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Unrevealing the Multifaceted Role of Resveratrol as Potential Antioxidant and Anticancer Agent: Molecular Mechanism and Future Perspectives.

Chemistry & biodiversity 2026 Vol.23(3) p. e03280

Sharma A, Kumar A, Chaudhary RP, Singh AK, Singh H, Kumar P

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The non-flavonoid polyphenol, resveratrol, has a wide range of biological properties and the potential to form many different products.

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APA Sharma A, Kumar A, et al. (2026). Unrevealing the Multifaceted Role of Resveratrol as Potential Antioxidant and Anticancer Agent: Molecular Mechanism and Future Perspectives.. Chemistry & biodiversity, 23(3), e03280. https://doi.org/10.1002/cbdv.202403280
MLA Sharma A, et al.. "Unrevealing the Multifaceted Role of Resveratrol as Potential Antioxidant and Anticancer Agent: Molecular Mechanism and Future Perspectives.." Chemistry & biodiversity, vol. 23, no. 3, 2026, pp. e03280.
PMID 41790488

Abstract

The non-flavonoid polyphenol, resveratrol, has a wide range of biological properties and the potential to form many different products. Resveratrol acts on multiple biological targets and is a potent antioxidant in a variety of pathological conditions. The aim of this review is to provide a comprehensive overview of the latest research on the chemistry, biosynthetic pathways, methods of preparation, and biological properties, specifically, anticancer and antioxidant properties of resveratrol, as well as the nuances of pharmacokinetics with a special emphasis on bio-enhancement approaches. Insights into different delivery systems showed the dynamic landscape of resveratrol delivery and addressed the challenges and innovations in improving bioavailability. This review will provide a comprehensive overview of resveratrol's potential as an antioxidant and anticancer agent, its pharmacokinetics, and extraction methods, as well as various synthetic routes for its synthesis. Therefore, it will pave the way for future research and clinical applications in combating cancer and oxidative stress-related diseases and contribute to advancements in healthcare and medicine.

MeSH Terms

Resveratrol; Humans; Antioxidants; Neoplasms; Antineoplastic Agents, Phytogenic; Animals; Antineoplastic Agents; Oxidative Stress; Cell Proliferation

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