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Mechanistic insights into voriconazole-exacerbated selpercatinib-induced thrombocytopenia: a pharmacokinetic interaction case report.

증례보고 1/5 보강
Frontiers in oncology 📖 저널 OA 100% 2021: 15/15 OA 2022: 98/98 OA 2023: 60/60 OA 2024: 189/189 OA 2025: 1004/1004 OA 2026: 620/620 OA 2021~2026 2026 Vol.16() p. 1680060
Retraction 확인
출처

PICO 자동 추출 (휴리스틱, conf 2/4)

유사 논문
P · Population 대상 환자/모집단
환자: advanced lung cancer after 4 days of concurrent treatment with selpercatinib and voriconazole
I · Intervention 중재 / 시술
추출되지 않음
C · Comparison 대조 / 비교
추출되지 않음
O · Outcome 결과 / 결론
Subsequent treatment did not have any further adverse reactions. This case suggests that doctors and clinician pharmacists should be aware of the potential interaction between selpercatinib and voriconazole, avoid the use of CYP3A4 inhibitors during selpercatinib treatment, and pay attention to dose adjustment.

Tang H, Zhou Z, Zhang Y, Chen W, Meng J, Li G


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