Deciphering genetic regulation at single-cell resolution in gastric cancer.
Understanding cell-type-specific genetic regulation in gastric cancer is essential for uncovering disease susceptibility.
APA
Chen C, Han L (2025). Deciphering genetic regulation at single-cell resolution in gastric cancer.. Cell genomics, 5(4), 100846. https://doi.org/10.1016/j.xgen.2025.100846
MLA
Chen C, et al.. "Deciphering genetic regulation at single-cell resolution in gastric cancer.." Cell genomics, vol. 5, no. 4, 2025, pp. 100846.
PMID
40209679
Abstract
Understanding cell-type-specific genetic regulation in gastric cancer is essential for uncovering disease susceptibility. By performing single-cell eQTL mapping in gastric tissues, Bian et al. identified previously uncharacterized regulatory genetic mechanisms, risk genes, and co-localization signals associated with gastric cancer susceptibility, providing insights into its pathogenesis and potential therapeutic approaches.
MeSH Terms
Stomach Neoplasms; Humans; Single-Cell Analysis; Gene Expression Regulation, Neoplastic; Genetic Predisposition to Disease; Quantitative Trait Loci
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