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CREB3L1 promotes tumor growth and metastasis of anaplastic thyroid carcinoma by remodeling the tumor microenvironment.

1/5 보강

Molecular cancer 📖 저널 OA 96.9% 2022~2026 2022 Vol.21(1) p. 190

PICO 자동 추출 (휴리스틱, conf 2/4)

유사 논문

P · Population 대상 환자/모집단

환자: thyroid cancer

I · Intervention 중재 / 시술

추출되지 않음

C · Comparison 대조 / 비교

추출되지 않음

O · Outcome 결과 / 결론

Moreover, KPNA2 mediated the nuclear translocation of CREB3L1, thus allowing it to activate downstream ECM signaling. These results demonstrate that CREB3L1 maintains the CAF-like property of ATC cells by activating the ECM signaling, which remodels the tumor stromal microenvironment and drives the malignancy of ATC.

Pan Z, Xu T, Bao L, Hu X, Jin T, Chen J

📖 무료 전문 🟢 PMC 전문 PMC9531463

PubMed ↗ DOI ↗ BibTeX ↓ RIS ↓

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