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52건 · 최신순-
Long-Term Outcomes and Natural Course of Giant Cerebral Arteriovenous Malformations (> 6 cm): Insights From a National Multicenter Propensity Score-Matched Cohort.
[OBJECTIVES] This study evaluated the natural history of giant cerebral arteriovenous malformations (AVMs) over 6 cm and compared long-term outcomes of interventional treatment versus conservative management. [MATERIALS AND METHODS] Patien…
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Medial Epicanthoplasty: A Modified Inverted Z-Plasty Technique to Create Ethnic Appropriate Medial Canthal Configuration.
[BACKGROUND] The medial epicanthal fold is a common anatomical feature in Asian populations, often coexisting with single eyelid configurations. Epicanthoplasty, combined with blepharoplasty, is a standard cosmetic procedure to create a lar…
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Clinical comparison of flow diversion and microsurgery for retreatment of intracranial aneurysms.
[BACKGROUND] The goal of aneurysm retreatment is effective, durable obliteration. Flow diversion (FD) and microsurgical clipping generally represent two aneurysm treatment options with high obliteration rates. However, their relative effica…
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Iliac crest free flap versus fibula free flap for mandibular reconstruction: Cost-effectiveness analysis in a Chinese population.
Mandibular reconstruction is vital in oral and maxillofacial surgery to restore aesthetics and function after tumor resection or trauma. The iliac crest-free flap (ICFF) and fibula-free flap (FFF) are widely used, but their cost-effectivene…
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Infratentorial brain arteriovenous malformations: natural history and long-term outcome-a propensity score matched analysis using nationwide multicenter prospective registry data.
[OBJECTIVES] This study evaluated the natural history of infratentorial brain arteriovenous malformations (AVMs) and compared long-term outcomes of intervention versus conservative management. [MATERIALS AND METHODS] Infratentorial AVMs fr…
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Clinical characteristics and management for intracranial serpentine aneurysms: a 12-year single-center retrospective analysis of 51 patients.
[BACKGROUND] Serpentine aneurysms, a rare and complex type of intracranial aneurysm, pose significant treatment challenges. The natural course of these aneurysms and the definitive interventional treatment effect remains elusive. This study…
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Vascularized iliac crest flap with double musculocutaneous skin islands for reconstruction of composite buccal and mandibular defects after gingival squamous cell carcinoma resection: A case report.
Mandibular gingival squamous cell carcinoma (GSCC) is a challenging malignancy often requiring extensive surgical resection and complex reconstruction. This study presents a 69-year-old male with left mandibular GSCC, treated with segmental…
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Learning curve and embolisation strategy in single-stage surgery combined embolisation and microsurgery for brain arteriovenous malformations: results from a nationwide multicentre prospective registry study.
[OBJECTIVE] Single-stage surgery combining embolisation and microsurgery has been increasingly used as a stand-alone procedure to cure complex AVMs. This study aimed to investigate the learning curve and embolisation strategy for single-sta…
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Nonsurgical Therapies for Spastic Cerebral Palsy: A Network Meta-Analysis.
[CONTEXT] Spastic cerebral palsy (SCP) presents daily challenges because of spasms, impacting motor function. Although multiple nonsurgical therapies exist, their comparative efficacy remains uncertain. [OBJECTIVE] To compare the effective…
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Calreticulin-driven immunogenic cell death promotes osteoclast differentiation and osteoarthritis progression via the LRP1/Rac1 signaling.
Aberrant osteoclast activation in subchondral bone is a hallmark of osteoarthritis (OA). This study identifies calreticulin (CALR), a key immunogenic cell death (ICD) marker, as a critical regulator of osteoclast differentiation and OA path…
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Prognostic Modeling and Clinical Evaluation of Adverse Factors in Postherpetic Neuralgia Treated With Botulinum Toxin Type A: A Randomized Controlled Trial.
[OBJECTIVES] This study aims to evaluate the efficacy of Botulinum toxin type A (BTX-A) in patients with postherpetic neuralgia (PHN) and to identify key prognostic factors associated with treatment response. [METHODS] This prospective, ra…
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Application of absorbable internal fixation system in secondary rhinoplasty of patients with unilateral cleft lip.
[BACKGROUND] Postoperative nasal asymmetry is a common secondary deformity following correction of unilateral cleft lip, with insufficient structural reinforcement along the nasal midline representing a key etiological factor. [PURPOSE] To…
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Comparison of conservative management, microsurgery only, and microsurgery with preoperative embolization for unruptured arteriovenous malformations: A propensity score weighted prospective cohort study.
[AIMS] To compare the efficacy and deficiency of conservative management (CM), microsurgery (MS) only, and microsurgery with preoperative embolization (E + MS) for unruptured arteriovenous malformations (AVMs). [METHODS] We prospectively i…
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Association of hemorrhage-to-treatment time with outcomes in patients with brainstem cavernous malformations: a nationwide cohort study.
[BACKGROUND] Brainstem cavernous malformations (BSCMs) often present with haemorrhage, but the optimal timing for microsurgical intervention remains unclear. This study aims to explore how intervention timing relates to neurological outcome…
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Blood-Blister Aneurysms of the Internal Carotid Artery in Tibetan and Han Populations : A Retrospective Observational Study.
[OBJECTIVE] Blood-blister aneurysms (BBAs) of the internal carotid artery (ICA) are challenging lesions with high morbidity and mortality rates. Although research on BBAs is well documented in different populations, the study of BBAs in the…
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A comprehensive analysis of patients with cerebral arteriovenous malformation with headache: assessment of risk factors and treatment effectiveness.
[BACKGROUND] Due to the high mortality and disability rate of intracranial hemorrhage, headache is not the main focus of research on cerebral arteriovenous malformation (AVM), so research on headaches in AVM is still scarce, and the clinica…
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Enhancing the Extent of Resection in Glioma Surgery Through the Integration of Intraoperative Contrast-Enhanced Ultrasound and Fluorescein Sodium.
[OBJECTIVE] Due to the infiltrative nature and high local recurrence of gliomas, particularly high-grade gliomas, gross total resection (GTR) of a tumor is the first critical step in treatment. This study aimed to determine whether the inte…
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Development and Validation of a Supplementary Grading Scale for Outcomes of Brainstem Cavernous Malformations.
[BACKGROUND] Surgical risk assessment is intriguing for clinical decision-making of brainstem cavernous malformation (BSCM) treatment. While the BSCM grading scale, encompassing size, developmental venous anomaly, crossing axial midpoint, a…
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Botulinum toxin type A injection combined with biofeedback in the treatment of spastic pelvic floor syndrome.
[BACKGROUND] Spastic pelvic floor syndrome (SPFS) is a refractory pelvic floor disease characterized by abnormal (uncoordinated) contractions of the external anal sphincter and puborectalis muscle during defecation, resulting in rectal empt…
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Single Mini-incisional Blepharoplasty with the Orbicularis-Orbital Septum Fixation Technique for the Creation of a Natural Double Eyelid.
[BACKGROUND] Mini-incisional double-eyelid blepharoplasty has increasingly gained popularity in oriental populations. Moreover, many related studies have made a detailed technical introduction to this topic. This study aims to introduce a s…
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Long-term outcomes of microsurgery and stereotactic radiosurgery as the first-line treatment for arteriovenous malformations: a propensity score-matched analysis using nationwide multicenter prospective registry data.
[BACKGROUND] This study aimed to compare the risk and benefit profile of microsurgery (MS) and stereotactic radiosurgery (SRS) as the first-line treatment for unruptured and ruptured arteriovenous malformations (AVMs). [MATERIALS AND METHO…
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Current perspectives and trends in the treatment of brain arteriovenous malformations: a review and bibliometric analysis.
[BACKGROUND] Currently, there is a lack of intuitive analysis regarding the development trend, main authors, and research hotspots in the field of cerebral arteriovenous malformation treatment, as well as a detailed elaboration of possible …
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Vitamin D Receptor Activation Targets ROS-Mediated Crosstalk Between Autophagy and Apoptosis in Hepatocytes in Cholestasic Mice.
[BACKGROUND & AIMS] Observational epidemiologic studies have associated vitamin D deficiency with cholestasis. We reported previously that activation of the vitamin D/vitamin D receptor (VDR) axis in cholangiocytes mitigates cholestatic liv…
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Small-incision, mini-dissection, orbicularis-preservation, and orbicularis-levator aponeurosis fixation technique: A modified partial-incision double-eyelid blepharoplasty.
[BACKGROUND] The partial-incision double-eyelid surgery remains a popular esthetic procedure in Asia, most of the previous partial-incision double-eyelid operations involved resection of the pretarsal orbicular muscle, resulting in a depres…
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Sunken Upper Eyelid Deformity Correction by Orbital Fat Pad Repositioning and Orbicularis Oculi Muscle Folding in Blepharoplasty.
[BACKGROUND] Sunken upper eyelid deformity results in an aged and unnatural appearance and is common among Asians along with the single eyelid. The upper eyelid volume restoration is as important as the creation of a supratarsal fold for pa…
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[Evaluating the efficiency of endoscope-assisted septo-rhinoplasty via intranasal approach].
To observe the functional and esthetic results of endoscope-assisted septo-rhinoplasty via intranasal approach. The clinical data of 12 patients with septal deviation and nasal deformity in the University of Hong Kong-Shenzhen Hospital fro…
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Long-term outcomes of Spetzler-Martin grade IV and V arteriovenous malformations: a single-center experience.
[OBJECTIVE] This study aimed to explore whether intervention can benefit Spetzler-Martin (SM) grade IV-V arteriovenous malformations (AVMs). [METHODS] Eighty-two patients with SM grade IV-V AVMs were retrospectively reviewed from 2015 to 2…
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Multimodality treatment for brain arteriovenous malformation in Mainland China: design, rationale, and baseline patient characteristics of a nationwide multicenter prospective registry.
[BACKGROUND] Brain arteriovenous malformation (AVM) is an important cause of hemorrhagic stroke in young adults, which can lead to severe neurological impairment. The registry of Multimodality treatment for brain ArTeriovenous malformation …
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An alternative surgical technique for varicoceles: a preliminary experience of the microsurgical spermatic (distal end)-inferior or superficial epigastric vein anastomosis in symptomatic varicoceles associated with perineal pain.
Many therapies are effective in treating varicoceles, including dilation of the pampiniform plexus in males. The most common method of treatment is varicocelectomy. We aimed to assess an alternative technique (microsurgical spermatic [dista…
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A propensity score-matched study on the short-term outcome of ruptured blood blister-like aneurysm treated by microsurgery or endovascular surgery: a single-center study of 155 cases.
Treating blood blister-like aneurysms (BBA) is a major neurosurgical challenge. Whether endovascular repair serves as a better strategy than microsurgery remains controversial. We aim to perform a propensity score-matched (PSM) retrospectiv…