Determinants of cardiovascular health management in patients with breast cancer at high risk for cardiotoxicity: A qualitative study.

[PURPOSE] Effective cardiovascular health (CVH) management plays a crucial role in preventing cardiovascular disease and promoting both longevity and quality of life. However, its implementation among breast cancer (BC) patients remains challenging, particularly for those at high risk of cardiotoxicity due to cancer therapy. This study aimed to explore the factors influencing CVH management among BC patients at high risk for cardiotoxicity.

[METHODS] Face-to-face semi-structured individual interviews were conducted with BC patients at high risk of cardiotoxicity. Thematic analysis method was used for data analysis.

[RESULTS] A total of 24 participants aged 33 to 72 were included. Four key themes influencing CVH management were identified: (1) Knowledge and beliefs: Barriers included limited understanding of CVH, inconsistent confidence in sustaining management, and conflicts between health goals and role obligations; while high outcome expectancy served as a key motivator; (2) Self-regulation skill and ability: Challenges occurred in setting goals and action plans, self-monitoring, and prioritizing cancer care over CVH; though effective emotional regulation facilitated management; (3) Social facilitation: Emotional support promoted CVH management; whereas insufficient supervision and limited professional guidance acted as barriers; (4) Other dimensions: Physical discomfort, information-related stress, financial strain and sociocultural constraints further hindered CVH management.

[CONCLUSIONS] These findings highlight the complex and interconnected factors shaping CVH management among BC patients at high risk for cardiotoxicity. Understanding these influences can inform the design of tailored interventions and sustained support systems to improve CVH management, thereby optimizing survivorship care and enhancing quality of life.