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Newly Identified Transcriptomic Biomarkers and Gene Signature of Pathological Complete Response to Induction Chemoimmunotherapy in Locally Advanced Head and Neck Squamous Cell Carcinoma.

1/5 보강

MedComm 📖 저널 OA 100% 2024~2026 2026 Vol.7(1) p. e70582 OA

PICO 자동 추출 (휴리스틱, conf 2/4)

유사 논문

P · Population 대상 환자/모집단

42 patients achieved pCR, while 35 had residual disease (RD).

I · Intervention 중재 / 시술

추출되지 않음

C · Comparison 대조 / 비교

추출되지 않음

O · Outcome 결과 / 결론

Logistic regression models indicated the significance of T and B cells and IFN-gamma signaling in predicting pCR. Furthermore, a new CheckRad-7-gene signature, with an AUC of 0.902 in the training cohort, effectively predicted pCR and survival, serving as a robust biomarker for prognosis and treatment response in HNSCC.

Zhou JG, Eckstein M, Wang H, Lan T, Frey B, Li X

📖 무료 전문 🟢 PMC 전문 PMC12802090 🔓 OA PDF unpaywall · cc-by

PubMed ↗ DOI ↗ BibTeX ↓ RIS ↓

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