전체 논문 (37편 · 1/2)
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Ex vivo and in vivo CRISPR/Cas9 screenings identify the roles of protein N-glycosylation in regulating T-cell activation and functions.
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Identification of a translocation as a novel oncogene in myeloid leukemia.
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Single-cell atlas of AML reveals age-related gene regulatory networks in t(8;21) AML.
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Blocking SHP2 benefits FGFR2 inhibitor and overcomes its resistance in -amplified gastric cancer.
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Citalopram exhibits immune-dependent anti-tumor effects by modulating C5aR1 TAMs.
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Robust assessment of asymmetric division in colon cancer cells.
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Deep learning linking mechanistic models to single-cell transcriptomics data reveals transcriptional bursting in response to DNA damage.
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p53-induced RNA-binding protein ZMAT3 inhibits transcription of a hexokinase to suppress mitochondrial respiration in human cancer cells.
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Uev1A counteracts oncogenic stimuli in both polyploid and diploid cells.
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Replication stress-inducing ELF3 upregulation promotes BRCA1-deficient breast tumorigenesis in luminal progenitors.
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Repression of PRMT activities sensitize human homologous recombination-proficient ovarian and breast cancer cells to PARP inhibitor treatment.
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long noncoding RNA acts in both - and -acting transcriptional regulation and controls nucleolar biology.
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Propionyl-CoA carboxylase subunit B regulates anti-tumor T cells in a pancreatic cancer mouse model.
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ME3BP-7 is a targeted cytotoxic agent that rapidly kills pancreatic cancer cells expressing high levels of monocarboxylate transporter MCT1.
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Opposing regulation of TNF responses by IFN-γ and a PGE2-cAMP axis that is apparent in rheumatoid and immune checkpoint inhibitor-induced arthritis human IL-1β+ macrophages.
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Human multiethnic radiogenomics reveals low-abundancy microRNA signature in plasma-derived extracellular vesicles for early diagnosis and molecular subtyping of pancreatic cancer.
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Artificial intelligence approaches for tumor phenotype stratification from single-cell transcriptomic data.
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Rearrangement of 3D genome organization in breast cancer epithelial to mesenchymal transition and metastasis organotropism.
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Causal associations between human plasma proteins and prostate cancer identified by proteome-wide Mendelian randomization.
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Single-cell dissection of prognostic architecture and immunotherap response in infection-associated gastric cancer.
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NOLC1 suppresses immunochemotherapy by inhibiting p53-mediated ferroptosis in gastric cancer.
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Endoscopic liquid biopsies of gastric fluid in a large human patient cohort reveal DNA content as a candidate tumor biomarker in gastric cancer.
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Telomeres control human telomerase () expression through non-telomeric TRF2.
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TopBP1 biomolecular condensates as a new therapeutic target in advanced-stage colorectal cancer.
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Sex differences in bile acid homeostasis and excretion underlie the disparity in liver cancer incidence between males and females.
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Spatially defined multicellular functional units in colorectal cancer revealed from single cell and spatial transcriptomics.
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RBMX2 links infection to epithelial-mesenchymal transition and lung cancer progression.
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Therapeutic benefits of maintaining CDK4/6 inhibitors and incorporating CDK2 inhibitors beyond progression in breast cancer.
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Optimal transport for automatic alignment of untargeted metabolomic data.
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Actin networks modulate heterogeneous NF-κB dynamics in response to TNFα.