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Comparative efficacy of intralesional therapies for keloid scars: a network meta-analysis.
TL;DRIt is indicated that combination therapies, most notably 5-FU’s+ corticoids’+ YAG:Laser, offer the greatest benefit, and data for novel agents suggest potential, while data for novel agents suggest potential.
FULLTEXT: parallel database design randomized randomized -
A prospective study of hair transplantation combined with concentrated growth factors for the treatment of androgenetic alopecia.
TL;DRCGF-assisted FUE significantly improved hair density and terminal hair ratio compared with FUE alone, with favorable safety and high patient satisfaction.
FULLTEXT: parallel database design randomized randomized -
Decreased utilization of component separation techniques over time in complex abdominal wall reconstruction following introduction of preoperative botulinum toxin A.
TL;DRFollowing the introduction of BTA, utilization of CST decreased and was accompanied by a reduction in wound morbidity.
FULLTEXT: parallel database design randomized randomized -
Chondrocyte proliferation without inflammation underlies botulinum toxin-induced mandibular enthesis bone hypertrophy in rats.
TL;DRBTX-related muscle atrophy of masticatory muscle induced chondrocyte proliferation at enthesis without inflammation process and BTX-related muscle atrophy of masticatory muscle induced chondrocyte proliferation at enthes…
FULLTEXT: parallel database design randomized randomized -
Tranexamic Acid in Reconstructive Microsurgery: A Systematic Review and Meta-Analysis.
Tranexamic acid (TXA) has gained popularity across various surgical specialties for reducing perioperative blood loss. However, its role in microsurgery remains underexplored, likely due to concerns that TXA may increase the risk of thrombo…
FULLTEXT: parallel database design randomized randomized -
Electromyography-guided botulinum toxin injections in provoked vestibulodynia: a randomized double-blind placebo-controlled clinical trial.
TL;DROnabotulinum toxin A injections were effective on the pain, quality of life and sexual functions of the patients and it is suggested that muscular dysfunction is a key element of vestibulodynia pain.
FULLTEXT: parallel database design randomized randomized -
Evaluation of the ultrasonography-guidance for botulinum toxin type a injection into lateral pterygoid muscle in patients with TMJ anterior disc displacement with reduction.
TL;DRThe findings suggest that ultrasound-guided BTX-A injection into the LPM is a safe and effective treatment for ADDwR, enhancing joint function and symptom relief, although larger randomized studies are recommended.
FULLTEXT: parallel database design randomized randomized -
Breast plastic surgery in perimenopausal and postmenopausal women: Menopause-informed counseling on screening, safety, and long-term breast health.
[OBJECTIVES] To synthesize evidence on breast plastic surgery in peri- and postmenopausal women and provide menopause-informed guidance on surgical safety, cancer screening, and long-term implant surveillance. [STUDY DESIGN] Narrative revi…
FULLTEXT: parallel database design randomized randomized -
Red and near-infrared photobiomodulation for burn, hypertrophic, and post-surgical scars: a scoping review of clinical trials.
[PURPOSE] Scars may lead to pain, pruritus, functional impairment, and cosmetic concern despite standard therapies. Photobiomodulation (PBM) delivered by light-emitting-diode (LED) or low-level laser therapy (LLLT) has emerged as a non-inva…
FULLTEXT: parallel database design randomized randomized -
GLP-1 Receptor Agonist Use and Wound Outcomes After Free Flap Breast Reconstruction.
Background Glucagon-like peptide-1 receptor agonists (GLP-1s) are increasingly used for glycemic control and weight loss, but their impact on surgical wound complications remains unclear. Some studies suggest GLP-1s reduce complications suc…
FULLTEXT: parallel database design randomized randomized -
Effect of Botulinum Toxin Injection Intervals on the Irreversibility of Targeted Muscle Paralysis: An Electromyographic Study.
[BACKGROUND] Botulinum neurotoxin A (BoNT-A) is widely used clinically, yet its temporary effects require repeated injections that increase cost and inconvenience. Claims that repeated BoNT-A use alters efficacy lack rigorous evaluation. Un…
FULLTEXT: parallel database design randomized randomized -
Refining the SPLF Graft: Innovations in Revision Rhinoplasty.
Reconstructing the dorsum in revision rhinoplasty remains a complex challenge. Traditional methods such as solid rib grafts and diced cartilage fascia (DCF) grafts present significant limitations, including warping, displacement, and insuff…
FULLTEXT: parallel database design randomized randomized -
Piezoelectric Versus Conventional Rhinoplasty: A GRADE-assessed Systematic Review and Meta-analysis of Randomized Controlled Trials.
Piezoelectric osteotomy may reduce postoperative morbidity after rhinoplasty, but time-based effects remain uncertain. We aimed to understand the time-based effectiveness and safety of piezoelectric osteotomy versus conventional method. We …
FULLTEXT: parallel database design randomized randomized -
The Efficacy Study of Facial Biomechanical A-Type Botox Injection in Reshaping the Jawline.
[BACKGROUND] Aging-related changes of the mandibular margin are common, and with increasing aesthetic awareness, the demand for non-surgical jawline rejuvenation is growing. [OBJECTIVES] To compare the efficacy and safety of a facial biome…
FULLTEXT: parallel database design randomized randomized -
A systematic review of clinical evidence on the efficacy and safety of conditioned media, platelet-rich fibrin, stromal vascular fraction, extracellular vesicles, and stem cells in androgenetic alopecia.
[AIMS AND OBJECTIVES] Androgenetic alopecia (AGA) is a common progressive hair loss disorder caused by follicular miniaturization and shortened anagen phases. Conventional treatments mainly target androgen pathways but often yield unsatisfa…
FULLTEXT: parallel database design randomized randomized -
Simulation-driven experiments resolve throttle pedal vibration issues.
This study investigates the resolution of accelerator pedal vibration issues during horn activation in vehicle tuning through finite element analysis combined with real-world test data. For certain facelift models experiencing NVH challenge…
FULLTEXT: parallel database design randomized randomized -
Perioperative Opioid Use and Risk of Persistent Use After Common Otolaryngologic Procedures.
[OBJECTIVE] The objective of this study was to evaluate the incidence of perioperative opioid prescription and the development of new persistent opioid usage in patients prescribed perioperative opioids for common otolaryngological procedur…
FULLTEXT: parallel database design randomized randomized -
Comparison of Polydioxanone and Polypropylene Sutures in Columellar Incision Closure: A Prospective Randomized Clinical Trial.
[BACKGROUND] Columellar scarring remains an important aesthetic concern in open septorhinoplasty, and while multiple studies have compared absorbable and non-absorbable sutures, the specific effects of slowly absorbable polydioxanone (PDS) …
FULLTEXT: parallel database design randomized randomized -
Mapping the Mandibular Lingual Foramina for Safer Chin Surgery: CT Morphometry and Predictive Modeling.
[BACKGROUND] Submental hematoma after genioplasty is rare but can be life-threatening, and current imaging data give limited patient-specific guidance for chin osteotomy design. [METHODS] We combined targeted cadaveric dissection of two pe…
FULLTEXT: parallel database design randomized randomized -
Streamlined Facial Rejuvenation: A Randomized Split-Face Trial of Premixed Intradermal Botulinum Toxin Type A and Hyaluronic Acid Biorevitalization.
TL;DRPremixed intradermal BoNT-A with NCTF 135HA achieved superior wrinkle reduction, enhanced skin quality, and greater patient satisfaction than BoNT-A alone, with minimal downtime and an excellent safety profile.
FULLTEXT: parallel database design randomized randomized