan-modified cellular nanosponges for enhanced neutralization of botulinum toxin.
Botulinum toxin (BoNT) is a potent neurotoxin that poses a significant threat as a biowarfare weapon and a potential bioterrorist tool. Currently, there is a lack of effective countermeasures to combat BoNT intoxication in the event of a bi…
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Regionalized coverage of the totally degloved foot by a combination of "Boat sock" style free flap and skin graft.
[INTRODUCTION] To maximize the morpho-functional recovery on the totally degloved foot while not excessively introducing the technical complexity of microsurgery, we present a regionalized reconstruction, in which the highly functional subu…
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Activation of the NLRP3 inflammasome by RAC1 mediates a new mechanism in diabetic nephropathy.
[OBJECTIVE] Inflammation is central to the development and progression of diabetic nephropathy (DN). Although the exact mechanisms of inflammation in the kidney have not been well elucidated, pyrin domain containing 3 (NLRP3) inflammasome a…
- The incidence of capsular contracture after breast augmentation with the different prostheses.
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Algorithm for covering circumferential wound on limbs with ALTP or/and DIEP flaps based on chain-linked design and combined transplantation.
[INTRODUCTION] Coverage of circumferential wounds on limbs is a challenging reconstructive job. Here, we propose a skin flap-based algorithm to reconstruct circumferential wound with the chain-linked design and combined transplantation of A…
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Ras-Related C3 Botulinum Toxin Substrate 1 Combining With the Mixed Lineage Kinase 3- Mitogen-Activated Protein Kinase 7- c-Jun N-Terminal Kinase Signaling Module Accelerates Diabetic Nephropathy.
Ras-related C3 botulinum toxin substrate 1 (RAC1) activation plays a vital role in diabetic nephropathy (DN), but the exact mechanism remains unclear. In this study, we attempted to elucidate the precise mechanism of how RAC1 aggravates DN …
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Three-dimensional measurement and analysis of botulinum toxin A injection for improving the aesthetic appearance of upper lip.
This study evaluated the efficacy of botulinum toxin A (BTX A) in improving the aesthetic appearance of lips. Twenty-four outpatients with clinical evidence indicating decreased fullness of lips or gummy smile were selected and received BTX…
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Transcriptome analysis and functional identification of adipose-derived mesenchymal stem cells in secondary lymphedema.
[BACKGROUND] Secondary lymphedema is a common condition that affects patients with malignant tumors. Conservative treatments fail to provide lasting relief because they do not address the underlying pathological accumulation of excessive fa…
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Perturbation of epithelial apicobasal polarity by rhomboid family-1 gene overexpression.
The human rhomboid family (RHBDF)1 gene is highly expressed in breast cancer under clinical conditions but not in normal mammary gland tissues. Silencing the RHBDF1 gene in breast cancer xenograft tumors leads to inhibition of tumor growth.…
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The Application of the Acellular Dermal Matrix in the Correction of the Tear Trough Deformity.
[OBJECTIVE] The acellular dermal matrix (ADM) used in correcting the tear trough deformity has been reported, but there were only a few cases. The long-term effectiveness of ADM was not clear. We aim to discuss the technique and the effect …
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[Noninvasive monitoring of changes in the structure and function of masseter muscles after the injection of botulinum toxin type A].
[OBJECTIVE] To evaluate the effect and maintaining period of botulinum toxin A on the masseter muscles through noninvasive monitoring of changes in the structure and function of masseter muscle. [METHODS] We randomly selected 20 female pat…
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Assessment of three-dimensional high-definition visualization technology to perform microvascular anastomosis.
[BACKGROUND AND AIM] Traditional visualization techniques in microsurgery require strict positioning in order to maintain the field of visualization. However, static posturing over time may lead to musculoskeletal strain and injury. Three-d…
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Clinical analyses of clustered microcalcifications after autologous fat injection for breast augmentation.
[BACKGROUND] Autologous fat injection for breast augmentation has been disputed with regard to its complications for many years, especially regarding calcifications, most of which present with benign features. In previous studies, clustered…