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Intra-articular therapies for synovial joint dysfunction: a comprehensive integrative review.
TL;DRIntra-articular therapy has advanced from palliation to mechanism-driven modulation and i-PRF and mesenchymal stem cells show the strongest disease-modifying signals; HA remains a safe backbone and carrier.
FULLTEXT: Cellular Reprogramming randomized -
Comparison of Polydioxanone and Polypropylene Sutures in Columellar Incision Closure: A Prospective Randomized Clinical Trial.
[BACKGROUND] Columellar scarring remains an important aesthetic concern in open septorhinoplasty, and while multiple studies have compared absorbable and non-absorbable sutures, the specific effects of slowly absorbable polydioxanone (PDS) …
FULLTEXT: Cellular Reprogramming randomized -
Safety and Effectiveness of a Crosslinked Hyaluronic Acid Filler in Korean Patients for the Correction of Nasolabial Folds: A Randomized, Patient- and Evaluator-Blinded, Paired Study.
TL;DRSkinPlus-HYAL Implant Lidocaine was non-inferior to RESTYLANE Lidocaine for correction of moderate to severe NLFs and maintained efficacy through 48 weeks, supporting its use as an effective, safe option for facial aesth…
FULLTEXT: Cellular Reprogramming randomized -
Streamlined Facial Rejuvenation: A Randomized Split-Face Trial of Premixed Intradermal Botulinum Toxin Type A and Hyaluronic Acid Biorevitalization.
TL;DRPremixed intradermal BoNT-A with NCTF 135HA achieved superior wrinkle reduction, enhanced skin quality, and greater patient satisfaction than BoNT-A alone, with minimal downtime and an excellent safety profile.
FULLTEXT: Cellular Reprogramming randomized -
Safety and Effectiveness of Two High-G' Soft Tissue Fillers for Chin Augmentation: A Prospective, Randomized, Comparator-Controlled, Evaluator-Blinded Trial.
TL;DRTo compare the safety and effectiveness of HASHA versus HAVLX for chin augmentation and correction of chin retrusion, a prospective, randomized, comparator-controlled, evaluator-blinded trial was conducted.
FULLTEXT: Cellular Reprogramming randomized -
Effectiveness and Safety of a Polyvinyl Alcohol Microsphere and Hyaluronic Acid Suspension for Chin Augmentation: A Randomized Controlled Trial and Multidisciplinary Study.
TL;DRThe novel PVA-HA filler demonstrates favorable physicochemical and biocompatibility properties, and provides clinically significant and safe outcomes in chin augmentation, representing a promising new option for soft tis…
FULLTEXT: Cellular Reprogramming randomized -
Advanced Regenerative Drainage and Immunomodulatory Protocol for Dermal Filler-Induced Skin Necrosis: A Prospective Clinical Case Series.
[BACKGROUND] The widespread use of hyaluronic acid (HA) dermal fillers has been accompanied by an increase in vascular complications, including ischemia and cutaneous necrosis. Although uncommon, filler-induced vascular compromise represent…
FULLTEXT: Cellular Reprogramming randomized -
Safety and Efficacy of Intra-articular Cell-Free Fat Extract Injection in Patients With Symptomatic Knee Osteoarthritis.
[BACKGROUND] Cell-free fat extract (CEFFE) has shown promising therapeutic effects on osteoarthritis (OA) in preclinical studies, but its clinical role remains unclear. [PURPOSE] To evaluate the safety and efficacy of intra-articular autol…
FULLTEXT: Cellular Reprogramming randomized -
Experimental Histopathological Comparison of Fresh Frozen Allograft and Autograft Cartilage.
TL;DRFFCA preserves structural integrity and integrates with surrounding tissue but exhibits lower cellular viability than autografts, while it may represent a useful alternative in rhinoplasty, further studies are required t…
FULLTEXT: Cellular Reprogramming randomized -
From Bench to Bedside: A Pilot Clinical Study on NANOTEX Bone Graft for Fibula Onlay Augmentation in Mandibular Reconstruction.
Mandibular continuity defects following tumor resection or trauma present significant reconstructive challenges, particularly for subsequent dental rehabilitation. While the fibula free flap remains the gold standard, its limited vertical h…
FULLTEXT: Cellular Reprogramming randomized -
Improvement in Temple Hollowing with VYC-20L Hyaluronic Acid Filler: A Multicenter Randomized Controlled Trial of Safety and Effectiveness.
FULLTEXT: Cellular Reprogramming randomized
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Hyaluronidase Protocol in Management of Hyaluronic Acid Filler-Related Vascular Complications: A Systematic Review and Meta-Analysis.
TL;DRThis study underscores the effectiveness of hyaluronidase in treating HA-related vascular complications, particularly when administered promptly, and supports the establishment of standardized treatment protocols to enha…
FULLTEXT: Cellular Reprogramming randomized -
Comparative Evaluation of Hyaluronic Acid and Agarose Gel as Dermal Fillers: An Experimental Study on Volume Retention and Histological Response.
TL;DRAG demonstrated greater structural stability and a more robust cellular response compared to HA, suggesting that AG may offer a more durable and biologically active alternative to HA in subcutaneous filler applications.
FULLTEXT: Cellular Reprogramming randomized -
RETRACTION: A Randomized, Participant- and Evaluator-Blinded, Matched-Pair, Prospective Study Comparing the Safety and Efficacy Between Polycaprolactone and Polynucleotide Fillers in the Correction of Crow's Feet.
S. Y. Choi, Y. G. Koh, K. H. Yoo, H. S. Han, J. Seok, and B. J. Kim, "A Randomized, Participant- and Evaluator-Blinded, Matched-Pair, Prospective Study Comparing the Safety and Efficacy Between Polycaprolactone and Polynucleotide Fillers in…
FULLTEXT: Cellular Reprogramming randomized -
Management of Visual Loss Following Hyaluronic Acid Filler Injections: An Algorithm-based Approach.
TL;DRThese guidelines are not intended to be complete or exhaustive but may prove informative for aesthetic physicians and in-hospital specialists who are responsible for treating patients with HA filler–induced central retin…
FULLTEXT: Cellular Reprogramming randomized -
Hyaluronic acid fillers in systemic sclerosis and localized scleroderma: A systematic review.
TL;DRHA fillers appear to be a safe and minimally invasive procedure for addressing both functional and aesthetic concerns of patients with SSc or morphea.
FULLTEXT: Cellular Reprogramming randomized -
Surgical vs Non-surgical Chin Augmentation: A Systematic Review of Techniques Satisfaction, and Complications.
TL;DRBoth surgical and non-surgical chin augmentation techniques can achieve favorable aesthetic outcomes and high patient satisfaction, but with distinct durability and risk profiles.
FULLTEXT: Cellular Reprogramming randomized -
Efficacy and Safety of New Hyaluronic Acid Filler for Nasolabial Fold Correction: A Double-Blind, Randomized Trial.
TL;DRCUREA® is comparable to Juvederm® in NLF correction and safety profiles, and its efficacy lasts up to 24 weeks, and its efficacy within the predefined non-inferiority margin.
FULLTEXT: Cellular Reprogramming randomized -
A Multicenter, Randomized, Evaluator-Blind, No-Treatment Controlled Study of YVOIRE Y-Solution 720: A Volumizing Hyaluronic Acid Filler for Midface Volume Deficit.
TL;DRThis study supports that YVOIRE Y-Solution 720 is an effective and safe option for midface volume augmentation and demonstrates the statistically significant improvement of YYS7720 in midface augmentation.
FULLTEXT: Cellular Reprogramming randomized -
Exploring successful treatments for upper eyelid retraction in thyroid eye disease: A scoping review.
TL;DRFuture prospective comparative studies incorporating both functional and aesthetic outcomes are essential to establish evidence-based, phase-specific treatment strategies for GAUER, and synthesizes outcomes, and identifi…
FULLTEXT: Cellular Reprogramming randomized