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Global multi-ancestry genome-wide analyses identify genes and biological pathways associated with thyroid cancer and benign thyroid diseases.
Thyroid diseases are common and highly heritable. We performed a meta-analysis of genome-wide association studies from 19 biobanks for five thyroid diseases: thyroid cancer (ThC), benign nodular goiter, Graves' disease, lymphocytic thyroidi…
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Global multi-ancestry genetic study elucidates genes and biological pathways associated with thyroid cancer and benign thyroid diseases.
Thyroid diseases are common and highly heritable. Under the Global Biobank Meta-analysis Initiative, we performed a meta-analysis of genome-wide association studies from 19 biobanks for five thyroid diseases: thyroid cancer, benign nodular …
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Population Prevalence of the Major Thyroid Cancer-Associated Syndromes.
[CONTEXT] Understanding the population prevalence of thyroid cancer-associated syndromes is important to guide germline genetic testing and clinical management. [OBJECTIVE] To estimate the prevalence of the major thyroid cancer-associated …
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Prevalence of the major thyroid cancer-associated syndromes in the United States.
[IMPORTANCE] A subset of thyroid cancers develops in a setting of a known hereditary cancer-associated syndrome. Understanding the population prevalence of thyroid cancer-associated syndromes is important to guide germline genetic testing a…