Panitumumab-IRDye800 Improves Laryngeal Tumor Mapping During Transoral Laser Microsurgery.
Abstract
Transoral laser microsurgery represents the primary surgical modality for early laryngeal cancers with oncologic outcomes equivalent to radiotherapy. Accurate tumor mapping and margin assessment can be difficult, however, particularly during piecemeal or ablative resections, and for tumors with a wider geographic footprint. Tumor-targeted fluorescence-guided surgery in patients with head and neck cancer has empirically improved tumor and margin identification; this case details, for the first time, a fluorescence-guided surgical resection of a T2N0M0 transglottic tumor using panitumumab-IRDye800, an epidermal growth factor receptor monoclonal antibody covalently linked to near-infrared (NIR) dye. Laryngoscope, 134:1837-1841, 2024.
추출된 의학 개체 (NER)
| 유형 | 영어 표현 | 한국어 / 풀이 | UMLS CUI | 출처 | 등장 |
|---|---|---|---|---|---|
| 시술 | microsurgery
|
미세수술 | dict | 2 | |
| 질환 | Tumor
|
C0027651
Neoplasms
|
scispacy | 1 | |
| 질환 | laryngeal cancers
|
C0007107
Malignant neoplasm of larynx
|
scispacy | 1 | |
| 질환 | tumors
|
C0027651
Neoplasms
|
scispacy | 1 | |
| 질환 | head and neck cancer
|
C0278996
Malignant Head and Neck Neoplasm
|
scispacy | 1 | |
| 질환 | transglottic tumor
|
C0585360
Transglottic tumor
|
scispacy | 1 | |
| 질환 | Laryngeal Tumor
|
scispacy | 1 | ||
| 질환 | T2N0M0 transglottic tumor
|
scispacy | 1 | ||
| 기타 | Panitumumab-IRDye800
|
scispacy | 1 | ||
| 기타 | patients
|
scispacy | 1 | ||
| 기타 | epidermal growth factor receptor monoclonal antibody covalently
|
scispacy | 1 |
MeSH Terms
Humans; Laryngeal Neoplasms; Panitumumab; Carcinoma, Squamous Cell; Microsurgery; Laser Therapy; Lasers; Glottis; Retrospective Studies; Neoplasm Staging; Indoles
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