Efficient synthesis of new isopavine alkaloids derived from (-)-reframidine and evaluation of their anti-proliferative effect against gastric cancer cells.
1/5 보강
A novel series of isopavine alkaloid reframidine with different substituent groups on the benzyl group of nitrogen was synthesised based on our reported enantioselective total synthesis route.
APA
Pu LY, Li L, et al. (2026). Efficient synthesis of new isopavine alkaloids derived from (-)-reframidine and evaluation of their anti-proliferative effect against gastric cancer cells.. Natural product research, 40(7), 1762-1769. https://doi.org/10.1080/14786419.2024.2431991
MLA
Pu LY, et al.. "Efficient synthesis of new isopavine alkaloids derived from (-)-reframidine and evaluation of their anti-proliferative effect against gastric cancer cells.." Natural product research, vol. 40, no. 7, 2026, pp. 1762-1769.
PMID
39621825 ↗
Abstract 한글 요약
A novel series of isopavine alkaloid reframidine with different substituent groups on the benzyl group of nitrogen was synthesised based on our reported enantioselective total synthesis route. These reframidine derivatives, in particular, were found to provide anti-proliferative and pro-apoptotic activity against gastric cancer cells, which broadened the bioactivities beyond the traditional pharmacological neuroprotective properties of this kind of natural products.
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🏷️ 같은 키워드 · 무료전문 — 이 논문 MeSH/keyword 기반
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