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[OBJECTIVE] To evaluate the potential of the signature index (S-index) and the shifted apparent diffusion coefficient (sADC), both markers of non-Gaussian diffusion, for the diagnosis of prostate cancer. [METHODS] This retrospective study …

TL;DRThe modified CEUS LI-RADS TRA emphasizing intralesional washout in LR-TR viable significantly improved specificity without compromising sensitivity and performed well in detecting LTP in ablated HCC.

Fibroblast activation protein (FAP), a transmembrane serine protease overexpressed in tumor stroma, has emerged as a dual-purpose biomarker for cancer theranostics. Although FAP-targeting molecular imaging enables precise tumor visualizatio…

High mammographic density is a well-known risk factor for breast cancer and reduces the sensitivity of mammography-based screening. While automated machine and deep learning-based methods provide more consistent and precise measurements com…

TL;DRStromal FAP+ fibroblasts are unveiled as central regulators of macrophage-dependent immunosuppression via WNT2 signaling, proposing a novel therapeutic target to reprogram the TME in OSCC.

TL;DRThis review summarizes current progress in FAP-targeted radiopharmaceuticals and outlines strategies to enhance their therapeutic applicability through different strategies that lead to prolonged tumor retention.

Fibroblast activation protein (FAP) has emerged as a promising molecular target for theranostic strategies. Here is a case of a 37-year-old woman with poorly differentiated pancreatic adenocarcinoma with lymph node metastasis who received 1…

[CONTEXT] Ultrasound risk categories (thyroid imaging, reporting, and data systems, TI-RADS), fine-needle aspiration cytology (Bethesda), and molecular classifiers guide thyroid nodule management. However, these tools may perform differentl…

TL;DRThe yield of fusion prostate biopsies at this institution is high and the positive predictive value (PPV) of magnetic resonance imaging–transrectal ultrasound (MRI-TRUS) machine fusion prostate biopsies, and to identify …

TL;DRThree assigned radiologists with different experience levels achieved generally poor inter‑reader agreement using the PI-RADS version 2.1 guideline, and varying expertise did not significantly influence PI-RADS 3 evaluat…

[PURPOSE] This investigation focused on developing a predictive clinical tool that combines biparametric MRI-derived PI-RADS v2.1 assessments with patient-specific biomarkers. The model was designed to optimize prostate cancer detection rel…

TL;DRThis retrospective study demonstrates successful implementation of microUS-guided biopsy, with similar rates of identification of csPCa compared to historical data using mpMRI-US fusion, supporting the combined approach …

TL;DRQuantitative SyMRI provides reproducible, contrast-free biomarkers that significantly enhance detection of peripheral zone prostate cancer beyond PI-RADS v2.1, and should be interpreted as exploratory and validated in la…

TL;DRA prostate MRI dataset from a screening population with histological confirmation was curated and evaluated with AI, and the neural network trained and tested on this data produced lower specificities than the radiologis…

TL;DRWhether GPS adds predictive value beyond established clinical variables for adverse pathology at radical prostatectomy in active surveillance‐eligible patients in active surveillance‐eligible patients is assessed.

TL;DRResearch proposes that the loss of the Y chromosome (LOY) may affect the occurrence and development of prostate cancer, aiming to assess its potential as a diagnostic biomarker to improve the accuracy of prostate cancer …

TL;DRIt is evaluated whether combining pre‐operative clinical indicators and ¹⁸F‐PSMA‐1007 PET/CT could non‐invasively stratify HRPCa risk.

TL;DRThis study aimed to reassess the diagnostic value of DRE in the context of contemporary imaging tools, particularly mpMRI and PSMA PET/CT.

[PURPOSE] While the clinical value of magnetic resonance imaging (MRI)-ultrasound fusion-targeted prostate biopsy (TB) for index lesions (ILs) has been established, the utility of TB for non-index lesions (nILs) remains unclear. We evaluate…

[PURPOSE] Prostate-specific membrane antigen (PSMA) positron emission tomography and multiparametric magnetic resonance imaging (mpMRI) are used to contour the dominant intraprostatic lesion (DIL) when incorporating a microboost. However, i…