Clinical Translation of Antibody Positron Emission Tomography for Cancer Imaging.
Hepatocellular carcinoma (HCC) lacks precise and noninvasive diagnostic tools.
APA
Seo Y, Flavell RR (2026). Clinical Translation of Antibody Positron Emission Tomography for Cancer Imaging.. Clinical cancer research : an official journal of the American Association for Cancer Research, 32(3), 445-446. https://doi.org/10.1158/1078-0432.CCR-25-3784
MLA
Seo Y, et al.. "Clinical Translation of Antibody Positron Emission Tomography for Cancer Imaging.." Clinical cancer research : an official journal of the American Association for Cancer Research, vol. 32, no. 3, 2026, pp. 445-446.
PMID
41329470
Abstract
Hepatocellular carcinoma (HCC) lacks precise and noninvasive diagnostic tools. To address this, a new positron emission tomography (PET) radiotracer, [68Ga]Ga-XH-06, was developed. It uses an antibody fragment to target glypican-3 (GPC3), a highly specific biomarker, successfully visualizing GPC3 expressions in patients with HCC, potentially meeting an important unmet need. See related article by Lin et al., p. 550.
MeSH Terms
Humans; Positron-Emission Tomography; Carcinoma, Hepatocellular; Liver Neoplasms; Glypicans; Radiopharmaceuticals; Gallium Radioisotopes; Neoplasms; Animals
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