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Transcriptome patterns in hidradenitis suppurativa: support for the role of antimicrobial peptides and interferon pathways in disease pathogenesis.
[BACKGROUND] Hidradenitis suppurativa (HS) is a recurrent inflammatory disease of the apocrine sweat glands. Immune dysregulation probably contributes to the pathogenesis of HS. [AIM] To harness mRNA expression arrays to investigate the tr…
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Utility of a human-mouse xenograft model and in vivo near-infrared fluorescent imaging for studying wound healing.
To study the complex cellular interactions involved in wound healing, it is essential to have an animal model that adequately mimics the human wound microenvironment. Currently available murine models are limited because wound contraction i…