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High-Resolution Vessel Wall Imaging for Treatment Sequencing of Multiple Aneurysms in Subarachnoid Hemorrhage.
[OBJECTIVES] Approximately 30% of patients with subarachnoid hemorrhage (SAH) present with multiple aneurysms. Identifying the ruptured aneurysm is often difficult, and not all lesions may be accessible through a single craniotomy. Magnetic…
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Predictors of Outcome Clusters in Patients With Unruptured Intracranial Aneurysms Treated With Microsurgery: An Unsupervised Machine Learning Analysis.
[BACKGROUND AND OBJECTIVES] Identifying surgical candidates who are prone to poor outcomes is crucial for adapting treatment and ensuring optimal outcomes. Our aim was to use unsupervised machine learning to reveal patient outcome subgroups…
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Outcomes of Microsurgical Treatment for Unruptured Intracranial Aneurysms: A 7-Year Institutional Review.
[BACKGROUND AND OBJECTIVES] The optimal management of unruptured intracranial aneurysms (UIAs) remains controversial. Options include observation, endovascular treatment, microsurgical intervention, or a combination. However, clear outcome …
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Aneurysm formation and postcoiling recurrence in HIV-associated vasculopathy: illustrative case.
[BACKGROUND] Human immunodeficiency virus (HIV) infection is linked with an uncommon vasculopathy syndrome, increasing the susceptibility of infected individuals to develop aneurysms across systemic vasculature, notably in the cerebral vasc…
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Management and outcomes for thoracic anterior spinal artery aneurysms: illustrative case.
[BACKGROUND] Anterior spinal artery (ASA) aneurysms are uncommon and difficult to diagnose due to their variable presentation and limited visibility with traditional imaging. They often present with severe back pain from rupture and spinal …
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Comparative meta-analysis of microsurgery versus endovascular therapy and bypass versus nonbypass techniques for blister-like aneurysms: enigmas of the supraclinoid internal carotid artery.
[OBJECTIVE] Blister aneurysms of the internal carotid artery (ICA) have high associated mortality rates and are challenging due to their friable wall and poorly defined neck. Microsurgical and endovascular treatment options have been sugges…
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Efficacy and safety of preoperative embolization in surgical treatment of brain arteriovenous malformations: a multicentre study with propensity score matching.
[BACKGROUND] Brain arteriovenous malformations (AVMs) are abnormal connections between feeding arteries and draining veins, associated with significant risks of haemorrhage, seizures and other neurological deficits. Preoperative embolizatio…
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Safety and efficacy of preoperative embolization in the treatment of brain arteriovenous malformations with perinidal aneurysms and single draining vein: a multicenter study with propensity score-weighting.
[BACKGROUND AND OBJECTIVES] Arteriovenous malformations (AVMs) with perinidal aneurysms and single draining vein are associated with an elevated risk of rupture and increased procedural complexity. The role of preoperative embolization in t…
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Microsurgical management of 883 previously coiled intracranial aneurysms: a systematic review, meta-analysis, and meta-regression of its effectiveness and safety.
[OBJECTIVE] With the increasing number of intracranial aneurysms (IAs) treated by endovascular coiling, more residual and recurrent IAs are being encountered. This study aimed to evaluate the effectiveness and safety of the microsurgical ma…
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Extended Retrosigmoid Craniotomy for Resection of a Cochlear Schwannoma.
Cochlear schwannomas are a rare subset of schwannomas arising from the cochlear nerve within the cochlea or internal auditory canal. These tumors can present with posterior displacement of the facial nerve, making facial nerve preservation …
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A 7-Year Experience in Microsurgical Treatment of Unruptured Intracranial Aneurysms in Older Patients.
[BACKGROUND AND OBJECTIVES] Controversy exists regarding whether to treat unruptured intracranial aneurysms (UIAs) in older patients. This study analyzes modern outcomes among older patients who underwent microsurgical treatment for UIA. […
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Contemporary adverse event profile of microsurgery for intracranial unruptured aneurysms in high-volume microsurgical centers: the international PRAEMIUM study.
[OBJECTIVE] Objective values on procedural risk are essential to facilitate informed consent and optimize clinical decision-making in patients with unruptured intracranial aneurysms (UIAs). While robust heuristics, such as the PHASES (popul…
- Introduction. Microsurgery of intracranial aneurysms: why it should continue.
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Microsurgery and endovascular therapy serve instrumental roles in multimodal management of giant cerebral aneurysms: a systematic review.
[INTRODUCTION] Giant intracranial aneurysms are rare vascular lesions consisting of cerebral aneurysms measuring ≥25 mm in diameter. Their formation is the result of multiple factors including their association with a unique genomic landsca…
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Risk Models for Adverse Events in Microsurgery for Intracranial Unruptured Aneurysms.
[BACKGROUND AND OBJECTIVES] Preventive treatment of unruptured intracranial aneurysms (UIAs) requires assessment of treatment risks vs expected benefit. Although established scores exist to estimate rupture and growth risk, currently, no ex…
- Surgical treatment of giant intracranial aneurysms: A systematic review and single arm Meta-Analysis.
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The biportal transorbital approach: quantitative comparison of the anterior subfrontal craniotomy, bilateral transorbital endoscopic, and microscopic approaches.
[OBJECTIVE] The aim of this study was to assess the surgical use and applicability of a biportal bitransorbital approach. Single-portal transorbital and combined transorbital transnasal approaches have been used in clinical practice, but no…
- Extended Retrosigmoid Craniotomy for Resection of an Abducens Schwannoma.
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Latex vascular injection as method for enhanced neurosurgical training and skills.
[BACKGROUND] Tridimensional medical knowledge of human anatomy is a key step in the undergraduate and postgraduate medical education, especially in surgical fields. Training simulation before real surgical procedures is necessary to develop…
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Enhancing the quality of evidence, comparability, and reproducibility in brain arteriovenous malformations treated with open surgery research: a systematic review and proposal of a reporting guideline for surgical and clinical outcomes.
Brain Arteriovenous Malformations (bAVMs) are rare but high-risk developmental anomalies of the vascular system. Microsurgery through craniotomy is believed to be the mainstay standard treatment for many grades of bAVMs. However, a signific…
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Most Promising Approaches to Improve Brain AVM Management: ARISE I Consensus Recommendations.
Brain arteriovenous malformations (bAVMs) are complex, and rare arteriovenous shunts that present with a wide range of signs and symptoms, with intracerebral hemorrhage being the most severe. Despite prior societal position statements, ther…
- Clip Reconstruction of a Ruptured Thoracic Anterior Spinal Artery Aneurysm Utilizing a Costotransversectomy Approach: 2-Dimensional Operative Video.
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Minimally invasive keyhole craniotomies for microsurgical clipping of cerebral aneurysms: comparative meta-analysis of the mini-pterional and supraorbital keyhole approaches.
[OBJECTIVE] Axel Perneczky is responsible for conceptualizing the "keyhole" philosophy as a new paradigm of minimal invasiveness within cranial neurosurgery. Keyhole neurosurgery aims to limit approach-related traumatization and minimize br…
- Perspectives on Brain Arteriovenous Malformations From the Surgical Battlefield.
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Transorbital Microsurgery: An Anatomical Description of a Minimally Invasive Corridor to the Anterior Cranial Fossa and Paramedian Structures.
Transorbital neuroendoscopic surgery (TONES) has ignited interest in the transorbital access corridor, increasing its use for single and multi-portal skull base interventions. However, the crowding of a small corridor and two-dimensional v…
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Arteriovenous malformations in the cerebellopontine angle: assessment of the "backdoor resection" technique and microsurgical results in 38 patients.
[OBJECTIVE] Posterior fossa arteriovenous malformations (AVMs) represent 7% to 15% of all intracranial AVMs and are associated with an increased risk of hemorrhage, morbidity, and mortality compared with supratentorial AVMs, thus prompting …
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Microsurgical Obliteration of Craniocervical Junction Dural Arteriovenous Fistulas: Multicenter Experience.
[BACKGROUND] Dural arteriovenous fistulas (dAVFs) located at craniocervical junction are extremely rare (1%-2% of intracranial/spinal dAVFs). Their angio-architectural complexity renders endovascular embolization to be challenging given mul…
- In Reply: Cost Comparison of Microsurgery vs Endovascular Treatment for Ruptured Intracranial Aneurysms: A Propensity-Adjusted Analysis.
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Virtual neurosurgery anatomy laboratory: A collaborative and remote education experience in the metaverse.
[BACKGROUND] Advances in computer sciences, including novel 3-dimensional rendering techniques, have enabled the creation of cloud-based virtual reality (VR) interfaces, making real-time peer-to-peer interaction possible even from remote lo…
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Application of diffusion tensor-based tractography in treatment of brain arteriovenous malformations: a systematic review.
There is no systematic review investigating the utility of Diffusion tensor-based tractography findings for treating brain arteriovenous malformations (bAVMs). This systematic review aims to investigate the outcomes following bAVM treatment…