Zhao H ⚠ 동명이인 가능성

[INTRODUCTION] The relationship between serum cytokine levels and immunologic non-response in people living with HIV (PLWH) receiving antiretroviral therapy (ART) remains inadequately characterized. This study aimed to comprehensively chara…

Immunotherapy has revolutionized cancer treatment, yet characterizing the spatial complexity of the tumor immune microenvironment remains a challenge. In this study, we established a comprehensive computational framework integrating multi-o…

[OBJECTIVE] To explore the current status of patient involvement in neoadjuvant treatment decision-making among individuals with locally advanced gastric cancer, and to further identify the factors influencing their level of participation. …

[BACKGROUND] Trastuzumab is the first-line therapy for human epidermal growth factor receptor-2 (HER2)-positive gastric cancer (GC). However, intrinsic and acquired resistance due to hyperactivation of intracellular signaling pathway such a…

[OBJECTIVE] The aim of this study was to investigate the diagnostic performance of the 2.5-dimensional (2.5D) ensemble deep learning (DL) model based on F-fuorodeoxyglucose (FDG) positron emission tomography (PET) images in predicting lymph…

Digital subtraction angiography (DSA) devices guide procedures across numerous diseases, performed on more than 100,000 patients daily worldwide. However, these procedures expose patients and healthcare providers to radiation, increasing th…

[BACKGROUND] Essential amino acids (EAAs) play a critical role in the metabolism of both tumor and immune cells, thereby potentially affecting tumor prognosis via multiple mechanisms. However, few studies have explored the impact of individ…

[BACKGROUND] Breast cancer (BC) is a common malignant tumor with high incidence and mortality rates. Mitophagy refers to a selective form of autophagy that is believed to be closely related to the occurrence and progression of BC. Identifyi…

Transforming growth factor-beta (TGF-β)/SMAD signaling exerts pleiotropic effects in cancer, orchestrating epithelial-mesenchymal transition (EMT), immune evasion, stemness, and therapeutic resistance. While canonically regarded as tumor-su…

Antiepileptic drugs (AEDs) are primarily indicated for controlling epileptic seizures. However, accumulating clinical evidence suggests that their benefits in patients with central nervous system (CNS) tumors extend beyond seizure managemen…

Therapeutic resistance is a major obstacle in cancer treatment, often leading to recurrence and death. SUMOylation is a dynamic and reversible process of post-translational modification through a strict enzyme cascade that regulates the mod…

[BACKGROUND] In blepharoplasty, a preaponeurotic fat pad has been considered to provide padding and structural support for the eyelid. In our practice, we have identified a dense fibrous membrane surrounding the preaponeurotic fat pad, whic…

[BACKGROUND] Nasal base depression is a frequent aesthetic concern in rhinoplasty, particularly in patients with midfacial retrusion. This study introduces a fascia transplantation technique to correct alar base (paranasal) depression and r…

[BACKGROUND] Atherosclerosis (AS) is a chronic inflammatory disease with a poor prognosis, and 5-methylcytosine (m5C) RNA modification plays a significant role in AS-induced cardio-cerebrovascular diseases (CCVDs). However, the effects of m…

Mutant KRAS activation occurs in most of pancreatic ductal adenocarcinoma (PDAC), which induce the sensitivity to ferroptosis of PDAC cells, but the underlying mechanism is still poorly understood. Here, we show how KRAS acts in signaling t…

[OBJECTIVES] Thyroid cancer (TC) is the most common endocrine malignancy, and bone metastasis (BM) is the second most common type of metastasis after lung. BM is associated with a poor prognosis; however, relevant research remains limited. …

[INTRODUCTION] Post-operative radiotherapy for prostate cancer requires precise contouring of the clinical target volume (CTV) to account for microscopic disease that is invisible in the image. However, the absence of the prostate gland and…

[BACKGROUND] This study aimed to investigate perioperative body composition changes and their clinical implications in patients undergoing radical gastric cancer surgery. [METHODS] Patient data are prospectively collected. Computed tomogra…

Air pollution, especially particulate matter (PM), is one of the most common risk factors for global burden of disease. However, its effect on the risk of digestive diseases is unclear. Herein, we attempt to explore this issue by reviewing …

[BACKGROUND] The association between Kyoto Encyclopedia of Genes and Genomes (KEGG) metabolic pathways and immunologic non-response among people living with HIV (PLHIV) on antiretroviral therapy (ART) is not well documented. This study aime…

Human epidermal growth factor receptor-2 (HER2) is an essential biomarker in oncology. It is highly expressed in many tumors, especially in breast cancer and gastric cancer, and is associated with the malignant progression of tumors. Trastu…

Gastric cancer, one of the leading causes of cancer-related mortality globally, faces challenges in treatment due to limitations in surgery, chemotherapy resistance, and high recurrence rates. Ferroptosis, an iron-dependent form of cell dea…

[RATIONALE AND OBJECTIVES] Accurate risk stratification in human epidermal growth factor receptor 2-positive surgically resectable advanced gastric cancer (HER2-p SRAGC) can strengthen monitoring for high-risk patients, allowing timely HER2…

Micro- and nanoplastics (MNPs) are ubiquitous contaminants increasingly recognized for their potential to adversely affect gastrointestinal (GI) health. This review provides a comprehensive overview regarding the impact of MNPs exposure on …

CagA, one of the key virulence factors of Helicobacter pylori, plays a significant role in H. pylori-associated gastric cancer by actively participating in neoplastic transformation. Among CagA variants, East Asian type CagA (CagA) bearing …

To explore the possible causal link between stable angina pectoris (SAP) and gastric cancer (GC) through Mendelian randomization analysis. We used data from genome-wide association studies (GWAS) statistical datasets, with SAP and GC screen…

[PURPOSE] This study aimed to gain an in-depth understanding of the psychological experience associated with the fear of cancer recurrence (FCR) among survivors of gastric cancer. Additionally, it sought to explore the triggering factors th…

Hepatocellular carcinoma (HCC) represents a major global health burden, ranking third as the leading cause of cancer-related mortality worldwide. This comprehensive review examines the substantial body of evidence linking modifiable lifesty…

Analysis of posttranslational modifications (PTM) of proteins can provide new insights, beyond those obtained from analysis of protein levels, for understanding the tumor microenvironment (TME). The characteristics of PTMs in immune cells, …