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Predictors of Outcome Clusters in Patients With Unruptured Intracranial Aneurysms Treated With Microsurgery: An Unsupervised Machine Learning Analysis.
[BACKGROUND AND OBJECTIVES] Identifying surgical candidates who are prone to poor outcomes is crucial for adapting treatment and ensuring optimal outcomes. Our aim was to use unsupervised machine learning to reveal patient outcome subgroups…
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Outcomes of Microsurgical Treatment for Unruptured Intracranial Aneurysms: A 7-Year Institutional Review.
[BACKGROUND AND OBJECTIVES] The optimal management of unruptured intracranial aneurysms (UIAs) remains controversial. Options include observation, endovascular treatment, microsurgical intervention, or a combination. However, clear outcome …
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A 7-Year Experience in Microsurgical Treatment of Unruptured Intracranial Aneurysms in Older Patients.
[BACKGROUND AND OBJECTIVES] Controversy exists regarding whether to treat unruptured intracranial aneurysms (UIAs) in older patients. This study analyzes modern outcomes among older patients who underwent microsurgical treatment for UIA. […
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Microsurgical versus endovascular treatment of ethmoidal dural arteriovenous fistulas: systematic review and meta-analysis with a single-center case series.
[OBJECTIVE] Ethmoidal dural arteriovenous fistulas (DAVFs) are often associated with cortical venous drainage (CVD) and a higher incidence of hemorrhage compared with DAVFs in other locations. They may be treated with open surgical disconne…
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Mortality After Microsurgical Treatment of Unruptured Intracranial Aneurysms in the Modern Era.
[BACKGROUND] The incidence of mortality after treatment of unruptured intracranial aneurysms (UIAs) has been described historically. However, many advances in microsurgical treatment have since emerged, and most available data are outdated.…
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Gene expression signatures of breast cancer stem and progenitor cells do not exhibit features of Warburg metabolism.
[INTRODUCTION] Cancers are believed to adapt to continual changes in glucose and oxygen availability by relying almost exclusively on glycolytic metabolism for energy (i.e. the Warburg effect). The process by which breast cancers sustain gr…