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Cost analysis and clinical outcomes of enhanced recovery after surgery for head and neck free flap reconstruction.
Head and neck reconstruction is among the most expensive types of surgery, requiring long operation time and hospital stays, with high complication rates. Enhanced recovery after surgery improves the quality of post-operative recovery. In t…
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Artificial Intelligence and Machine Learning in Reconstructive Microsurgery.
Artificial intelligence (AI) and machine learning (ML) technologies are transforming reconstructive microsurgery through data-driven approaches that enhance precision and standardize clinical workflows. These innovations address long-standi…
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Orthoplastic Approach to Extremity Reconstruction: A Paradigm Shift in Integrated Limb Salvage.
The orthoplastic approach to extremity reconstruction represents a paradigm shift in the management of complex limb injuries, integrating orthopedic and plastic surgery principles to optimize functional and aesthetic outcomes. This review e…
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Trophic Ulcer Elimination in Free Flap Reconstructed Weight-Bearing Plantar Defect: A Clinical Challenge.
Trophic ulceration represents a significant complication following free flap reconstruction of the plantar surface. Despite successful microvascular tissue transfer for posttraumatic defects, these ulcers develop due to biomechanical incomp…
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Largest Investigation of Branching Patterns of the Popliteal Artery.
Head and neck squamous cell carcinoma accounts for 4.5% of all new cancers diagnosed. A fibula free flap is often performed after tumor resection. Preoperative acknowledgment of the branching patterns of the popliteal artery is important to…
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Hemodynamic and Geometric Factors in Flow-Through Chain-Linked Double Free Flap Reconstruction: A Critical Analysis.
Complex head and neck defects requiring double free flap reconstruction present unique challenges in vascular design. Flow-through configurations, where one flap's arterial supply feeds a second flap, offer theoretical advantages but create…
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A Phase 2, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of OBI-858 for the Treatment of Moderate-to-Severe Glabellar Lines.
[INTRODUCTION] OBI-858 is a novel 760 kDa botulinum toxin type A complex produced by Clostridium botulinum, and currently under development for esthetic applications. This phase II clinical trial aimed to evaluate the efficacy, safety, and …
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Evolution of free flap reconstruction in the upper extremity: perspective from a tertiary plastic and reconstructive institution.
Soft tissue reconstruction of the upper extremity requires consideration of wound bed status, varied anatomic composition, future function and tissue match, whether in thickness, pliability or involvement of other tissue components. Of the …
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Supermicrosurgical lymphovenous anastomosis.
Lymphedema impairs patients' function and quality of life. Currently, supermicrosurgical lymphovenous anastomosis (LVA) is regarded as a significant and effective treatment for lymphedema. This article aims to review recent literature on th…
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Evolution and Diversity of Medial Sural Artery Perforator Flap for Hand Reconstruction.
The free medial sural artery perforator (MSAP) flap is a recently popularized flap. It has evolved from a composite myocutaneous flap to a pedicled perforator flap for lower limb reconstruction. It is also a versatile free perforator flap f…
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Free Fibula Flap for Congenital Pseudarthrosis of the Tibia: Indications and Challenges.
[BACKGROUND] Congenital pseudoarthrosis of the tibia (CPT) is a rare pathological disease associated with neurofibromatosis type 1 (NF1). It presents with tibial bowing and can progress into a nonhealing fracture. Treatment options include …
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Edge De-epithelialization for Reducing Pharyngocutaneous Fistula in Patch Free Flap Reconstructions for Salvage Total Laryngectomy Defects: A Case-Control Study.
[BACKGROUND] The leakage of saliva through the deep neck region from a pharyngocutaneous fistula could cause devastating complications, including vascular ruptures leading to mortality. While a partial pharyngoesophageal defect is created a…
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Three-dimensional facial soft-tissue changes after surgical orthodontics in different vertical facial types of skeletal Class III malocclusion: A retrospective study.
The study compared the soft-tissue response to hard-tissue movement among different Class III vertical facial types after orthognathic surgery (OGS). The study included 90 consecutive adult patients with skeletal Class III malocclusion who …
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Perfusion Dynamics during Secondary Flap Debulking with Liposuction.
[BACKGROUND] Lower extremity trauma often necessitates reconstruction with flap transfer. One of the reconstructive goals is a thin soft tissue coverage with appropriate contour. Therefore, a secondary debulking of the flap is usually perf…
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Total Surface Area of a Through-and-Through Oromandibular Defect Is Associated With Thromboembolic Events for Reconstruction With a Single Fibula Free Flap.
[BACKGROUND] Reconstruction of through-and-through composite oromandibular defects (COMDs) has been a challenge to plastic surgeons for decades. When using a free osteoseptocutaneous fibular flap, the skin paddle is restricted by the orient…
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Quantization of extraoral free flap monitoring for venous congestion with deep learning integrated iOS applications on smartphones: a diagnostic study.
[BACKGROUND] Free flap monitoring is essential for postmicrosurgical management and outcomes but traditionally relies on human observers; the process is subjective and qualitative and imposes a heavy burden on staffing. To scientifically mo…
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Outcome analysis of free flap reconstruction for head and neck cancer with intraoperative indocyanine green angiography.
[BACKGROUND] Intraoperative indocyanine green (ICG) angiography is used in free flap surgery to evaluate the patency of vessel anastomosis. This study evaluated the outcomes of intraoperative ICG angiography in free flap surgery for head an…
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Reliability of Postoperative Free Flap Monitoring with a Novel Prediction Model Based on Supervised Machine Learning.
[BACKGROUND] Postoperative free flap monitoring is a critical part of reconstructive microsurgery. Postoperative clinical assessments rely heavily on specialty-trained staff. Therefore, in regions with limited specialist availability, the f…
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Clinical Outcomes of Taiwanese Patients with Resected Oral Cavity Squamous Cell Carcinoma Who Underwent Reconstruction with Free Versus Local Flaps.
[BACKGROUND] We sought to compare the clinical outcomes of Taiwanese patients with resected oral cavity squamous cell carcinoma (OCSCC) who underwent reconstruction with free versus local flaps. [METHODS] From 2011 to 2017, we examined 864…
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Postoperative Sedation Duration as an Independent Risk Factor for Postoperative Pneumonia in Head and Neck Cancer Patients Undergoing Free Flap Reconstruction.
[OBJECTIVE] Patients who had reconstruction for head and neck cancer usually have long duration of postoperative sedation and intensive care. This is due to the complex nature of large-area soft tissue defect surgeries and upper respiratory…
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Free tissue transfers for reconstruction of weight-bearing heel defects: Flap selection, ulceration management, and contour revisions.
[BACKGROUND] Soft tissue defects in the weight-bearing heel represent a reconstructive challenge because of tissue complexity and lack of local/regional coverage. This study presents our reconstruction outcomes of different defect aetiologi…
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Real-time intraoperative computed tomography can accurize virtual surgical planning on the double-barrel fibular flap for mandibular reconstruction.
[UNLABELLED] Real-time intraoperative computed tomography created the accuracy of less than 1 mm deviation in virtual surgical planning double barrel fibular flap for mandibular reconstruction-the symbiosis of intelligent technology in a di…
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The Medial Sural Artery Perforator Flap in Lower Extremity Reconstruction.
Medial sural artery perforator (MSAP) flap is a thin, pliable, and versatile flap. It is a fasciocutaneous flap with chimeric design capacity. The donor site permits the synchronous harvesting of nonvascularized tendons and nerves. Free MSA…
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Functional Restoration in Lower Extremity Reconstruction.
Daily walking stance benefits the health, whereas lower extremity reconstruction aims to accomplish balanced walking and posture control. If local flap or tendon transfer cannot provide the basic function, microsurgical reconstruction is in…
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Cryopreserved allogenic vascular graft in free-flap reconstructive microsurgery: case report.
The use of cryopreserved allogenic vascular graft in reconstructive microsurgery has rarely been reported. Here, we report a case of lower extremity reconstruction using cryopreserved hepatic artery as the vein conduit. Postoperative flap p…
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Outcome of surgical-orthodontic treatment in hemifacial microsomia with and without early mandibular distraction osteogenesis.
The aim of this study was to compare the outcomes of surgical-orthodontic treatment between hemifacial microsomia (HFM) patients who had and had not undergone early mandibular distraction osteogenesis (DO). Twenty adult unilateral HFM patie…
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Comparison of the outcomes between free anteromedial thigh flap and anterolateral thigh flap in head and neck cancer reconstruction: Analysis of propensity-score-matched patient cohorts.
[BACKGROUND] The anterolateral thigh (ALT) flap is a workhorse flap in head and neck cancer reconstruction. The anteromedial thigh (AMT) flap was developed as a rescue or alternative flap whenever the ALT flap is not available; however, the…
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The Medial Sural Artery Perforator Flap: Lessons Learned from 200 Consecutive Cases.
[BACKGROUND] The medial sural artery perforator flap is a versatile option in reconstructive microsurgery. However, most reports of this flap have been limited by sample size. This study reviews the experience of a single large-volume cente…
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An overview of pain in Parkinson's disease.
Pain is a common non-motor symptom of Parkinson's disease (PD) and the prevalence of pain among PD patients varies because of the disease stage, co-morbidities, and evaluating tools. Risk factors for pain in PD include an early age of onset…
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Intra-arterial injection of human adipose-derived stem cells improves viability of the random component of axial skin flaps in nude mice.
[BACKGROUND] Skin flap necrosis is a common postoperative complication in reconstructive surgery. Recent evidence suggests that subcutaneously injected adipose-derived stem cells (ASCs) increase the viability of random skin flaps. Here, we …