Shi L ⚠ 동명이인 가능성

[BACKGROUND] Acute myeloid leukemia (AML) is a heterogeneous hematologic malignancy with poor overall survival (OS). Resistance to chemotherapeutic drugs such as idarubicin (IDA) remains a major cause of treatment failure. This study invest…

[OBJECTIVE] To analyze the clinical characteristics, treatment, and prognosis of seven pediatric patients with Acute myeloid leukemia (AML) positive for the t(16;21)(p11;q22) FUS::ERG fusion gene. [METHODS] A retrospective analysis was car…

[BACKGROUND] Early failure less than 12 months (POD12) of frontline R-CHOP chemo-immunotherapy in very poor outcomes and requires alternative therapy in patients with Diffuse large B-cell lymphoma (DLBCL). [AIM] We aim to evaluate the asso…

Natural killer (NK) cells play a key role in the standard treatment of diffuse large B-cell lymphoma (DLBCL). However, NK cells in DLBCL patients frequently display an exhausted phenotype, which is associated with poor clinical outcomes. Th…

Messenger RNA (mRNA)-based therapeutics hold great potential for effectively treating various diseases. However, the targeting of mRNA delivered by systemically administered lipid nanoparticles (LNP) is currently limited to the liver. Safe …

Thyroid carcinoma is among the most common endocrine system malignancies. Lactate metabolism and lactylation modification roles in carcinogenesis and development have garnered more interest in recent years. The expression and function of la…

[PURPOSE] Recent clinical guidelines have broadened the criteria for BRCA counseling and testing for women and men, including indications based on family history, personal history, and current diagnosis of breast, ovarian, pancreatic, and p…

[INTRODUCTION] Colorectal carcinoma (CRC) is a leading cause of gastrointestinal malignancy worldwide. Its development is closely linked to aberrant activation of NF-κB and Akt signaling pathways. This study aimed to evaluate the inhibitory…

To explore the effects of mindfulness training on emotion and sleep quality in patients with colorectal cancer. A total of 44 patients diagnosed with colorectal cancer from a hospital in Chongqing were recruited between August 2021 and Apri…

This study aimed to comprehensively investigate the regulatory mechanism and clinical value of secreted phosphoprotein 1 (SPP1) in the three-stage progression of "smoking-chronic obstructive pulmonary disease (COPD)-carcinogenesis" in lung …

Gastrointestinal (GI) cancers represent a major global health concern due to their high incidence and mortality rates. Foundation models (FMs), also referred to as large models, represent a novel class of artificial intelligence technologie…

[OBJECTIVE] Our aim was to investigate the effect of the clinical application of Traditional Chinese Medicine (TCM) combined with chemotherapy in the treatment of advanced pancreatic cancer. [METHODS] The study participants were divided in…

[PURPOSE] Trimethylamine N-oxide (TMAO), a gut microbiome-derived metabolite, and its precursors (carnitine, choline, betaine) have not been fully examined in relation to thyroid cancer (TC) risk. The aim of this study was to assess the val…

[CONTEXT] At present, medical practitioners commonly use surgery and perioperative chemotherapy, radiotherapy, and biological targeted therapy in clinical treatment of gastric cancer. Western medicine treatment can quickly treat patients' l…

[BACKGROUND] Hyaluronic acid (HA) dermal fillers injection is a common procedure in patients with cosmetic needs. Concomitant pain is a major complaint among patients undergoing HA filler injections. Relevant research is limited and there i…

Dysregulation of long noncoding RNAs (lncRNAs) has been associated with the development and progression of many human cancers. Lactate dehydrogenase A (LDHA) enzymatic activity is also crucial for cancer development, including the developme…

[PURPOSE] Host immunity influences the impact of cancer therapy but the effect of immune status in radioiodine (RAI)-treated differentiated thyroid cancer (DTC) remains obscure. Here we investigated indoleamine 2,3-dioxygenase (IDO) activit…

[PURPOSE] Management of progressive, metastatic radioactive iodine refractory differentiated thyroid cancer (RAIR-DTC) has been a great challenge due to its poor prognosis and limited treatment options. Recently, apatinib, an orally anti-an…

[BACKGROUND] We designed this study to share our management experiences on spinal extradural arachnoid cysts (SEACs) to add more to the body of evidence for their treatment. [METHODS] We retrospectively reviewed 41 patients who underwent m…

[INTRODUCTION] The size and shape of the chin strongly influence facial profile and harmony. The current correction of chin deficiency mostly relies on genioplasty surgery involving osteotomy. To avoid osteotomy, one possible alternative is…

[OBJECTIVE] ?To explore the effectiveness of transplantation of engraved autologous costal cartilage for individualized surgical management in secondary rhinoplasty for cleft lip. [METHODS] ?Between September 2009 and January 2014, 350 pat…

[OBJECTIVE] To study the combination of Mandibular distraction and orthognathic techniques for the reconstruction of adult hemifacial microsomia. [METHODS] The three-dimensional CT reconstruction data was used with Mimics for preoperation …

Expanded polytetrafluoroethylene implant is usually considered as a wonderful implant for chin cosmetic augmentation with no or less bone resorption compared with solid silicone implant. However, one severe bony erosion in expanded polytetr…