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Therapeutic Efficacy and Safety of Recombinant Botulinum Toxin Type A for Moderate to Severe Glabellar Lines: A Randomized, Controlled, Double-blind, Phase III Trial in Chinese Adults.
[BACKGROUND] Conventional botulinum toxin type A (BoNT/A) products include non-therapeutic accessory proteins vary in composition and manufacturing processes, which may contribute to differences in purity and biochemical characteristics. YY…
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Safety and Efficacy of Recombinant Botulinum Toxin Type A for Moderate-to-severe Glabellar Lines: A Multicenter Randomized Controlled Trial.
[BACKGROUND] YY001 (Retoxin ®), the first global recombinant botulinum toxin type A (rBoNT/A) tested in humans, contains a pure 150-kDa core neurotoxin identical to natural BoNT/A (nBoNT/A). This study aimed to evaluate the safety and preli…
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Adverse neurological events following botulinum toxin type A: A case series of post-injection seizures and paralysis.
Within the field of rehabilitation and aesthetic medicine, botulinum neurotoxin (BoNT), particularly type A (BoNT-A), has gained significant popularity for its unique muscle-relaxing properties including muscular spasticity and reducing wri…
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TUSILS-SRA: A Modified Way of Costal Cartilage Harvest for Rhinoplasty.
[BACKGROUND] Autogenous rib cartilage is a common material for rhinoplasty, especially for nose extension and revision. At present, open surgery is the most mature method for rib extraction. However, it has many disadvantages, such as long …
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The efficacy and clinical significance of microsurgery on cognitive function, activities of daily living, and serum biomarkers in patients with glioma.
[OBJECTIVE] To evaluate the efficacy of microsurgery on cognitive function, activities of daily living (ADL), and serum biomarkers in patients with glioma. [METHODOLOGY] This was a retrospective study. A total of 120 eligible patients with…
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Diagnosis and Therapeutic Strategies of Unusual Subglottic Pleomorphic Adenoma: A Rare Case Report and Literature Review.
Pleomorphic adenoma (PA) is primarily found in the salivary glands, and is extremely rare in the subglottic region. Here we present a subglottic PA that presented with symptoms of dry cough and dyspnea. A submucosal mass was found in the su…
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Nonhuman Primate Model of Super-selective Intra-arterial Ophthalmic Arterial Interventional Thrombolysis for Treatment of Ophthalmic Arterial Embolism Resulting From Hyaluronic Acid Filler Cosmetic Injection.
[BACKGROUND] Although intravascular interventional thrombolysis therapy is beneficial for patients suffering from impaired vision caused by hyaluronic acid (HA) embolism, there is no medical evidence-base for the efficacy of this treatment.…
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Three-dimensional facial soft-tissue changes after L-shaped reduction malarplasty: A pilot retrospective study.
[PURPOSE] Reduction malarplasty (RM) is a common facial contouring aesthetic procedure in East Asia. However, there is a lack of data on the postoperative changes in soft tissue and patient-reported outcomes. This retrospective study aimed …
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A Combination of Conventional Transconjunctival Lower Blepharoplasty and Percutaneous Nanofat Grafting in a Young Chinese Population With Eyelid Bags and Tear Trough Deformities.
[OBJECTIVE] A simple and minimally invasive combined procedure, including transconjunctival orbital fat removal and transcutaneous resected orbital fat injection, was performed based on the anatomical characteristics of the lower eyelids in…
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Reflections on Aging Series: Multiple Factors Influencing Lower Blepharoplasty Procedure Selection in an East Asian Population.
[BACKGROUND] The lower eyelid, because of its unique functional and anatomical characteristics, is highly susceptible to early signs of aging. There is overlap in the manifestation of age-specific senescent features across age groups, with …
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Complications and patient-reported outcomes after radiotherapy in breast cancer patients undergoing implant-based breast reconstruction: a retrospective study from a large Chinese breast disease center.
[BACKGROUND] Postmastectomy radiation therapy (PMRT) can influence the outcome of implant-based breast reconstruction (IBBR). This study aims to investigate the complications and patient-reported outcomes (PROs) following PMRT between direc…
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The hybrid operation based on microsurgery assisted by intraoperative spinal angiography in patients with spinal dural arteriovenous fistula: a series of 45 cases from multicenter research.
[BACKGROUND] To assess the clinical effects of hybrid surgery, which includes spinal angiography-assisted microsurgery, in the treatment of spinal dural arteriovenous fistulas (SDAVF). [METHODS] We retrospectively reviewed 45 patients who …
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Endoscopic retrosigmoid trans-petrosal fissure approach for vestibular schwannomas: case series.
The management of vestibular schwannoma (VS) remains one of the most formidable challenges in neurosurgery owing to the eloquent nature of surrounding anatomy. Although endoscopy-assisted microsurgery has recently gained momentum in cerebel…
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Botulinum Toxin to Improve the Prognosis of Skin Transplantation: A Short Narrative Review.
Skin transplantation is a traditional and well-established method of repairing skin loss, especially deep second-degree postburn wounds. Complications often happen amid the healing process, including necrosis and skin contracture, which has…
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Aesthetic Improvement of Body Proportion Through Trunk Liposculpture: A Waistline-based Strategy.
[BACKGROUND] Abdominal contouring through liposuction has been practiced for decades. However, few studies have focused on describing the definition and enhancement of the waistline in torso contouring procedures. [OBJECTIVES] In the prese…
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A Systematic Preoperative Evaluation and Skin Excision Design for Incisional Blepharoplasty.
[BACKGROUND] The prevalence of skin redundancy and lack of creases in the Asian upper eyelids makes blepharoplasty popular. Although many incision designs have been developed to improve upper eyelid laxity, there is a lack of a universal me…
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Transcriptomic and Proteomic Characterization of the Immune Response to Elective Spinal Reconstructive Surgery: Impact of Aging and Comparison with Traumatic Injury Response.
[BACKGROUND] Major surgery triggers trauma-like stress responses linked to age, surgery duration, and blood loss, resembling polytrauma. This similarity suggests elective surgery as a surrogate model for studying polytrauma immune responses…
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Regulated extravascular microenvironment reversible thermosensitive hydrogel for inhibiting calcium influx and vasospasm.
Arterial vasospasm after microsurgery can cause severe obstruction of blood flow manifested as low tissue temperature, leading to tissue necrosis. The timely discovery and synchronized treatment become pivotal. In this study, a reversible, …
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Hybrid endoscopic-microscopic surgery for dumbbell-shaped trigeminal schwannoma: case report and literature review.
[BACKGROUND] The surgery of dumbbell-shaped trigeminal neurinomas (TN) remains one of the most formidable challenges for neurosurgeons because of its location at great depth in the cranium and proximity to vital neurovascular structures. […
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Combination of High Ligation and Intraoperative Embolization Using Polidocanol for Treatment of Varicoceles.
Varicoceles are dilated veins within the pampiniform plexus and are relatively common in the general male population. The spermatic vein has many branches in the scrotal segment and then gradually merges into 1-2 trunks after passing throug…
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Fat Compartment Gliding Theory - A Novel Technique for the Repositioning of Superficial Fat Compartments for Facial Rejuvenation.
[BACKGROUND] Facial fat compartments and their role in facial aging have gained increased recognition and are playing a significant role in facial rejuvenation. The superficial fat compartments glide inferiorly during the aging process, lea…
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Rare case of pulmonary fat embolism and acute respiratory distress syndrome after liposuction and fat grafting: a case report.
[BACKGROUND] Pulmonary fat embolism usually occurs after fracture, yet rarely observed after liposuction and fat grafting. [CASE PRESENTATION] We describe a 19-year-old female patient who presented with acute respiratory failure and diffus…
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Vertical V-Y Advancement Lifting Based on Fat Compartments: A New Approach for Lower Eyelid and Midcheek Rejuvenation.
[BACKGROUND] Lower blepharoplasty techniques continue to improve over time. With discovery of the numerous fat compartments of the face, surgeons noticed that the appearance of the lower eyelid area through aging could be improved through m…
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One-Stage Repair of Alveolar Cleft and Nasal Deformities Using Grafts From Nasal Septum: Application of Vomer, Ethmoid, and Septal Cartilage.
[BACKGROUND] Patients with alveolar cleft unrepaired suffer from nasal deformities of different magnitude. Bone and cartilage grafts are harvested through several incisions. In this study, we present a method to simultaneously correct nasal…
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Development of a valid and reliable pterygium surgery assessment scale for ophthalmology residents.
[BACKGROUND] Microsurgery training has become an important part of ophthalmology teaching and one of the main topics of examination. Accurate and effective evaluation of microsurgery skills is vital for the training and teaching of resident…
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Effectiveness of Botulinum Toxin A in Treatment of Hemiplegic Shoulder Pain: A Systematic Review and Meta-analysis.
[OBJECTIVE] To evaluate the effectiveness of botulinum toxin A (BTX-A) in the treatment of hemiplegic shoulder pain. [DATA SOURCES] PubMed, EMBASE, Elsevier, Springer, Cochrane Library, Physiotherapy Evidence Database, CNKI, and VIP were r…
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Application of a Proposed Multi-Positional Circumferential Arm Liposuction Method and Quantification of its Clinical Efficacy Evaluation.
[BACKGROUND] Upper arm liposuction mainly focuses on the posterolateral region, which may lead to a lack of harmony between the aspirated and unaspirated areas. In addition, the treatment effect of arm liposuction is often evaluated only by…
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Fan-Shaped Thin Fat Pedicles for Tear Trough Correction Through a Layer-Level Fixation: A Modified Transconjunctival Blepharoplasty.
Fat repositioning is an effective way to treat tear trough deformity (TTD) in Asians. Recent techniques mainly focused on the fixation technique, whereas how to precisely shape and individually quantify the fat pedicle has been ignored. Thi…
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A Modified Cosmetic Genioplasty Can Affect Airway Space Positively in Skeletal Class II Patients: Studying Alterations of Hyoid Bone Position and Posterior Airway Space.
[BACKGROUND] Improving the posterior airway space is one of the most important functions of genioplasty. Studies have shown that the posterior airway space (PAS) can play an important role in the evaluation of obstructive sleep apnea syndro…
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A Novel Way for Upper Eyelid Rejuvenation by Combination of Local Fat-Fascia-Muscle Flap Repositioning for Middle-Aged Asian Women.
[BACKGROUND] Upper eyelid aging is common among middle-aged Asians. Apart from skin aging, there has been an increasing recognition for the role of sunken eyelid playing in upper eyelid aging. Various methods have been developed to deal wit…