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Incidental Detection of Poorly Differentiated Neuroendocrine Carcinoma in Penile Urethra on 18 F-Fluciclovine PET/CT.

Clinical nuclear medicine 2025 Vol.50(12) p. 1238-1239

Wang SH, Wang LY, Li CY, Shih HJ, Lin CY

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We report the case of an 88-year-old man with suspected biochemical recurrence of prostate cancer, in whom 18 F-fluciclovine PET/CT was performed in the context of rising prostate-specific antigen (PS

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APA Wang SH, Wang LY, et al. (2025). Incidental Detection of Poorly Differentiated Neuroendocrine Carcinoma in Penile Urethra on 18 F-Fluciclovine PET/CT.. Clinical nuclear medicine, 50(12), 1238-1239. https://doi.org/10.1097/RLU.0000000000006028
MLA Wang SH, et al.. "Incidental Detection of Poorly Differentiated Neuroendocrine Carcinoma in Penile Urethra on 18 F-Fluciclovine PET/CT.." Clinical nuclear medicine, vol. 50, no. 12, 2025, pp. 1238-1239.
PMID 40523239

Abstract

We report the case of an 88-year-old man with suspected biochemical recurrence of prostate cancer, in whom 18 F-fluciclovine PET/CT was performed in the context of rising prostate-specific antigen (PSA) levels. Incidental identification of penile urethral activity was observed. A subsequent urethral biopsy revealed a treatment-related, poorly differentiated neuroendocrine carcinoma of prostatic origin, with metastasis to the penile urethra.

MeSH Terms

Humans; Male; Carboxylic Acids; Positron Emission Tomography Computed Tomography; Incidental Findings; Aged, 80 and over; Cyclobutanes; Carcinoma, Neuroendocrine; Cell Differentiation; Urethral Neoplasms

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