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Endodontic implications of hypercementosis: A systematic review of anatomical challenges and therapeutic strategies.
TL;DRA stepwise approach, ranging from clinical monitoring in asymptomatic cases to surgical interventions is recommended, and the integration of advanced imaging technologies and individualized treatment planning is essentia…
FULLTEXT: Computer Security -
Artificial intelligence in biomaterials for oral oncology.
Oral cancer and oral potentially malignant disorders (OPMDs) remain a significant challenge in diagnosis and therapy, primarily due to inherent limitations in early detection, targeted treatment, and postoperative rehabilitation. Convention…
FULLTEXT: Computer Security -
Decoding the impact of nsSNP variants on BCL6 function through integrated computational analysis.
TL;DRIt could be concluded that selected nsSNPs could lead to impaired BCL6 transcriptional repressive function due to loss of stability and binding affinity towards its corepressors.
FULLTEXT: Computer Security -
PIBAdb: a public cohort of multimodal colonoscopy videos and images including polyps with histological information.
TL;DRPIBAdb is one of the largest and most complete multimodal public datasets for colorectal polyp research and is characterized by its rich per-polyp metadata, inclusion of NBI and WL images, and non-polyp images at multipl…
FULLTEXT: Computer Security -
Image registration improves inter-reader agreement of objective response in CT assessment of pancreas adenocarcinoma.
TL;DRSubstantial measurement variability exists in CT assessment of PDAC tumor response during NAT, and longitudinal image registration improves reproducibility and diminishes experience gap in radiologist assessments of obje…
FULLTEXT: Computer Security -
Harnessing Artificial Intelligence for the Management of Patients With GI Cancers.
Artificial intelligence (AI) has the potential of reshaping GI oncology by enabling more nuanced interpretation of complex clinical, imaging, and molecular data, while supporting more timely and patient-centered decisions. This article synt…
FULLTEXT: Computer Security -
Targeting conserved domains of hypoxia-inducible factors for cancer therapy.
Hypoxia-inducible factors 1 and 2 (HIF-1/2) function as master regulators of cancer progression by regulating angiogenesis, cancer stem cell specification, epithelial-mesenchymal transition, immune evasion, tissue invasion, and metastasis. …
FULLTEXT: Computer Security -
Vincristine induces sperm malformation and motility dysfunction in mice by downregulating Tssk4 and Ccdc159.
TL;DRIt is established that VCR induces considerable reproductive toxicity, predominantly mediated through the suppression of Tssk4 and Ccdc159, thereby challenging its conventional low-risk categorization and providing a mec…
FULLTEXT: Computer Security -
Effect of Marital Status on Years of Life Lost From Metastatic Prostate Cancer According to Race/Ethnicity.
[INTRODUCTION] It is unknown whether marital status affects years of life lost (YLL) in metastatic prostate cancer (mPCa) according to race/ethnicity. [METHODS] Within the SEER database (2004-2021), unmarried and married mPCa patients aged…
FULLTEXT: Computer Security -
Global trends in artificial intelligence applications for gastric cancer prediction, treatment, and management: a topic modeling and bibliometric analysis.
TL;DRThe findings suggested that policymakers should prioritize targeted funding and equitable AI adoption in LMICs to reduce disparities and strategic efforts should be directed toward improving the quality of life for GC pa…
FULLTEXT: Computer Security -
H-DCA Net: Hierarchical dual-branch coordinate attention framework for multi-scale gastric histopathology diagnosis.
TL;DRThe proposed Hierarchical Dual-Branch Coordinate Attention Network serves as a high-precision foundation for an efficient, reliable, and interpretable auxiliary tool, offering robust support for automated gastric cancer …
FULLTEXT: Computer Security -
Artificial Intelligence and Its Role in Endoscopic Adenoma and Cancer Detection.
Colorectal cancer incidence and mortality have declined over time, due in part to high-quality screening and surveillance colonoscopy. Nevertheless, postcolonoscopy colorectal cancer (PCCRC) occurs in up to 7% of cases and is inversely rela…
FULLTEXT: Computer Security -
Artificial Intelligence for the Treatment and Management of Colorectal Liver Metastases.
Colorectal cancer (CRC) is the third most commonly diagnosed malignancy worldwide. Prognosis is significantly worsened in patients with colorectal liver metastases (CRLM), whose management requires a multidisciplinary approach encompassing …
FULLTEXT: Computer Security -
The Role of Perioperative Artificial Intelligence in Colon and Rectal Surgery.
Artificial intelligence (AI) is rapidly transforming surgical practice with growing applications in colon and rectal surgery. This review explores perioperative AI tools that assist with operative planning, intraoperative guidance, and outc…
FULLTEXT: Computer Security -
Predictive performance of image processing techniques in the diagnosis of bone metastasis: A meta-analysis of a confusion matrix.
Bone metastasis, a common cause of disability, markedly affects prognosis and life expectancy, and is usually diagnosed through radiographic imaging. An early and accurate diagnosis of bone metastasis is critical in order to optimize therap…
FULLTEXT: Computer Security -
Multimodal sparse fusion transformer network with spatio-temporal decoupling for breast tumor classification.
TL;DRA novel Multimodal Sparse Fusion Transformer Network (MSFT-Net), which achieves superior performance in multimodal breast tumor classification compared to state-of-the-art methods, providing fast and reliable support for…
FULLTEXT: Computer Security -
Atypical femoral fracture with early PET/CT changes from denosumab for metastatic breast cancer and transition from denosumab to zoledronic acid.
TL;DRA case of bilateral AFFs that was treated surgically in a middle-aged woman receiving oncologic doses of denosumab for treatment of metastatic breast cancer for seven years is described and the potential for earlier oppo…
FULLTEXT: Computer Security -
Channel-wise joint disentanglement representation learning for B-mode and super-resolution ultrasound based CAD of breast cancer.
TL;DRA novel dual-branch network with a Channel-Wise Joint Disentanglement Representation Learning (CW-JDRL) method is proposed for the multimodal ultrasound-based CAD of breast cancer, where one branch processes BUS and the …
FULLTEXT: Computer Security -
Screening for Lung Cancer.
Lung cancer screening with low-dose computed tomography (CT) reduces mortality but requires integrated, system-based implementation. Review of evolving screening strategies highlighting risk-prediction models, imaging advances, and Lung CT …
FULLTEXT: Computer Security -
Reducing false positives in breast cancer screening with computer-aided detection.
FULLTEXT: Computer Security