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[OBJECTIVE] This study investigates serum metabolic profiles in breast cancer to identify diagnostic biomarkers and stage-specific metabolites, offering insights for clinical practice. [METHODS] Gas chromatography‒mass spectrometry (GC‒MS)…

[PURPOSE] To evaluate long-term reoperation risk after bilateral lateral rectus (BLR) recession for intermittent exotropia (IXT) in a paediatric cohort, and to identify the perioperative factors associated with recurrence and reoperation. …

[OBJECTIVES] Evaluate the gamma-glutamyl transpeptidase-to-albumin ratio (GAR) as a prognostic biomarker in acute myeloid leukemia (AML). [METHODS] We retrospectively analyzed the data of 162 patients with AML. Receiver operating character…

[BACKGROUND AND OBJECTIVES] The phase angle, which is associated with cellular health, has garnered increasing attention as a noninvasive and objective method for nutritional assessment. However, the association between malnutrition and pha…

[BACKGROUND] The initial response to radioiodine (³I) therapy is a critical determinant of prognosis in papillary thyroid carcinoma (PTC) patients undergoing therapeutic lateral neck dissection (LND). This study aimed to identify predictors…

[BACKGROUND] Ultrasound plays a crucial role in the preoperative evaluation of thyroid carcinoma and its extrathyroidal extension (ETE). This study aims to develop and validate a model integrating ultrasound radiomics and clinical factors f…

[AIM] To investigate the expression of Ly1 antibody-reactive clone (LYAR) in gastric cancer (GC) tissues and predict potential drugs targeting its sensitivity. [METHODS] We assessed the standardized mean difference (SMD) of LYAR mRNA expre…

Immune checkpoint inhibitors (ICIs) may cause immune-related adverse events (irAEs), ranging from mild to life-threatening. High-risk irAEs can lead to treatment discontinuation and higher mortality, though ICI-treated patients' death rate …

[BACKGROUND] The role of albumin-to-alkaline phosphatase ratio (AAPR) in predicting complications in elderly gastric cancer (GC) patients is unclear. [METHODS] This retrospective study included 358 elderly GC patients (≥60 years of age) wh…

[BACKGROUND] Colorectal cancer (CRC) represents a significant global health burden, requiring a deeper understanding of the molecular mechanisms that drive its progression. Circular RNAs (circRNAs) have appeared as crucial regulators in can…

[OBJECTIVE] This retrospective cohort study aimed to identify independent risk factors for early high-output stoma (HOS) following colorectal cancer (CRC) surgery and to construct and validate a predictive nomogram. [METHODS] Consecutive p…

[BACKGROUND] Transbronchial cryobiopsy (TBCB) is a minimally invasive technique that yields larger specimens than conventional transbronchial forceps biopsies (TBFB) and demonstrates superior diagnostic rates for interstitial lung diseases.…

[BACKGROUND] Chest wall invasion is a relatively kind of infrequent direct tumor extension in non-small cell lung cancer (NSCLC) with a poor survival outcome. Risk factors that impact overall survival (OS) and cancer-specific survival (CSS)…

[OBJECTIVE] To identify independent risk factors for micropapillary adenocarcinoma (MPA) in lung adenocarcinoma, a subtype often associated with poor prognosis, in order to support preoperative risk assessment and treatment planning. [METH…

[AIMS] Triple-negative breast cancer (TNBC) is aggressive and unresponsive to hormone therapy, drawing widespread attention to its treatment and prognosis. This study aimed to summarize the prognosis of early-stage TNBC and construct nomogr…

[BACKGROUND AND AIMS] Systemic inflammation is closely linked to the development and progression of various cancers, as well as poorer patient outcomes. The role of the c-reactive protein to albumin ratio (CAR) as a predictor of poor progno…

This paper introduces a continuous transient photoelectrochemical (PEC) biosensing strategy for rapid anti-vascular endothelial growth factor (VEGF) immobilization and quantification of VEGF in serum for colorectal cancer (CRC) diagnosis. A…

[BACKGROUND AND AIMS] Cancer-related factors can negatively affect nutritional status and impact disease trajectory. Prognostic biomarkers such as bioelectrical impedance-derived phase angle (PhA) may help identify patients at higher risk o…

TL;DRThis hypothesis-generating study demonstrates that baseline CECT radiomics shows promise for predicting chemotherapy response in pediatric lymphoma.

[BACKGROUND] This study aimed to investigate the role of serum N-terminal pro-B-type natriuretic peptide (NT-proBNP) and high-sensitivity cardiac troponin T (hs-cTnT) in predicting the occurrence and prognosis of symptomatic cardiovascular …