Wang H ⚠ 동명이인 가능성

[UNLABELLED] Immunotherapy often fails in solid tumors due to an immunosuppressive tumor microenvironment, driven in part by dysfunctional dendritic cells (DC) impairing antigen presentation and suppressive neutrophils. Recent studies revea…

[OBJECTIVE] This prospective study aimed to develop and validate integrated nomograms that combine preoperative radiomic features from dual-layer spectral detector CT (DLCT) with key postoperative pathological information for the prediction…

[BACKGROUND] Atypical teratoid/rhabdoid tumors (AT/RT) are rare, highly aggressive pediatric central nervous system (CNS) malignancies. AT/RT of the lateral ventricle is an exceptionally rare subgroup, with only 11 reported cases. inactiva…

Mycosis fungoides is characterized by widespread skin patches that may progress to plaques and tumors, necessitating precise tumor burden assessment for staging and treatment guidance. However, existing methods, including the widely accepte…

[BACKGROUND AND OBJECTIVES] Bacterial colonization, particularly by Staphylococcus aureus (SA), is prevalent on the skin of patients with primary cutaneous T-cell lymphoma (CTCL). This study aimed to investigate risk factors for cutaneous b…

High-altitude retinopathy (HAR) arises under acute hypobaric hypoxia (AHH), yet the temporal coupling of oxidative stress, apoptosis and cytokine signaling in the retina remains unclear. We exposed healthy male C57BL/6 mice to a hypobaric c…

[BACKGROUND] Progressive multifocal leukoencephalopathy (PML) is a rare, often fatal demyelinating disease caused by JC virus reactivation in immunocompromised patients. With the increasing use of immunosuppressants and biologics, PML repor…

[PURPOSE] To evaluate the role of chest CT radiomics in classifying mediastinal lymphadenopathy caused by hematologic malignancies and abdominopelvic solid cancers. [MATERIALS AND METHODS] A total of 231 patients with mediastinal lymphaden…

Phosphoglycerate kinase 1 (PGK1) is traditionally recognized for its pivotal role in glycolysis. Our findings reveal that PGK1 also functions as a protein kinase phosphorylating valosin-containing protein (VCP) at S746, which subsequently r…

[BACKGROUND] Patients with Sjögren's syndrome (SS) are at significantly increased risk of developing non-Hodgkin lymphoma (NHL). However, effective biomarkers to identify the subgroup of SS patients who will progress to lymphoma are current…

To evaluate the efficacy and safety of the RMT regimen as first-line induction therapy for primary central nervous system diffuse large B-cell lymphoma (PCNS-DLBCL), we retrospectively analyzed 36 patients treated with 4-6 cycles of RMT. Af…

[BACKGROUND] Percutaneous biopsy is a commonly used method for the early pathological diagnosis of pancreatic cancer. As an important imaging modality, contrast-enhanced ultrasound (CEUS) improves the characterization of pancreatic lesions …

[BACKGROUND] Collagen type XI alpha 1 (COL11A1) is overexpressed in pancreatic cancer and is often associated with poor survival, chemoresistance, and tumor recurrence. However, the role of COL11A1 in pancreatic cancer remains poorly unders…

Pancreatic ductal adenocarcinoma (PDAC) remains highly lethal due to intrinsic and acquired chemotherapy resistance, particularly after neoadjuvant therapy (NAT). To uncover therapy-induced vulnerabilities, we established matched patient-de…

[BACKGROUND] To explore the relationship between anti-thyroglobulin antibody (TgAb) trajectories and recurrence risk in papillary thyroid cancer (PTC) patients. [METHODS] This multiple-center, retrospective cohort included 4161 patients wh…

[BACKGROUND] Gastric intestinal metaplasia (GIM) is a precancerous lesion that elevates gastric cancer risk. Our prior single-cell RNA sequencing (scRNA-seq) analysis implied aberrant lipid metabolism in GIM. We also established a Ddit4-def…

[BACKGROUND] T2-T4 gastric cancer often has distant metastasis.The aim of this study is to establish and validate a prediction model for distant metastasis of T2-T4 gastric cancer using machine learning algorithms. [METHODS] We developed n…

[BACKGROUND & OBJECTIVE] Endoscopic Submucosal Dissection (ESD) effectively treats early gastric cancer, but postoperative complications limit its clinical use. Therefore, this study examines how esophageal mucosal wound protective gels imp…

The direct use of chemotherapeutic agents in gastric cancer treatment can result in systemic adverse effects and inadequate therapeutic efficacy. The superior features of nanoparticles provide them with potent tools for enhancing the target…

[BACKGROUND] Robotic-assisted gastrectomy (RG) has emerged as a promising surgical option for gastric cancer, offering potential clinical benefits over open and laparoscopic approaches. However, disparities in its use remain underexplored. …

A retrospective analysis was conducted on the positive rate of HER2 in gastric cancer in the Chinese high-incidence area of Wuwei from 2015 to 2024. The pathological characteristics of HER2-positive gastric cancer were explored to provide a…

Arenobufagin (ARBU), a steroid compound extracted from the venom of Bufo gargarizans, exhibits multi-target pharmacological activities, yet its role in regulating ferroptosis in gastric cancer stem cells (GCSCs) remains unclear. This study …

The existing TNM staging system provides insufficient prognostic information in gastric cancer (GC) patients. This study aims to establish a pathomics signature of GC (PS) that uses deep learning (DL) to directly analyze H&E slides for pred…

This study investigated the synergistic effect of l-arginine [inducible nitric oxide synthase (iNOS) substrate] combined with 5-fluorouracil (5-FU, iNOS inducer) on epithelial-mesenchymal transition (EMT) in hepatocellular carcinoma (HCC).,…

Liver cancer, primary hepatocellular carcinoma (HCC), posing a significant threat to human health due to its high prevalence and limited treatment options. As a first-line chemotherapeutic agent for HCC, 5-fluorouracil (5-FU) has demonstrat…

[OBJECTIVE] The aim of this study is to elucidate the effects and mechanism of narirutin (NR) in colorectal cancer (CRC). [METHODS] Flow cytometry, xenograft model, cell counting kit-8, colony formation, wound healing, and Transwell assays…