Transcriptomic profile and gene expression of human breast cancer cell lines treated with herbal extract of leaves.
1/5 보강
(CN) is traditionally used in medicine, but its apoptotic effects on breast cancer cells remain unclear.
APA
Md Toha Z, Haron N, et al. (2026). Transcriptomic profile and gene expression of human breast cancer cell lines treated with herbal extract of leaves.. Journal of Asian natural products research, 1-21. https://doi.org/10.1080/10286020.2026.2625174
MLA
Md Toha Z, et al.. "Transcriptomic profile and gene expression of human breast cancer cell lines treated with herbal extract of leaves.." Journal of Asian natural products research, 2026, pp. 1-21.
PMID
41643046 ↗
Abstract 한글 요약
(CN) is traditionally used in medicine, but its apoptotic effects on breast cancer cells remain unclear. This study investigated the apoptotic potential of CN dichloromethane leaf extract (CNDCM) in MCF-7 cells using RNA-Seq analysis. Differential gene expression analysis identified 843 genes, with 395 upregulated and 448 downregulated. Gene ontology and KEGG pathway analyses revealed apoptosis-related pathways. Key apoptosis-associated genes, including , and , were further validated by RT-qPCR. These findings suggest CNDCM as a potential candidate for breast cancer therapy.
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🏷️ 같은 키워드 · 무료전문 — 이 논문 MeSH/keyword 기반
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