논문 목록
6건-
Immune checkpoint inhibitor-based first-line therapies for advanced or unresectable hepatocellular carcinoma: a network meta-analysis and cost-effectiveness analysis.
[BACKGROUND] Immune checkpoint inhibitors (ICIs) have transformed the treatment landscape of advanced or unresectable hepatocellular carcinoma (HCC). However, the comparative clinical efficacy and cost-effectiveness of various ICI-based com…
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The progress of biomarkers detection to lung cancer.
[BACKGROUND] Lung cancer is a leading cause of cancer mortality, largely due to late-stage diagnosis. Biomarker detection is critical for early screening, molecular subtyping, and personalized therapy. This review summarizes the categories …
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Integrated nomogram for predicting intracranial progression-free survival with EGFR-TKI combined with cranial radiotherapy: a multicenter study.
[OBJECTIVE] Development and validation of a nomogram integrating clinical characteristics, Lung Molecular Graded Prognostic Assessment (Lung-molGPA) score, and MRI-based radiomics to predict intracranial progression-free survival (iPFS) in …
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Unraveling pancreatic ductal adenocarcinoma at single-cell resolution with spatial insights: From mechanisms to clinical translation.
Pancreatic ductal adenocarcinoma (PDAC) remains one of the most lethal cancers, characterized by pronounced cellular heterogeneity, a dense desmoplastic stroma, and a highly immunosuppressive tumor microenvironment (TME). Recent advances in…
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A narrative review of the early diagnosis and treatment of idiopathic pulmonary fibrosis with lung cancer.
[BACKGROUND AND OBJECTIVE] Idiopathic pulmonary fibrosis (IPF), a chronic progressive interstitial lung disease of unknown etiology, is characterized by alveolar architecture destruction and progressive pulmonary parenchymal scarring, with …
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KNTC1 functions as a potential biomarker and oncogene regulating proliferation, migration and apoptosis in gastric cancer.
[BACKGROUND] As one of the most prevalent cancers, gastric cancer (GC) exhibits a remarkably high morbidity and mortality rate. To date, effective diagnostic and prognostic markers and therapeutic targets for GC are still lacking. Kinetocho…