Interleukin-11: A pivotal player and potential therapeutic target in prostate cancer.
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OpenAlex 토픽 ·
Cytokine Signaling Pathways and Interactions
Chemokine receptors and signaling
Virus-based gene therapy research
Interleukin-11 (IL-11), a pleiotropic cytokine belonging to the interleukin-6 (IL-6) family, is implicated in the initiation and progression of various malignancies.
APA
Jinghua Zhong, Xiaolu Duan, et al. (2026). Interleukin-11: A pivotal player and potential therapeutic target in prostate cancer.. Current urology, 20(3), 174-179. https://doi.org/10.1097/CU9.0000000000000323
MLA
Jinghua Zhong, et al.. "Interleukin-11: A pivotal player and potential therapeutic target in prostate cancer.." Current urology, vol. 20, no. 3, 2026, pp. 174-179.
PMID
41969323 ↗
Abstract 한글 요약
Interleukin-11 (IL-11), a pleiotropic cytokine belonging to the interleukin-6 (IL-6) family, is implicated in the initiation and progression of various malignancies. Recent studies revealed that IL-11 plays multifaceted roles in prostate cancer, contributing to tumor cell proliferation, castration resistance, bone metastasis, and chemotherapeutic resistance. Interleukin-11 has emerged as a promising target for both diagnostic and therapeutic strategies. This review outlines the molecular structure and biological functions of IL-11; summarizes its role in early diagnosis, prognostic evaluation, tumor progression, and therapeutic intervention for prostate cancer; and explores its potential as a novel therapeutic target.
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