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  • Transcriptomic and Proteomic Characterization of the Immune Response to Elective Spinal Reconstructive Surgery: Impact of Aging and Comparison with Traumatic Injury Response.
    Journal of the American College of Surgeons 2024 Bonaroti JW 🟢 PMC 🆕 신규 PMID: 38095316 ↗

    TL;DRAlthough both major surgery and polytrauma initiate immune and stress responses, substantial differences exist in timing and cellular profiles, suggesting major elective surgery is not a suitable surrogate for the polytr…

    Transcriptomic and Proteomic Characterization of the Immune Response to Elective Spinal Recons…

    키워드: Transcriptomic (제목)
  • Twenty Years of Macromastia Research: A Comprehensive Analysis of Diagnostic Standardization, Surgical Technique Optimization, and Exploration of Molecular Mechanisms.
    Aesthetic surgery journal 2026 Wu KJ 🆕 신규 PMID: 41612795 ↗ 기술보고

    TL;DRThis study synthesizes two decades of macromastia research, documents the transition toward quantitative standards, and nominates molecular pathways warranting further validation.

    …nd incomplete mechanistic understanding. We combined bibliometric analysis with transcriptomic profiling to map research evolution and identify candidate molecular pathways. …

    키워드: Transcriptomic (초록)
  • Transcriptomic and machine learning analyses identify hub genes of metabolism and host immune response that are associated with the progression of breast capsular contracture.
    Genes & diseases 2024 Mao Y 🟢 PMC 🆕 신규 PMID: 38292203 ↗

    TL;DRThe findings indicate that PRKAR2B is a novel diagnostic biomarker for breast capsular contracture and might also influence the grade and progression of capsular contracture.

    Transcriptomic and machine learning analyses identify hub genes of metabolism and host immune …

    키워드: Transcriptomic (제목)
  • Fuhu Lijie Tang treats rheumatoid arthritis through multitarget therapy from autoantigen formation to bone destruction.
    Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Yao Z 🆕 신규 PMID: 40706389 ↗

    TL;DRFHLJT exerts its therapeutic effects by simultaneously targeting multiple key pathological mechanisms of RA through 74 compounds which modulate processes such as citrullinated protein production, antigen presentation, TC…

    … measurement, inflammatory marker analysis, and histopathology. Synovial tissue transcriptomics identified differentially expressed genes, followed by validation through West…

    키워드: Transcriptomic (초록)
  • Exome and transcriptome analysis link calcium channel pathway aberrations to botulinum toxin A resistance in Hailey-Hailey disease.
    The British journal of dermatology 2025 Yuan Y 🆕 신규 PMID: 40317184 ↗

    TL;DRCombined transcriptomic analysis and IHC indicate the upregulation of ORAI1/SOCE pathway may potentially contribute to treatment resistance and serve as biomarkers for predicting patient responsiveness.

    … mutation in ATP2C1 in patients with HHD and their response to BoNTA treatment. Transcriptomic analysis and IHC of baseline skin lesions revealed an overactivated store-opera…

    키워드: Transcriptomic (초록)
  • Aralia saponin A isolated from Achyranthes bidentata Bl. ameliorates LPS/D-GalN induced acute liver injury via SPHK1/S1P/S1PR1 pathway in vivo and in vitro.
    International immunopharmacology 2023 Zeng M 📖 OA PDF 🆕 신규 PMID: 37699301 ↗

    … were determined to assess the oxidative stress damage and inflammatory injury. Transcriptomics and metabonomics analysis were employed to clarify the mechanisms. Additionall…

    키워드: Transcriptomic (초록)
  • Transcriptomic response of intertidal brittle star Ophiothrix exigua to seasonal variation.
    Marine genomics 2022 Fuad MTI 🆕 신규 PMID: 35580505 ↗

    Transcriptomic response of intertidal brittle star Ophiothrix exigua to seasonal variation.

    키워드: Transcriptomic (제목)
  • Profiling gene expression reveals insights into pulmonary response to aerosolized botulinum toxin type A exposure in mice.
    Journal of applied toxicology : JAT 2021 Su D 🆕 신규 PMID: 33529366 ↗

    …lized BoNT/A and described through histological examination and flow cytometry. Transcriptomic analysis revealed that genes related to acute inflammatory responses were upreg…

    키워드: Transcriptomic (초록)
  • In Vitro Bioactivity of a Recombinant Human Collagen Peptide in a Filler Biomimetic Skin Model.
    Journal of cosmetic dermatology 2025 He C 🟢 PMC 🆕 신규 PMID: 41384336 ↗

    …ration and differentiation, as well as dermal ECM deposition were investigated. Transcriptomic analysis further offered an in-depth view of molecular pathways underlying the …

    키워드: Transcriptomic (초록)
  • Impact of Hematoma on Capsular Contracture: A Comparative Study of Smooth and Textured Implants in a Miniature Pig Model.
    Aesthetic surgery journal 2024 Zhang X 🆕 신규 PMID: 38885307 ↗

    TL;DRHematomas increase the risk of capsular contracture, with smooth implants exacerbating this effect by enhancing pathways related to muscle development and contraction, and the importance of hematoma prevention and treatm…

    …s exhibited increased muscle content and biomechanical strength of the capsule. Transcriptomic analysis highlighted differential gene expression related to muscle development…

    키워드: Transcriptomic (초록)