Five daucane-type sesquiterpenes isolated from the roots of Pall. ex Schult. and their anti-gastric cancer activity.
1/5 보강
PICO 자동 추출 (휴리스틱, conf 2/4)
유사 논문P · Population 대상 환자/모집단
The MTT assay was employed to evaluate its antitumor activity.
I · Intervention 중재 / 시술
추출되지 않음
C · Comparison 대조 / 비교
추출되지 않음
O · Outcome 결과 / 결론
The results indicated that compounds , and exhibited potent cytotoxicity against gastric cancer cells with IC values of 14.27 ± 0.4 μM, 18.71 ± 1.2 μM and 21.83 ± 3.4 μM, respectively. Compound displayed moderate inhibition with an IC value of 45.66 ± 1.9 μM.
Two new daucane-type sesquiterpenes () and three known compounds () were isolated from the dried roots of Pall.
APA
Chang X, Wang G, et al. (2026). Five daucane-type sesquiterpenes isolated from the roots of Pall. ex Schult. and their anti-gastric cancer activity.. Natural product research, 1-6. https://doi.org/10.1080/14786419.2026.2625444
MLA
Chang X, et al.. "Five daucane-type sesquiterpenes isolated from the roots of Pall. ex Schult. and their anti-gastric cancer activity.." Natural product research, 2026, pp. 1-6.
PMID
41668466
Abstract
Two new daucane-type sesquiterpenes () and three known compounds () were isolated from the dried roots of Pall. ex Schult., their structures were elucidated through comprehensive 1D and 2D NMR spectroscopy, high-resolution electrospray ionisation mass spectrometry (HR-ESI-MS), experimental and calculated (ECD) spectra, and other complementary methods. The MTT assay was employed to evaluate its antitumor activity. The results indicated that compounds , and exhibited potent cytotoxicity against gastric cancer cells with IC values of 14.27 ± 0.4 μM, 18.71 ± 1.2 μM and 21.83 ± 3.4 μM, respectively. Compound displayed moderate inhibition with an IC value of 45.66 ± 1.9 μM.
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