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TL;DRIntra-articular therapy has advanced from palliation to mechanism-driven modulation and i-PRF and mesenchymal stem cells show the strongest disease-modifying signals; HA remains a safe backbone and carrier.

TL;DRA systematic review delineates the contrasting anatomical underpinnings of secondary cleft lip nasal deformity and elaborates on differentiated repair strategies, emphasizing symmetry restoration in unilateral deformitie…

[BACKGROUND] Columellar scarring remains an important aesthetic concern in open septorhinoplasty, and while multiple studies have compared absorbable and non-absorbable sutures, the specific effects of slowly absorbable polydioxanone (PDS) …

TL;DRSkinPlus-HYAL Implant Lidocaine was non-inferior to RESTYLANE Lidocaine for correction of moderate to severe NLFs and maintained efficacy through 48 weeks, supporting its use as an effective, safe option for facial aesth…

TL;DRPremixed intradermal BoNT-A with NCTF 135HA achieved superior wrinkle reduction, enhanced skin quality, and greater patient satisfaction than BoNT-A alone, with minimal downtime and an excellent safety profile.

TL;DRTo compare the safety and effectiveness of HASHA versus HAVLX for chin augmentation and correction of chin retrusion, a prospective, randomized, comparator-controlled, evaluator-blinded trial was conducted.

TL;DRThe novel PVA-HA filler demonstrates favorable physicochemical and biocompatibility properties, and provides clinically significant and safe outcomes in chin augmentation, representing a promising new option for soft tis…

[BACKGROUND] Acellular dermal matrix (ADM) is commonly used in implant-based breast reconstruction, but the optimal timing of ADM use in prepectoral two-stage reconstruction remains uncertain. [OBJECTIVES] We evaluated whether delaying ADM…

[BACKGROUND] The widespread use of hyaluronic acid (HA) dermal fillers has been accompanied by an increase in vascular complications, including ischemia and cutaneous necrosis. Although uncommon, filler-induced vascular compromise represent…

[BACKGROUND] Cell-free fat extract (CEFFE) has shown promising therapeutic effects on osteoarthritis (OA) in preclinical studies, but its clinical role remains unclear. [PURPOSE] To evaluate the safety and efficacy of intra-articular autol…

TL;DRHA injection was particularly useful for correcting deep superior sulcus deformity and was often preferred by patients seeking subtle volume restoration without surgery, and periocular fillers may sometimes be better tha…

Mandibular continuity defects following tumor resection or trauma present significant reconstructive challenges, particularly for subsequent dental rehabilitation. While the fibula free flap remains the gold standard, its limited vertical h…

TL;DRThe results of this investigation showed a statistically significant difference in the mean IOWA score across subgroups of patients belonging to different BMI categories undergoing OBLP via the transnasal approach, which…

TL;DRIt is indicated that both methods of applying the acellular dermal matrix (ADM) yield comparable outcomes, each with its own advantages and disadvantages.

TL;DRPrepectoral two-staged and DTI reconstruction have similar risk profiles, however, DTI may be more beneficial in the correctly identified patient, and is associated with higher rates of seromas and SSOs compared to DTI r…

[BACKGROUND] Red breast syndrome (RBS) is a self-limited, non-infectious erythema historically linked to acellular dermal matrices (ADMs) in breast reconstruction. Recent reports suggest a declining incidence, potentially related to ADM adv…

TL;DRThis study underscores the effectiveness of hyaluronidase in treating HA-related vascular complications, particularly when administered promptly, and supports the establishment of standardized treatment protocols to enha…

S. Y. Choi, Y. G. Koh, K. H. Yoo, H. S. Han, J. Seok, and B. J. Kim, "A Randomized, Participant- and Evaluator-Blinded, Matched-Pair, Prospective Study Comparing the Safety and Efficacy Between Polycaprolactone and Polynucleotide Fillers in…

TL;DRThese guidelines are not intended to be complete or exhaustive but may prove informative for aesthetic physicians and in-hospital specialists who are responsible for treating patients with HA filler–induced central retin…