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Potential of the signature index (S-index), a diffusion MRI Biomarker, to enhance diagnosis of clinically significant prostate cancer and decrease the rate of unnecessary biopsies.
[OBJECTIVE] To evaluate the potential of the signature index (S-index) and the shifted apparent diffusion coefficient (sADC), both markers of non-Gaussian diffusion, for the diagnosis of prostate cancer. [METHODS] This retrospective study …
FULLTEXT: LI-RADS -
Local Tumor Progression After Hepatocellular Carcinoma Ablation: CEUS LI-RADS Nonradiation TRA Version 2024 Versus a Modified Algorithm.
TL;DRThe modified CEUS LI-RADS TRA emphasizing intralesional washout in LR-TR viable significantly improved specificity without compromising sensitivity and performed well in detecting LTP in ablated HCC.
FULLTEXT: LI-RADS -
The DeepJoint Algorithm: An Innovative Approach for Studying the Longitudinal Evolution of Quantitative Mammographic Density and Its Association With Screen-Detected Breast Cancer Risk.
High mammographic density is a well-known risk factor for breast cancer and reduces the sensitivity of mammography-based screening. While automated machine and deep learning-based methods provide more consistent and precise measurements com…
FULLTEXT: LI-RADS -
Assessing the accuracy of thyroid nodule risk-stratification tools in Hispanic and non-Hispanic patients.
[CONTEXT] Ultrasound risk categories (thyroid imaging, reporting, and data systems, TI-RADS), fine-needle aspiration cytology (Bethesda), and molecular classifiers guide thyroid nodule management. However, these tools may perform differentl…
FULLTEXT: LI-RADS -
The Diagnostic Yield of MRI-Transrectal US Fusion Prostate Biopsy in Patients With Suspected Prostate Cancer.
TL;DRThe yield of fusion prostate biopsies at this institution is high and the positive predictive value (PPV) of magnetic resonance imaging–transrectal ultrasound (MRI-TRUS) machine fusion prostate biopsies, and to identify …
FULLTEXT: LI-RADS -
Evaluating the impact of reader experience on PI-RADS 3 of version 2.1 scoring concordance in multiparametric prostate MRI: a single-center analysis.
TL;DRThree assigned radiologists with different experience levels achieved generally poor inter‑reader agreement using the PI-RADS version 2.1 guideline, and varying expertise did not significantly influence PI-RADS 3 evaluat…
FULLTEXT: LI-RADS -
Development and validation of a nomogram combining PI-RADS v2.1 and clinical indicators for the diagnosis of prostate cancer in patients with PSA ≤ 20 ng/mL.
[PURPOSE] This investigation focused on developing a predictive clinical tool that combines biparametric MRI-derived PI-RADS v2.1 assessments with patient-specific biomarkers. The model was designed to optimize prostate cancer detection rel…
FULLTEXT: LI-RADS -
Detection of clinically significant prostate cancer using targeted MRI-informed microultrasound biopsy.
TL;DRThis retrospective study demonstrates successful implementation of microUS-guided biopsy, with similar rates of identification of csPCa compared to historical data using mpMRI-US fusion, supporting the combined approach …
FULLTEXT: LI-RADS -
Quantitative synthetic MRI improves peripheral zone prostate cancer detection beyond PI-RADS v2.1.
TL;DRQuantitative SyMRI provides reproducible, contrast-free biomarkers that significantly enhance detection of peripheral zone prostate cancer beyond PI-RADS v2.1, and should be interpreted as exploratory and validated in la…
FULLTEXT: LI-RADS -
Evaluation of AI for prostate cancer detection in biparametric-MRI screening population data.
TL;DRA prostate MRI dataset from a screening population with histological confirmation was curated and evaluated with AI, and the neural network trained and tested on this data produced lower specificities than the radiologis…
FULLTEXT: LI-RADS -
Incremental Predictive Value of the Oncotype Genomic Prostate Score for Adverse Pathology in Active Surveillance Candidates.
TL;DRWhether GPS adds predictive value beyond established clinical variables for adverse pathology at radical prostatectomy in active surveillance‐eligible patients in active surveillance‐eligible patients is assessed.
FULLTEXT: LI-RADS -
Evaluation of Loss of the Y Chromosome in Peripheral Blood as a Biomarker for Prostate Cancer.
TL;DRResearch proposes that the loss of the Y chromosome (LOY) may affect the occurrence and development of prostate cancer, aiming to assess its potential as a diagnostic biomarker to improve the accuracy of prostate cancer …
FULLTEXT: LI-RADS -
A Dual-Threshold Strategy Enables Reliable Biopsy-Free Diagnosis of High-Risk Prostate Cancer.
TL;DRIt is evaluated whether combining pre‐operative clinical indicators and ¹⁸F‐PSMA‐1007 PET/CT could non‐invasively stratify HRPCa risk.
FULLTEXT: LI-RADS -
In the Era of mpMRI and PSMA PET/CT: Does Digital Rectal Examination Still Matter?
TL;DRThis study aimed to reassess the diagnostic value of DRE in the context of contemporary imaging tools, particularly mpMRI and PSMA PET/CT.
FULLTEXT: LI-RADS -
Diagnostic value of MRI-ultrasound fusion-targeted prostate biopsy for non-index lesions combined with the index lesion biopsy.
[PURPOSE] While the clinical value of magnetic resonance imaging (MRI)-ultrasound fusion-targeted prostate biopsy (TB) for index lesions (ILs) has been established, the utility of TB for non-index lesions (nILs) remains unclear. We evaluate…
FULLTEXT: LI-RADS -
Implications for Radiation Microboosting Based on Pathology Correlations With Prostate-Specific Membrane Antigen and Multiparametric Magnetic Resonance Imaging Findings.
[PURPOSE] Prostate-specific membrane antigen (PSMA) positron emission tomography and multiparametric magnetic resonance imaging (mpMRI) are used to contour the dominant intraprostatic lesion (DIL) when incorporating a microboost. However, i…
FULLTEXT: LI-RADS -
Optimising contrast-enhanced ultrasound (CEUS) Liver Imaging Reporting and Data System (LI-RADS) for hepatocellular carcinoma diagnosis in non-cirrhotic hepatitis B virus infection patients: incorporating alpha-fetoprotein or adjusting washout criteria.
[AIM] To improve the diagnostic performance of contrast-enhanced ultrasound (CEUS) Liver Imaging Reporting and Data System (LI-RADS) for hepatocellular carcinoma (HCC) in non-cirrhotic hepatitis B virus (NC-HBV) patients by integrating seru…
FULLTEXT: LI-RADS -
ESR Essentials: thyroid imaging-practice recommendations by the European Society of Head and Neck Radiology.
TL;DRTo implement recommendations, radiologists should adopt standardised US reporting systems, apply evidence-based criteria for further workup, and collaborate closely with referring clinicians to avoid unnecessary biopsies…
FULLTEXT: LI-RADS -
MRI after Interventional Therapy of Hepatocellular Carcinoma: Typical Changes over Time.
TL;DRThe complementary effect of using immunotherapies alongside other treatments and the need to identify the putative biomarkers to predict therapeutic activity and monitor the response to treatment are explained.
FULLTEXT: LI-RADS -
The PRIMARY Scoring System on PSMA PET for Clinically Significant Prostate Cancer Detection: A Systematic Review and Meta-Analysis.
TL;DRIon channels and extrachromosomal DNA have emerged as key drivers of such adaptive processes by influencing signaling, metabolism, and immune interactions.
FULLTEXT: LI-RADS