The use of etanercept for treatment of toxic epidermal necrolysis when toxic shock syndrome is in the differential.
1/5 보강
Toxic shock syndrome (TSS) can sometimes mimic Steven Johnsons syndrome/toxic epidermal necrolysis (SJS/TEN).
APA
So N, Leavitt E, et al. (2018). The use of etanercept for treatment of toxic epidermal necrolysis when toxic shock syndrome is in the differential.. Dermatologic therapy, 31(5), e12684. https://doi.org/10.1111/dth.12684
MLA
So N, et al.. "The use of etanercept for treatment of toxic epidermal necrolysis when toxic shock syndrome is in the differential.." Dermatologic therapy, vol. 31, no. 5, 2018, pp. e12684.
PMID
30175438 ↗
Abstract 한글 요약
Toxic shock syndrome (TSS) can sometimes mimic Steven Johnsons syndrome/toxic epidermal necrolysis (SJS/TEN). Tumor necrosis factor (TNF) alpha is thought to play a role in the pathogenesis of both TSS and SJS/TEN. Etanercept, a TNF-alpha inhibitor has been recently shown to treat and decrease mortality of SJS/TEN. We report a 51-year-old female with history of SJS presenting with painful skin and bullae 2 days following cystoscopy with botulinum toxin injection into the bladder. Due to initial concern for SJS/TEN, the patient was treated with 50 mg of subcutaneous etanercept. Punch biopsies were not consistent with SJS, and the patient fulfilled five out of five criteria for a confirmed case of TSS. The patient ultimately had a favorable outcome despite etanercept treatment. Ultimately, TNF-alpha antagonists are an emerging therapy to treat SJS/TEN, and are unlikely to worsen TSS prognosis. Given that etanercept can be used to successfully treat SJS/TEN and TNF-alpha levels are elevated in TSS, if a dermatologist chooses to treat TEN with etanercept, consideration of TSS on the differential should not necessarily exclude etanercept as a reasonable treatment option.
추출된 의학 개체 (NER)
전체 NER 표 보기
| 유형 | 영어 표현 | 한국어 / 풀이 | UMLS CUI | 출처 | 등장 |
|---|---|---|---|---|---|
| 시술 | botulinum toxin
|
보툴리눔독소 주사 | dict | 1 | |
| 해부 | subcutaneous
|
피하조직 | dict | 1 | |
| 합병증 | necrosis
|
괴사 | dict | 1 |
🏷️ 키워드 / MeSH 📖 같은 키워드 OA만
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