A well-known marker for predicting peritoneal metastasis in gastric cancer: carbohydrate antigen 125.
1/5 보강
PICO 자동 추출 (휴리스틱, conf 2/4)
유사 논문P · Population 대상 환자/모집단
361 patients with 61 peritoneal metastases and 25 distant organ metastasis were included in the study.
I · Intervention 중재 / 시술
추출되지 않음
C · Comparison 대조 / 비교
추출되지 않음
O · Outcome 결과 / 결론
[CONCLUSION] CA 125 is an effective, non-invasive, easily accessible marker for predicting peritoneal metastasis. At levels > 22.75 U/mL, the risk of peritoneal metastasis in gastric cancer can be predicted.
[OBJECTIVES] Detection of peritoneal metastasis in gastric cancer is still not successful enough despite all the tests performed.
- p-value p < 0.001
- p-value p = 0.087
- Sensitivity 73.5%
- Specificity 77.7%
APA
Pehlevan-Özel H, Şahingöz E, et al. (2026). A well-known marker for predicting peritoneal metastasis in gastric cancer: carbohydrate antigen 125.. Cirugia y cirujanos, 94(1), 1-6. https://doi.org/10.24875/CIRU.230005371
MLA
Pehlevan-Özel H, et al.. "A well-known marker for predicting peritoneal metastasis in gastric cancer: carbohydrate antigen 125.." Cirugia y cirujanos, vol. 94, no. 1, 2026, pp. 1-6.
PMID
41746730 ↗
Abstract 한글 요약
[OBJECTIVES] Detection of peritoneal metastasis in gastric cancer is still not successful enough despite all the tests performed. In this study, the success of five well-known and commonly used tumor markers in detecting peritoneal metastasis was investigated.
[METHOD] A total of 361 patients with 61 peritoneal metastases and 25 distant organ metastasis were included in the study. The relationship between tumor markers and peritoneal metastases was investigated.
[RESULTS] There was a statistically significant correlation between carbohydrate antigen (CA) 125 and the presence of peritoneal metastasis in gastric cancer (p < 0.001). CA 125 values > 22.75 U/mL were significantly associated with peritoneal metastasis (Area under the curve: 0.771, Sensitivity: 73.5%, Specificity: 77.7%, 95% confidence interval: 0.667-0.875). No correlation was found between the presence of peritoneal metastasis and carcinoembryonic antigen, CA 19-9, CA 15-3, and α-fetoprotein levels (p = 0.197, p = 0.087, p = 0.497, p = 0.128, respectively).
[CONCLUSION] CA 125 is an effective, non-invasive, easily accessible marker for predicting peritoneal metastasis. At levels > 22.75 U/mL, the risk of peritoneal metastasis in gastric cancer can be predicted.
[METHOD] A total of 361 patients with 61 peritoneal metastases and 25 distant organ metastasis were included in the study. The relationship between tumor markers and peritoneal metastases was investigated.
[RESULTS] There was a statistically significant correlation between carbohydrate antigen (CA) 125 and the presence of peritoneal metastasis in gastric cancer (p < 0.001). CA 125 values > 22.75 U/mL were significantly associated with peritoneal metastasis (Area under the curve: 0.771, Sensitivity: 73.5%, Specificity: 77.7%, 95% confidence interval: 0.667-0.875). No correlation was found between the presence of peritoneal metastasis and carcinoembryonic antigen, CA 19-9, CA 15-3, and α-fetoprotein levels (p = 0.197, p = 0.087, p = 0.497, p = 0.128, respectively).
[CONCLUSION] CA 125 is an effective, non-invasive, easily accessible marker for predicting peritoneal metastasis. At levels > 22.75 U/mL, the risk of peritoneal metastasis in gastric cancer can be predicted.
🏷️ 키워드 / MeSH 📖 같은 키워드 OA만
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🏷️ 같은 키워드 · 무료전문 — 이 논문 MeSH/keyword 기반
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