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[BACKGROUND] Pelvic lymph node dissection (PLND) remains controversial in the management of prostate cancer. Although it provides the most accurate pathological staging, its therapeutic value beyond staging has long been debated due to conf…

Prostate specific membrane antigen (PSMA)-positive exosomes hold significant potential for the diagnosis and risk assessment of prostate cancer. However, accurate detection is severely hindered by their low abundance in blood and interferen…

[BACKGROUND AND PURPOSE] In patients with biochemical recurrence (BCR) after radical prostatectomy (RP), prostate-specific membrane antigen (PSMA) PET/CT can detect early pelvic lymph node metastases, yet optimal management of these recurre…

TL;DRWhile mpMRI remains the preferred imaging modality for post-RP local recurrence surveillance, the integration of PSMA PET/CT may lead to improved specificity and inter-rater reliability, however, radiologists must unders…

TL;DRA novel, fully water-soluble small-molecule drug conjugate (SMDC), SN38-SS-3PEG24-3PSMA (SPP), designed for enhanced prostate cancer targeting and tumor-selective drug release, highlights SPP as a promising therapeutic c…

TL;DR18F-rhPSMA-7.3-PET/MRI can detect occult higher risk disease in men who are otherwise candidates for AS or FT and prompted major changes in management and increased confidence in the final treatment strategy.

[OBJECTIVE] To evaluate the potential of the signature index (S-index) and the shifted apparent diffusion coefficient (sADC), both markers of non-Gaussian diffusion, for the diagnosis of prostate cancer. [METHODS] This retrospective study …

TL;DRThe modified CEUS LI-RADS TRA emphasizing intralesional washout in LR-TR viable significantly improved specificity without compromising sensitivity and performed well in detecting LTP in ablated HCC.

High mammographic density is a well-known risk factor for breast cancer and reduces the sensitivity of mammography-based screening. While automated machine and deep learning-based methods provide more consistent and precise measurements com…

Metastatic castration‑resistant prostate cancer (mCRPC) remains a lethal disease due to universal resistance to androgen‑receptor pathway inhibitors (ARPI). Tumor progression is orchestrated by a spectrum of androgen‑receptor‑independent dr…

[CONTEXT] Ultrasound risk categories (thyroid imaging, reporting, and data systems, TI-RADS), fine-needle aspiration cytology (Bethesda), and molecular classifiers guide thyroid nodule management. However, these tools may perform differentl…

TL;DRKimura disease may cause false-positive results when using PSMA PET in the staging of prostate cancer, and this case indicates that KD may cause false-positive results when using PSMA PET in the staging of prostate cance…

TL;DRThe yield of fusion prostate biopsies at this institution is high and the positive predictive value (PPV) of magnetic resonance imaging–transrectal ultrasound (MRI-TRUS) machine fusion prostate biopsies, and to identify …

TL;DRThree assigned radiologists with different experience levels achieved generally poor inter‑reader agreement using the PI-RADS version 2.1 guideline, and varying expertise did not significantly influence PI-RADS 3 evaluat…

TL;DRA case of liver amoebic abscesses interpreted as necrotic hepatic metastases on ultrasonography showing PSMA expression in periphery of the early hepatic amoebic lesions is highlighted.

[PURPOSE] This investigation focused on developing a predictive clinical tool that combines biparametric MRI-derived PI-RADS v2.1 assessments with patient-specific biomarkers. The model was designed to optimize prostate cancer detection rel…

TL;DRThis retrospective study demonstrates successful implementation of microUS-guided biopsy, with similar rates of identification of csPCa compared to historical data using mpMRI-US fusion, supporting the combined approach …

TL;DRQuantitative SyMRI provides reproducible, contrast-free biomarkers that significantly enhance detection of peripheral zone prostate cancer beyond PI-RADS v2.1, and should be interpreted as exploratory and validated in la…

TL;DRA prostate MRI dataset from a screening population with histological confirmation was curated and evaluated with AI, and the neural network trained and tested on this data produced lower specificities than the radiologis…