전체 논문 (34편 · 1/2)
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Tumor DNA methylation subtypes predict immunotherapy outcomes in pleural mesothelioma patients in the NIBIT-EPI-MESO study.
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Designing synthetic regulatory elements using the generative AI framework DNA-Diffusion.
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Genomic evolution of pancreatic cancer at single-cell resolution.
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Single-nucleus DNA sequencing delves into the varied genomic evolution of pancreatic cancer.
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Polygenic risk scores in thyroid cancer screening, diagnosis and management.
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Author Correction: Zbtb7a suppresses prostate cancer through repression of a Sox9-dependent pathway for cellular senescence bypass and tumor invasion.
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Mutational scanning reveals oncogenic CTNNB1 mutations have diverse effects on signaling.
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Nucleophosmin supports WNT-driven hyperproliferation and tumor initiation.
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Multi-trait and multi-ancestry genetic analysis of comorbid lung diseases and traits improves genetic discovery and polygenic risk prediction.
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Publisher Correction: APOBEC3 mutagenesis drives therapy resistance in breast cancer.
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Aneuploidy-driven vulnerabilities in breast cancer metastasis.
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p53 inactivation drives breast cancer metastasis to the brain through SCD1 upregulation and increased fatty acid metabolism.
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Global multi-ancestry genome-wide analyses identify genes and biological pathways associated with thyroid cancer and benign thyroid diseases.
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Improved polygenic risk prediction models for breast cancer subtypes in women of African ancestry.
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Genome-wide association analyses of autoimmune hypothyroidism reveal autoimmune and thyroid-specific contributions and an inverse relationship with cancer risk.
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Harnessing genomics for early cancer detection, risk stratification and prevention.
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Interpretable, flexible and spatially aware integration of multiple spatial transcriptomics datasets from diverse sources.
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Transcription factor switching drives subtype-specific pancreatic cancer.
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Defining the transcriptional landscape in the classical subtype of pancreatic cancer.
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Phylogenetic inference reveals clonal heterogeneity in circulating tumor cell clusters.
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NKX2-1 drives neuroendocrine transdifferentiation of prostate cancer via epigenetic and 3D chromatin remodeling.
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ERG-driven prostate cancer initiation is cell-context dependent and requires KMT2A and DOT1L.
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Targeting histone H2B acetylated enhanceosomes via p300/CBP degradation in prostate cancer.
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Cracking the histone code for prostate cancer therapy.
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Author Correction: An aberrant SREBP-dependent lipogenic program promotes metastatic prostate cancer.
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Genome-scale CRISPR screens identify PTGES3 as a direct modulator of androgen receptor function in advanced prostate cancer.
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Epigenetically driven and early immune evasion in colorectal cancer evolution.
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TGF-β builds a dual immune barrier in colorectal cancer by impairing T cell recruitment and instructing immunosuppressive SPP1 macrophages.
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Two-pronged immunosuppression by TGFβ supports colorectal cancer metastasis.
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Exploring the origins of pancreatic cancer.