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High-Resolution Vessel Wall Imaging for Treatment Sequencing of Multiple Aneurysms in Subarachnoid Hemorrhage.
[OBJECTIVES] Approximately 30% of patients with subarachnoid hemorrhage (SAH) present with multiple aneurysms. Identifying the ruptured aneurysm is often difficult, and not all lesions may be accessible through a single craniotomy. Magnetic…
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Predictors of Outcome Clusters in Patients With Unruptured Intracranial Aneurysms Treated With Microsurgery: An Unsupervised Machine Learning Analysis.
[BACKGROUND AND OBJECTIVES] Identifying surgical candidates who are prone to poor outcomes is crucial for adapting treatment and ensuring optimal outcomes. Our aim was to use unsupervised machine learning to reveal patient outcome subgroups…
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Outcomes of Microsurgical Treatment for Unruptured Intracranial Aneurysms: A 7-Year Institutional Review.
[BACKGROUND AND OBJECTIVES] The optimal management of unruptured intracranial aneurysms (UIAs) remains controversial. Options include observation, endovascular treatment, microsurgical intervention, or a combination. However, clear outcome …
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Comparative meta-analysis of microsurgery versus endovascular therapy and bypass versus nonbypass techniques for blister-like aneurysms: enigmas of the supraclinoid internal carotid artery.
[OBJECTIVE] Blister aneurysms of the internal carotid artery (ICA) have high associated mortality rates and are challenging due to their friable wall and poorly defined neck. Microsurgical and endovascular treatment options have been sugges…
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A 7-Year Experience in Microsurgical Treatment of Unruptured Intracranial Aneurysms in Older Patients.
[BACKGROUND AND OBJECTIVES] Controversy exists regarding whether to treat unruptured intracranial aneurysms (UIAs) in older patients. This study analyzes modern outcomes among older patients who underwent microsurgical treatment for UIA. […
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Microsurgery and endovascular therapy serve instrumental roles in multimodal management of giant cerebral aneurysms: a systematic review.
[INTRODUCTION] Giant intracranial aneurysms are rare vascular lesions consisting of cerebral aneurysms measuring ≥25 mm in diameter. Their formation is the result of multiple factors including their association with a unique genomic landsca…
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Minimally invasive keyhole craniotomies for microsurgical clipping of cerebral aneurysms: comparative meta-analysis of the mini-pterional and supraorbital keyhole approaches.
[OBJECTIVE] Axel Perneczky is responsible for conceptualizing the "keyhole" philosophy as a new paradigm of minimal invasiveness within cranial neurosurgery. Keyhole neurosurgery aims to limit approach-related traumatization and minimize br…
- Perspectives on Brain Arteriovenous Malformations From the Surgical Battlefield.
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Arteriovenous malformations in the cerebellopontine angle: assessment of the "backdoor resection" technique and microsurgical results in 38 patients.
[OBJECTIVE] Posterior fossa arteriovenous malformations (AVMs) represent 7% to 15% of all intracranial AVMs and are associated with an increased risk of hemorrhage, morbidity, and mortality compared with supratentorial AVMs, thus prompting …
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Microsurgical Obliteration of Craniocervical Junction Dural Arteriovenous Fistulas: Multicenter Experience.
[BACKGROUND] Dural arteriovenous fistulas (dAVFs) located at craniocervical junction are extremely rare (1%-2% of intracranial/spinal dAVFs). Their angio-architectural complexity renders endovascular embolization to be challenging given mul…
- In Reply: Cost Comparison of Microsurgery vs Endovascular Treatment for Ruptured Intracranial Aneurysms: A Propensity-Adjusted Analysis.
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Transvenous Embolization of Dural Arteriovenous Fistulas Through the Galenic (Deep Venous) System: Multicenter Case Series and Meta-Analysis.
[BACKGROUND AND OBJECTIVES] Arteriovenous fistulas involving the deep venous system have often been treated with microsurgery or transarterial embolization. Increasing familiarity with transvenous navigation and improved endovascular access…
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Mortality After Microsurgical Treatment of Unruptured Intracranial Aneurysms in the Modern Era.
[BACKGROUND] The incidence of mortality after treatment of unruptured intracranial aneurysms (UIAs) has been described historically. However, many advances in microsurgical treatment have since emerged, and most available data are outdated.…
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Management of basilar fenestration aneurysms: a systematic review with an illustrative case report.
[BACKGROUND] Basilar artery (BA) fenestration aneurysm (BAFA) is a rare phenomenon commonly accompanying other aneurysms. Treatment is challenging, and few cases have been reported. This review investigated the management outcomes of BAFAs.…
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Microsurgical Treatment of Cerebral Aneurysms.
Despite advances in endovascular techniques, microsurgery continues to play an important role in the treatment of cerebral aneurysms. This article reviews the history of surgical treatment of intracranial aneurysms and the evolving role of …
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The Times They Are a-Changin': Increasing Complexity of Aneurysmal Subarachnoid Hemorrhages in Patients Treated from 2004 to 2018.
[BACKGROUND] Nationwide study results have suggested varying trends in the incidence of aneurysmal subarachnoid hemorrhage (aSAH) over time. Herein, trends over time for aSAH treated at a quaternary care center are compared with low-volume …
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Saccular aneurysms in the post-Barrow Ruptured Aneurysm Trial era.
[OBJECTIVE] The Barrow Ruptured Aneurysm Trial (BRAT) was a single-center trial that compared endovascular coiling to microsurgical clipping in patients treated for aneurysmal subarachnoid hemorrhage (aSAH). However, because patients in the…
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Vertebrobasilar dissecting aneurysms: microsurgical management in 42 patients.
[OBJECTIVE] Vertebrobasilar dissecting (VBD) aneurysms are rare, and patients with these aneurysms often present with thromboembolic infarcts or subarachnoid hemorrhage (SAH). The morphological nature of VBD aneurysms often precludes conven…
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Cost Comparison of Microsurgery vs Endovascular Treatment for Ruptured Intracranial Aneurysms: A Propensity-Adjusted Analysis.
[BACKGROUND] In specialized neurosurgical centers, open microsurgery is routinely performed for aneurysmal subarachnoid hemorrhage (aSAH). [OBJECTIVE] To compare the cost of endovascular vs microsurgical treatment for aSAH at a single quat…
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The Glossopharyngo-Cochlear Triangle-Part II: Case Series Highlighting the Clinical Application to High-Riding Posterior Inferior Cerebellar Artery Aneurysms Exposed Through the Extended Retrosigmoid Approach.
[BACKGROUND] Use of the far lateral transcondylar (FL) approach and vagoaccessory triangle is the standard exposure for clipping most posterior inferior cerebellar artery (PICA) aneurysms. However, a distal PICA origin or high-lying vertebr…
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Spetzler-Martin Grade III Arteriovenous Malformations: A Comparison of Modified and Supplemented Spetzler-Martin Grading Systems.
[BACKGROUND] The modified Spetzler-Martin (SM) grading system proposes that grade III arteriovenous malformation (AVM) subtypes are associated with variable microsurgical risks, with small AVMs (III-) having lower risk and medium/eloquent A…
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Dissecting Fusiform PICA Aneurysm Repair With Trapping and an Unconventional End-to-Side Reanastomosis: 2-Dimensional Operative Video.
Dissecting fusiform posterior inferior cerebellar artery (PICA) aneurysms are rare and challenging.1,2 One common treatment is occlusion of the aneurysm and parent artery via an endovascular approach without revascularization.3 Revasculariz…
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Treatment of octogenarians and nonagenarians with aneurysmal subarachnoid hemorrhage: a 17-year institutional analysis.
[BACKGROUND] Outcomes for octogenarians and nonagenarians after an aneurysmal subarachnoid hemorrhage (aSAH) are particularly ominous, with mortality rates well above 50%. The present analysis examines the neurologic outcomes of patients ≥ …
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Using the Lateral Pontine Safe Entry Zone for Resection of Deep-Seated Cavernous Malformations in the Lateral Pons: 2-Dimensional Operative Video.
The retrosigmoid approach is one of the main approaches used in the surgical management of pontine cavernous malformations. It definitely provides a lateral route to large central lesions but also makes possible resection of some ventral le…