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[OBJECTIVE] To review the mechanism of action, epidemiology, clinical efficacy, factors influencing treatment outcomes, and limitations of clomiphene citrate (CC). [METHODS] A systematic literature search was conducted using electronic dat…

[PURPOSE] Large vision-language models (VLMs), such as GPT-4.1 and GPT-4o, have shown strong potential in medical tasks. However, their application in lossless 3D medical image analysis is still underexplored. This study proposes a GPT-base…

[BACKGROUND] Bone cancer pain (BCP) is one of the most severe complications faced by cancer patients, with complex physiological and pathological mechanisms and unclear molecular characteristics. [METHODS] The BCP model was established by …

In the tumor microenvironment, tissue-resident macrophages (TRMs) promote malignant tumor progression, yet their tissue-specific heterogeneity and complex functions bring research challenges. This study analyzes the research status and tren…

Current nucleic detection techniques suffer from prolonged timelines, high false-positive amplification, and poor point-of-care testing (POCT) compatibility, especially for multiplex assays. This highlights an urgent need for efficient diag…

Cervical cancer (CC) is recognized as a significant health concern impacting females worldwide. The pathogenicity of CC is associated with human papillomavirus (HPV). Timely diagnosis, therefore, becomes imperative for reducing mortality an…

This study reports a structurally optimized exponential rolling circle amplification (ERCA)-lateral flow assay (LFA) platform that achieves ultrafast and ultrasensitive nucleic acid detection for cancer biomarker diagnosis. By engineering a…

TL;DRThis case highlights the potential role of local corticosteroid therapy in paraneoplastic vitelliform lesions secondary to metastatic melanoma, particularly when systemic immunosuppression is contraindicated.

[PURPOSE] Magnetic resonance (MR)-guided radiotherapy offers superior soft-tissue visualization, enabling more precise contouring and reduced toxicity. However, this workflow poses challenges for trainees. This study evaluated whether struc…

[OBJECTIVES] To explore how former breast cancer patients (BCPs) experience the daily-life impact of radiotherapy (RT) side effects and to examine how these narratives can inform the selection of patient stories for the BRASA patient decisi…

[OBJECTIVES] This study evaluated pre-post changes in readiness to engage in cancer screening among populations with low screening rates after using mobile problem-solving tools. Disseminating strategies for tool scale-up were examined. [M…

TL;DRCOF improves the sensitivity and specificity of the sensors, promising early and precise diagnosis of tumors, providing real-time data for subsequent treatments, and laying the 'perception' foundation for the tumor diagn…

[PURPOSE] To describe a case of mechanical eye globe penetration resulting in subretinal and vitreous hemorrhages and retinal tear that occurred immediately following a periorbital hyaluronic acid (HA) filler injection, and to outline acute…

[BACKGROUND] Music has been shown to reduce pain and anxiety during invasive procedures such as transrectal ultrasound-guided prostate biopsy, but its role during transperineal prostate biopsy (TPBx) has not yet been investigated. [OBJECTI…