Alopecia areata and health-related quality of life: a systematic review and meta-analysis.
💡 한 문장 핵심
원형탈모증과 건강 관련 삶의 질: 체계적 문헌고찰 및 메타분석.
메타분석
5/5 보강
TL;DR
No systematic review has yet evaluated the available evidence on health‐related quality of life (HRQOL) in alopecia areata (AA).
PICO 자동 추출 (휴리스틱, conf 2/4)
유사 논문P · Population 대상 환자/모집단
환자: AA was 6·3 (95% confidence interval 5·6-7·1)
I · Intervention 중재 / 시술
추출되지 않음
C · Comparison 대조 / 비교
추출되지 않음
O · Outcome 결과 / 결론
Several generic and dermatology-specific HRQOL instruments have been used, but no validation studies have confirmed their applicability in AA. The newly developed AA-specific measures seem very promising; however, a more extensive assessment of validity and reliability is needed.
📑 코퍼스 인용 관계
· 인용됨 76
📑 인용한 논문 (6) ▾
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- Stem cell-based therapies for alopecia areata: a narrative review. Stem cell research & therapy · 2026
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연도별 인용 (2016–2026) · 합계 230
OpenAlex 토픽 ·
Hair Growth and Disorders
Facial Rejuvenation and Surgery Techniques
Skin and Cellular Biology Research
🇰🇷 한글 요약 🌐 Abstract
【연구 목적】
원형 탈모증(alopecia areata, AA) 환자의 건강관련 삶의 질(health-related quality of life, HRQOL)에 대한 기존 근거를 체계적으로 평가하고 메타분석한 최초의 연구입니다.
【방법】
1946년~2014년 12월까지 6개 데이터베이스를 검색해 성인 AA 환자 총 2,530명을 포함한 21편의 연구를 선정했고, 무작위효과 모형(random-effects model)으로 데이터를 통합 분석했습니다. 주요 측정도구는 DLQI(피부과 삶의 질 지수, n=8)와 SF-36(n=7)이었습니다.
【주요 결과】
AA 환자의 통합 DLQI 평균은 6.3점(95% CI 5.6–7.1)으로 삶의 질 저하가 확인됐고, SF-36에서는 연령·성별 대조군 대비 감정역할·정신건강·활력 영역이 유의하게 저하됐습니다(P<0.001). 가발 착용은 긍정적, 두피(scalp) 침범·불안·우울은 부정적 영향을 미쳤습니다.
【임상적 시사점 (성형외과 의사 관점)】
AA 환자는 특히 정신건강 측면에서 삶의 질 손상이 크므로, 모발이식·두피 시술 상담 시 미용적 결과뿐 아니라 불안·우울 등 심리적 부담을 함께 평가하는 것이 중요합니다. 가발 등 외형 보완이 삶의 질 개선에 기여하므로 치료 옵션 설명 시 적극 안내할 가치가 있습니다.
[BACKGROUND] No systematic review has yet evaluated the available evidence on health-related quality of life (HRQOL) in alopecia areata (AA).
[OBJECTIVES] To conduct a systematic review and meta-analysis of HRQOL studies among patients diagnosed with AA.
[METHODS] A systematic search was performed for papers published between 1946 and 15 December 2014 in Medline, Embase, Web of Science, CINAHL, PsycINFO and the Cochrane Library. Random-effects meta-analyses were conducted to pool data.
[RESULTS] Twenty-one studies were included, representing a total of 2530 adult patients with AA. Of the 14 different HRQOL measures used in the studies, Dermatology Life Quality Index (DLQI; n = 8) and SF-36 (n = 7) were the most common. Three AA-specific HRQOL instruments were identified: Alopecia Areata Quality of Life Index, Alopecia Areata Quality of Life and Alopecia Areata Symptom Impact Scale. The mean pooled DLQI score of patients with AA was 6·3 (95% confidence interval 5·6-7·1). Comparing age- and sex-matched controls, the meta-analysis of SF-36 studies revealed significantly reduced HRQOL across the role-emotional, mental health and vitality domains (P < 0·001). Wearing a wig had a positive impact, while scalp involvement, anxiety and depression had a negative impact on HRQOL. Conflicting results were found regarding the association between HRQOL and age, sex, marital status and disease duration.
[CONCLUSIONS] Patients with AA experience significant impairment in HRQOL, especially in the area of mental health. Several generic and dermatology-specific HRQOL instruments have been used, but no validation studies have confirmed their applicability in AA. The newly developed AA-specific measures seem very promising; however, a more extensive assessment of validity and reliability is needed.
[OBJECTIVES] To conduct a systematic review and meta-analysis of HRQOL studies among patients diagnosed with AA.
[METHODS] A systematic search was performed for papers published between 1946 and 15 December 2014 in Medline, Embase, Web of Science, CINAHL, PsycINFO and the Cochrane Library. Random-effects meta-analyses were conducted to pool data.
[RESULTS] Twenty-one studies were included, representing a total of 2530 adult patients with AA. Of the 14 different HRQOL measures used in the studies, Dermatology Life Quality Index (DLQI; n = 8) and SF-36 (n = 7) were the most common. Three AA-specific HRQOL instruments were identified: Alopecia Areata Quality of Life Index, Alopecia Areata Quality of Life and Alopecia Areata Symptom Impact Scale. The mean pooled DLQI score of patients with AA was 6·3 (95% confidence interval 5·6-7·1). Comparing age- and sex-matched controls, the meta-analysis of SF-36 studies revealed significantly reduced HRQOL across the role-emotional, mental health and vitality domains (P < 0·001). Wearing a wig had a positive impact, while scalp involvement, anxiety and depression had a negative impact on HRQOL. Conflicting results were found regarding the association between HRQOL and age, sex, marital status and disease duration.
[CONCLUSIONS] Patients with AA experience significant impairment in HRQOL, especially in the area of mental health. Several generic and dermatology-specific HRQOL instruments have been used, but no validation studies have confirmed their applicability in AA. The newly developed AA-specific measures seem very promising; however, a more extensive assessment of validity and reliability is needed.
- 표본수 (n) 8
- 연구 설계 systematic review
【연구 목적】 원형 탈모증(alopecia areata, AA) 환자의 건강관련 삶의 질(health-related quality of life, HRQOL)에 대한 기존 근거를 체계적으로 평가하고 메타분석한 최초의 연구입니다.
APA 7
Rencz, F., L, G., M, P., N, W., Baji, P., & Brodszky, V. (2016). Alopecia areata and health-related quality of life: A systematic review and meta-analysis.. The British journal of dermatology, 175(3), 561-71. https://doi.org/10.1111/bjd.14497
Vancouver
Rencz F, L G, M P, N W, Baji P, Brodszky V. Alopecia areata and health-related quality of life: a systematic review and meta-analysis. Brit. jour. derm.. 2016;175(3):561-71. doi:10.1111/bjd.14497
AMA 11
Rencz F, L G, M P, N W, Baji P, Brodszky V. Alopecia areata and health-related quality of life: a systematic review and meta-analysis. Brit. jour. derm.. 2016;175(3):561-71. doi:10.1111/bjd.14497
Chicago
Rencz, F., L, G., M, P., N, W., Baji, P., and Brodszky, V.. 2016. "Alopecia areata and health-related quality of life: a systematic review and meta-analysis." The British journal of dermatology 175 (3): 561-71. https://doi.org/10.1111/bjd.14497
MLA 9
Rencz, F., et al. "Alopecia areata and health-related quality of life: a systematic review and meta-analysis." The British journal of dermatology, vol. 175, no. 3, 2016, pp. 561-71. doi:10.1111/bjd.14497.
PMID
26914830 ↗
추출된 의학 개체 (NER)
전체 NER 표 보기
| 유형 | 영어 표현 | 한국어 / 풀이 | UMLS CUI | 출처 | 등장 |
|---|---|---|---|---|---|
| 질환 | alopecia areata
|
원형 탈모증 | dict | 5 | |
| 질환 | alopecia areata
|
원형 탈모증 | dict | 5 | |
| 질환 | alopecia areata
|
원형 탈모증 | dict | 5 | |
| 해부 | scalp
|
두피 | dict | 1 | |
| 해부 | scalp
|
두피 | dict | 1 | |
| 해부 | scalp
|
두피 | dict | 1 |
🏷️ 키워드 / MeSH 📖 같은 키워드 OA만
인용 관계
그래프 OA 노드: 8/8 (100%)
· 참조 0편 · 후속 8편
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