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3건 · 최신순-
Genetic alterations in 'normal' luminal and myoepithelial cells of the breast.
Chromosomal loci exhibiting loss of heterozygosity (LOH) at high frequency in invasive breast cancer have been investigated in 'normal' breast tissue from patients with carcinoma and from reduction mammoplasty specimens. Duct-lobular units …
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Human breast epithelial xenografts: an immunocytochemical and ultrastructural study of differentiation and lactogenic response.
Fragments of ductal and lobular epithelium ('organoids') produced by collagenase digestion of reduction-mammoplasty specimens were injected into athymic 'nude' mice. These heterospecific tissues were accepted without rejection, and the pres…
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Clonal analysis of expression of epithelial antigens in cultures of normal human breast.
Cells from normal human breast epithelium were cloned in monolayer culture and the clones were stained with monoclonal antibodies. Tissue was from reduction mammoplasty operations. Cloning efficiencies were 5-30%. Two types of clone were id…