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Etiology and Management of Intraoperative Free Flap Failure.
[BACKGROUND] Intraoperative free flap failure necessitates prompt intraoperative decision-making on alternative reconstructive strategies. In this study, we investigate the etiology and management of intraoperative flap loss. [METHODS] Ret…
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Flow-Through Flaps as a Robust Method for Advanced Free Flap Reconstruction in the Head and Neck: A Multi-Institutional Experience.
[BACKGROUND] Flow-through flaps (FTFs) are an advanced technique in which a free flap is anastomosed to the pedicle of another free flap to reconstruct extensive head and neck defects when recipient vessels are scarce. [METHODS] A multi-in…
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Aggressive Head and Neck Squamous Cell Carcinoma in the Setting of GATA2 Deficiency.
[BACKGROUND] GATA2 deficiency is a rare genetic disorder associated with hematologic, infectious, and neoplastic complications. We report a case of a patient with GATA2 deficiency who developed aggressive squamous cell carcinoma (SCC) of th…
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Outcomes of Head and Neck Free Tissue Transfer in Renal Failure Patients.
[OBJECTIVE] To assess if there is increased risk of free flap failure in renal failure patients undergoing head and neck reconstruction. We seek to primarily assess free flap outcomes based on stages of chronic kidney disease (CKD) and seco…
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Microvascular Free Flap Outcomes in Maxillectomy Defects from Invasive Fungal Sinusitis.
[OBJECTIVES] Microvascular free tissue transfer is routinely used for reconstructing midface defects in patients with malignancy, however, studies regarding reconstructive outcomes in invasive fungal sinusitis (IFS) are lacking. We aim to d…
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Panitumumab-IRDye800 Improves Laryngeal Tumor Mapping During Transoral Laser Microsurgery.
Transoral laser microsurgery represents the primary surgical modality for early laryngeal cancers with oncologic outcomes equivalent to radiotherapy. Accurate tumor mapping and margin assessment can be difficult, however, particularly durin…
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Microvascular reconstruction of medication related osteonecrosis of the head and neck.
[BACKGROUND] Medication related osteonecrosis of the jaw (MRONJ) requiring free flap (FF) reconstruction is uncommon with limited reported findings. [METHODS] Multicenter, retrospective case series of 49 consecutive adult patients presenti…
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Comparing the Outcomes of Osteocutaneous Radial Forearm and Fibula Free Flaps in the Reconstruction of Mandibular Osteoradionecrosis.
[BACKGROUND] This study compares the outcomes of osteocutaneous radial forearm free flap (OC-RFFF) and fibula free flap (FFF) reconstruction of mandibular osteoradionecrosis (ORN). [METHODS] Retrospective review of patients undergoing OC-R…
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Free Flap Outcomes for Head and Neck Surgery in Patients with COVID-19.
[INTRODUCTION] Coronavirus disease 2019 (COVID-19) affects the vascular system, subjecting patients to a hypercoagulable state. This is of particular concern for the success of microvascular free flap reconstruction. This study aims to repo…
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Free flap reconstruction following head and neck trauma.
[BACKGROUND] Free flap (FF) reconstruction of traumatic injuries to the head and neck is uncommon. [METHODS] Multi-institutional retrospective case series of patients undergoing FF reconstruction for a traumatic injury (n = 103). [RESULTS…
- Notes from the Field: Illnesses After Administration of Presumed Counterfeit Botulinum Toxin in Nonmedical Settings - Tennessee and New York City, March 2024.
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Post-operative Outcomes in Pediatric Patients Following Facial Reconstruction With Fibula Free Flaps.
[EDUCATIONAL OBJECTIVE] Assess outcomes of pediatric facial reconstruction with fibula free flaps. [OBJECTIVES] Free flap reconstruction of complex maxillofacial defects in pediatric patients is rare. Post-operative complications, donor si…
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Effect of Perioperative Antithrombotics on Head and Neck Microvascular Free Flap Survival After Anastomotic Revision.
[OBJECTIVE] To determine if antithrombotic therapy improves head and neck microvascular free flap survival following anastomotic revision. [STUDY DESIGN] A retrospective review of all patients with microvascular free tissue transfer to the…
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Impact of preoperative and intraoperative management on outcomes in osteoradionecrosis requiring free flap reconstruction.
[BACKGROUND] Perioperative management of advanced osteoradionecrosis of the head and neck requiring free flap (FF) reconstruction varies. Our objectives included assessment of practice patterns and outcomes. [METHODS] Multi-institutional, …
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Microvascular Reconstruction of Osteonecrosis: Assessment of Long-term Quality of Life.
[OBJECTIVE] Review long-term clinical and quality-of-life outcomes following free flap reconstruction for osteonecrosis. [STUDY DESIGN] Retrospective multi-institutional review. [SETTING] Tertiary care centers. [METHODS] Patients include…
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Absorption of 17 beta-estradiol in a neovagina constructed from the peritoneum.
Estrogen absorption from the neovagina was studied by administering 2.0 mg of micronized 17 beta-estradiol (E2) neovaginally to 6 patients. The neovagina in each patient was constructed by using the peritoneum from the pouch of Douglas. A m…