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Bidirectional Mendelian randomization identifies differential causal associations between inflammatory cytokines and lung cancer subtypes.

Discover oncology 2026 Vol.17(1)

Sun M, Gao X

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Mendelian randomization study on relationships between inflammatory factors and lung cancer risk.

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APA Sun M, Gao X (2026). Bidirectional Mendelian randomization identifies differential causal associations between inflammatory cytokines and lung cancer subtypes.. Discover oncology, 17(1). https://doi.org/10.1007/s12672-026-04615-y
MLA Sun M, et al.. "Bidirectional Mendelian randomization identifies differential causal associations between inflammatory cytokines and lung cancer subtypes.." Discover oncology, vol. 17, no. 1, 2026.
PMID 41665765

Abstract

Mendelian randomization study on relationships between inflammatory factors and lung cancer risk. Bidirectional two-sample Mendelian randomization approach, utilizing Genome-Wide Association Studies data for two primary lung cancer subtypes: non-small cell lung cancer and small cell lung cancer. The study elucidated the potential causal relationship between specific inflammatory factors and the risk of non-small cell lung cancer and small cell lung cancer.

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