Isorhamnetin: A review of pharmacological effects.
💡 한 문장 핵심
Isorhamnetin: 약리학적 효과에 관한 고찰.
4/5 보강
TL;DR
The manuscript reviewed the pharmacological effects of isorhamnetin and related mechanisms of action for the development of its medicinal properties further and highlighted the need for detailed scientific validation on its mechanism of action.
연도별 인용 (2020–2026) · 합계 517
OpenAlex 토픽 ·
Phytochemical and Pharmacological Studies
Medicinal plant effects and applications
Abstract 🌐 Abstract
Isorhamnetin is one of the most important active ingredients in the fruits of Hippophae rhamnoides L. and the leaves of Ginkgo biloba L., which possesses extensive pharmacological activities. At present, there have been numerous investigations on isorhamnetin, which has the effects of cardiovascular and cerebrovascular protection, anti-tumor, anti-inflammatory, anti-oxidation, organ protection, prevention of obesity, etc. The related mechanisms involve the regulation of PI3K/AKT/PKB, NF-κB, MAPK and other signaling pathways as well as the expression of related cytokines and kinases. Isorhamnetin has a high value of development and application. However, the investigations on its mechanism of action are limited and lack of detailed scientific validation. The manuscript reviewed the pharmacological effects of isorhamnetin and related mechanisms of action for the development of its medicinal properties further.
The manuscript reviewed the pharmacological effects of isorhamnetin and related mechanisms of action for the development of its medicinal properties further and highlighted the need for detailed scien
APA 7
Gong, G., Guan, Y. Y., Zhang, Z. L., Rahman, K., Wang, S. J., Zhou, S., Luan, X., & Zhang, H. (2020). Isorhamnetin: A review of pharmacological effects.. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 128, 110301. https://doi.org/10.1016/j.biopha.2020.110301
Vancouver
Gong G, Guan YY, Zhang ZL, Rahman K, Wang SJ, Zhou S, et al. Isorhamnetin: A review of pharmacological effects. Biom. & phar. = Biom. & phar.. 2020;128:110301. doi:10.1016/j.biopha.2020.110301
AMA 11
Gong G, Guan YY, Zhang ZL, Rahman K, Wang SJ, Zhou S, et al. Isorhamnetin: A review of pharmacological effects. Biom. & phar. = Biom. & phar.. 2020;128:110301. doi:10.1016/j.biopha.2020.110301
Chicago
Gong, G., Guan, Y. Y., Zhang, Z. L., Rahman, K., Wang, S. J., Zhou, S., Luan, X., and Zhang, H.. 2020. "Isorhamnetin: A review of pharmacological effects." Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 128: 110301. https://doi.org/10.1016/j.biopha.2020.110301
MLA 9
Gong, G., et al. "Isorhamnetin: A review of pharmacological effects." Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, vol. 128, 2020, pp. 110301. doi:10.1016/j.biopha.2020.110301.
PMID
32502837 ↗
추출된 의학 개체 (NER)
전체 NER 표 보기
| 유형 | 영어 표현 | 한국어 / 풀이 | UMLS CUI | 출처 | 등장 |
|---|---|---|---|---|---|
| 해부 | fruits
|
과일 | scispacy | 1 | |
| 해부 | Hippophae rhamnoides L.
|
scispacy | 1 | ||
| 해부 | leaves
|
잎 | scispacy | 1 | |
| 해부 | Ginkgo biloba L.
|
scispacy | 1 | ||
| 해부 | organ
|
장기 | scispacy | 1 | |
| 약물 | Isorhamnetin
|
scispacy | 1 | ||
| 약물 | Ginkgo biloba
|
은행나무 | scispacy | 1 | |
| 약물 | ginkgo
|
은행잎 | dict | 1 | |
| 질환 | cardiovascular and cerebrovascular protection
|
scispacy | 1 | ||
| 질환 | obesity
|
비만 | scispacy | 1 | |
| 질환 | anti-tumor
|
항종양 | scispacy | 1 | |
| 기타 | cerebrovascular
|
scispacy | 1 | ||
| 기타 | MAPK
|
미토겐활성화단백질키나아제(MAPK) | scispacy | 1 |
🏷️ 키워드 / MeSH 📖 같은 키워드 OA만
🤖 이 논문을 인용한 AI 인사이트 · 2건
📰 주간
🏷 암·종양
은행잎 — 항산화·항암 다중표적
P: 은행잎 성분 및 추출물의 항암·신경계 효과를 평가한 in vitro/in vivo 모델. 무작위배정 임상 데이터는 부족하며 세포·동물 모델에 집 O: 항산화 활성, 항암 기전(Nrf2/HO-1 축 교란을 통한 ferroptosis 및 cisplatin 감작), 신경염증 조절 등 분자 경로 지표
📰 주간
🏷 암·종양
은행잎 — 신경보호·항암 다층 약리
P: 알츠하이머병 등 신경퇴행성 질환 환자 및 종양 in vitro/in vivo 모델, 그리고 응용 화학·유전체 연구 대상 은행잎 자원. O: 신경보호 효과, 항암 활성(ferroptosis 유도), Nrf2/HO-1 축 조절 등 기전적 지표와 secondary metabolite bi
이 논문은 위 AI 빅데이터 분석에 인용된 근거 논문입니다.
인용 관계
그래프 OA 노드: 0/2 (0%)
· 참조 0편 · 후속 0편
같은 제1저자의 인용 많은 논문 (5)
- Danggui Buxue Tang improves therapeutic efficacy of doxorubicin in triple negative breast cancer via ferroptosis.
- Urban-rural disparities in education's mediating role between digital engagement and depression among Chinese older adults.
- Clinical Trial Patient Matching: A Real-Time, Common Data Model and Artificial Intelligence-Driven System for Semiautomated Patient Prescreening in Cancer Clinical Trials.
- Targeting ferroptosis with flavonoids for cancer therapy: Mechanisms and opportunities.
- Therapeutic Targets and Molecular Mechanisms of Calycosin in the Treatment of Depression: Insights From Chronic Mild Stress Animal Models.
🏷️ 같은 키워드 · 무료전문 — 이 논문 MeSH/keyword 기반
📖 비슷한 OA 논문 — 같은 카테고리, 무료 전문 가능
- Interventions for vitiligo.
- Ginkgetin suppresses ovarian cancer growth through inhibition of JAK2/STAT3 and MAPKs signaling pathways.
- Ginkgolide B facilitates muscle regeneration via rejuvenating osteocalcin-mediated bone-to-muscle modulation in aged mice.
-
Metabolic interaction between biflavonoids in Ginkgo biloba leaves and tacrolimus.
TL;DRThe results showed that long‐term combination of G. biloba leaves and tacrolimus may cause drug–drug interactions and the molecular mechanism of inhibition was explored by molecula…
- Clinical and economic analysis of Gastrodin injection for dizziness or vertigo: a retrospective cohort study based on electronic health records in China.