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15건 · 최신순-
Deep Inferior Artery Perforator Flap-Enhanced Recovery After Surgery: Perspectives From Australia's Only Public Cancer-Specific Hospital.
[BACKGROUND] Enhanced recovery after surgery (ERAS) pathways are increasingly utilised in autologous breast reconstruction (ABR) to improve patient outcomes. This Australian study evaluates the impact of our centre's newly standardised elec…
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Efficacy of Microvascular Couplers for Venous Micro-anastomosis in the Reconstruction of Oral Defects.
[BACKGROUND] Head and neck tumors often result in extensive maxillofacial defects requiring complex reconstructive procedures. Free tissue transfer has become the gold standard for reconstruction due to its ability to provide optimal tissue…
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Botulinum Toxin: A Comprehensive Review of Its Molecular Architecture and Mechanistic Action.
Botulinum toxin (BoNT), the most potent substance known to humans, likely evolved not to kill but to serve other biological purposes. While its use in cosmetic applications is well known, its medical utility has become increasingly signific…
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Intraglandular botulinum toxin in postoperative head and neck fistula: a retrospective analysis.
[PURPOSE] Orocervical (OCF) or pharyngocutaneous fistula (PCF) are one of the disastrous complications of head and neck cancer surgery. Conventional standards of management are predominantly conservative. Though a majority of such patients …
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Central Giant Cell Tumour of the Maxillofacial Region: A 10-Year Retrospective Analysis.
[BACKGROUND AND AIM] Central giant cell tumour (CGCT) accounts for …
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The Effects of Botulinum Toxin and Casting in Spastic Children With Cerebral Palsy: A Systematic Review and Meta-Analysis.
Cerebral palsy (CP) is a neurological disorder that affects muscle tone, movement, and motor skills in children. One of the most common symptoms of cerebral palsy is spasticity, which is characterised by involuntary muscle contractions and …
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The Use of Auricular Cartilage Grafts in Septorhinoplasty: A Dual-Centre Study of Donor Site Patient-Reported Outcome Measures.
Objectives The use of autologous grafts is a key aspect of contemporary septorhinoplasty. When septal cartilage is deficient, auricular cartilage serves as a biocompatible, readily accessible alternative. Our study aimed to assess donor sit…
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Evolutionary Features in the Structure and Function of Bacterial Toxins.
Toxins can function both as a harmful and therapeutic molecule, depending on their concentrations. The diversity in their function allows us to ask some very pertinent questions related to their origin and roles: (a) What makes them such ef…
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Pharmacological management of abnormal tone and movement in cerebral palsy.
[BACKGROUND] The evidence base to guide the pharmacological management of tone and abnormal movements in cerebral palsy (CP) is limited, as is an understanding of routine clinical practice in the UK. We aimed to establish details of motor p…
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Donut Mastopexy Lumpectomy.
Advancements in oncoplastic techniques have enhanced commitment to restore shape and, hence, has improved cosmetic outcomes. Donut mastopexy lumpectomy is one such technique and is best utilized in a setting of a malignancy not extending to…
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Therapeutic use of botulinum toxin in pain treatment.
Botulinum toxin is one of the most potent molecule known to mankind. A neurotoxin, with high affinity for cholinergic synapse, is effectively capable of inhibiting the release of acetylcholine. On the other hand, botulinum toxin is therapeu…
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High Yield Preparation of Functionally Active Catalytic-Translocation Domain Module of Botulinum Neurotoxin Type A That Exhibits Uniquely Different Enzyme Kinetics.
Botulinum neurotoxins (BoNTs) are the most toxic proteins known to cause flaccid muscle paralysis as a result of inhibition of neurotransmitter release from peripheral cholinergic synapses. BoNT type A (BoNT/A) is a 150 kDa protein consisti…
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The Botulinum Toxin as a Therapeutic Agent: Molecular Structure and Mechanism of Action in Motor and Sensory Systems.
Botulinum neurotoxin (BoNT) produced by Clostridium botulinum is the most potent molecule known to mankind. Higher potency of BoNT is attributed to several factors, including structural and functional uniqueness, target specificity, and lon…
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The rotational genioplasty: a modified technique for patients with obstructive sleep apnoea.
Obstructive sleep apnoea (OSA) is a serious condition that can be the cause of a number of systemic symptoms and conditions. The diagnosis of OSA is made by clinical and radiological examination, with polysomnography as the gold standard fo…
- Re: Sagittal split genioplasty: a new technique.