The effect of preoperative oral carbohydrate on the perioperative period of fibula free flap surgery in patients with oral cancer: a retrospective study.
TL;DR
Preoperative oral carbohydrates improve comfort and stabilize blood glucose levels in patients undergoing oral cancer fibula flap surgery, positively influencing perioperative management.
OpenAlex 토픽 ·
Enhanced Recovery After Surgery
Oral health in cancer treatment
Cleft Lip and Palate Research
Preoperative oral carbohydrates improve comfort and stabilize blood glucose levels in patients undergoing oral cancer fibula flap surgery, positively influencing perioperative management.
- p-value p < 0.0001
- p-value p = 0.0003
APA
Chunyun Liu, Xiaohua Liu, et al. (2025). The effect of preoperative oral carbohydrate on the perioperative period of fibula free flap surgery in patients with oral cancer: a retrospective study.. Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 33(10), 836. https://doi.org/10.1007/s00520-025-09886-9
MLA
Chunyun Liu, et al.. "The effect of preoperative oral carbohydrate on the perioperative period of fibula free flap surgery in patients with oral cancer: a retrospective study.." Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, vol. 33, no. 10, 2025, pp. 836.
PMID
40913154
Abstract
[OBJECTIVE] This study examines the effects of preoperative oral carbohydrates on the perioperative period of Fibula Free Flap surgery in oral cancer patients, aiming to enhance postoperative recovery.
[METHODS] The study involved 89 patients who underwent fibula flap reconstruction surgery from January to December 2023. Patients were divided into control and experimental groups based on admission time. The control group followed standard fasting guidelines, while the experimental group received 800 mL and 200 mL of carbohydrates solution orally at 10 and 2 h pre-surgery, respectively. Data collected for both groups included comfort levels, blood glucose, surgical duration, intraoperative blood loss, fluid replacement, albumin, prealbumin, hemoglobin, PCT, IL-6, flap crisis, wound infection, bleeding, thrombosis, gastrointestinal reactions, extubation time, hospital stay, and total cost. All data were statistically analyzed.
[RESULTS] The experimental group reported significantly lower thirst and hunger one hour pre-surgery (p < 0.0001) and had lower blood glucose levels one day post-surgery (p = 0.0003) compared to the control group. No significant differences were observed in other preoperative or postoperative measures.
[CONCLUSIONS] Preoperative oral carbohydrates improve comfort and stabilize blood glucose levels in patients undergoing oral cancer fibula flap surgery, positively influencing perioperative management. This approach is beneficial for patients receiving this type of surgery.
[METHODS] The study involved 89 patients who underwent fibula flap reconstruction surgery from January to December 2023. Patients were divided into control and experimental groups based on admission time. The control group followed standard fasting guidelines, while the experimental group received 800 mL and 200 mL of carbohydrates solution orally at 10 and 2 h pre-surgery, respectively. Data collected for both groups included comfort levels, blood glucose, surgical duration, intraoperative blood loss, fluid replacement, albumin, prealbumin, hemoglobin, PCT, IL-6, flap crisis, wound infection, bleeding, thrombosis, gastrointestinal reactions, extubation time, hospital stay, and total cost. All data were statistically analyzed.
[RESULTS] The experimental group reported significantly lower thirst and hunger one hour pre-surgery (p < 0.0001) and had lower blood glucose levels one day post-surgery (p = 0.0003) compared to the control group. No significant differences were observed in other preoperative or postoperative measures.
[CONCLUSIONS] Preoperative oral carbohydrates improve comfort and stabilize blood glucose levels in patients undergoing oral cancer fibula flap surgery, positively influencing perioperative management. This approach is beneficial for patients receiving this type of surgery.
추출된 의학 개체 (NER)
| 유형 | 영어 표현 | 한국어 / 풀이 | UMLS CUI | 출처 | 등장 |
|---|---|---|---|---|---|
| 시술 | flap
|
피판재건술 | dict | 3 | |
| 시술 | free flap
|
피판재건술 | dict | 2 | |
| 해부 | oral
|
scispacy | 1 | ||
| 해부 | blood glucose
|
scispacy | 1 | ||
| 해부 | blood
|
scispacy | 1 | ||
| 해부 | oral carbohydrates
|
scispacy | 1 | ||
| 합병증 | wound infection
|
감염 | dict | 1 | |
| 합병증 | wound
|
scispacy | 1 | ||
| 합병증 | gastrointestinal
|
scispacy | 1 | ||
| 약물 | carbohydrate
|
C0007004
Carbohydrates
|
scispacy | 1 | |
| 약물 | oral cancer
|
C0153381
Malignant neoplasm of mouth
|
scispacy | 1 | |
| 약물 | glucose
|
C0017725
glucose
|
scispacy | 1 | |
| 약물 | carbohydrates
|
scispacy | 1 | ||
| 질환 | oral cancer
|
C0153381
Malignant neoplasm of mouth
|
scispacy | 1 | |
| 질환 | intraoperative blood loss
|
scispacy | 1 | ||
| 질환 | infection
|
C0009450
Communicable Diseases
|
scispacy | 1 | |
| 질환 | bleeding
|
C0019080
Hemorrhage
|
scispacy | 1 | |
| 질환 | thrombosis
|
C0040053
Thrombosis
|
scispacy | 1 | |
| 질환 | gastrointestinal reactions
|
scispacy | 1 | ||
| 질환 | thirst
|
C0039971
Thirst
|
scispacy | 1 | |
| 질환 | lower blood glucose
|
scispacy | 1 | ||
| 질환 | oral cancer fibula flap surgery
|
scispacy | 1 | ||
| 질환 | oral cancer patients
|
scispacy | 1 | ||
| 질환 | oral cancer fibula flap
|
scispacy | 1 | ||
| 기타 | fibula free flap
|
scispacy | 1 | ||
| 기타 | fibula flap
|
scispacy | 1 | ||
| 기타 | albumin
|
scispacy | 1 | ||
| 기타 | prealbumin
|
scispacy | 1 | ||
| 기타 | hemoglobin
|
scispacy | 1 | ||
| 기타 | IL-6
|
scispacy | 1 |
MeSH Terms
Humans; Female; Male; Retrospective Studies; Middle Aged; Free Tissue Flaps; Mouth Neoplasms; Aged; Preoperative Care; Fibula; Blood Glucose; Adult; Perioperative Period; Plastic Surgery Procedures; Dietary Carbohydrates
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