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Deciphering the Cellular and Metabolic Landscape of Lymph Node Metastasis in Breast Cancer Using Single-Cell and Spatial Multi-Omics.

2/5 보강

The American journal of pathology 📖 저널 OA 63.3% 2023~2026 2026 Vol.196(4) p. 1028-1048 Single-cell and spatial transcriptom

TL;DR The cellular architecture and regulatory interplay underlying LN metastasis in BRCA is discussed, offering novel insights that may inform targeted therapeutic strategies for patients with metastatic disease.

PICO 자동 추출 (휴리스틱, conf 2/4)

유사 논문

P · Population 대상 환자/모집단

환자: metastatic disease

I · Intervention 중재 / 시술

추출되지 않음

C · Comparison 대조 / 비교

추출되지 않음

O · Outcome 결과 / 결론

These results were validated using spatial transcriptomics data of four metastatic LN tissue sections from an integrated single-cell RNA-sequencing cohort. Collectively, this study discussed the cellular architecture and regulatory interplay underlying LN metastasis in breast cancer, offering novel insights that may inform targeted therapeutic strategies for patients with metastatic disease.

OpenAlex 토픽 · Single-cell and spatial transcriptomics Immune cells in cancer Cancer Immunotherapy and Biomarkers

Zhu R, Jiang G, Shen J, Gong C, Shan H, Liang T

PubMed ↗ DOI ↗ BibTeX ↓ RIS ↓

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